The short version
Only one company currently supplies this market — there is no backup if it stumbles.
The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.
Nighttime Cold and Flu
Acetaminophen, Dextromethrophan HBr, Doxylamine succinate · DOXYLAMINE SUCCINATE 12.5 mg/30mL; ACETAMINOPHEN 650 mg/30mL; DEXTROMETHORPHAN HYDROBROMIDE 30 mg/30mL · Liquid · Oral · Kroger
NDC 41226-0782-01 · 354 mL in 1 BOTTLE · OTC MONOGRAPH DRUG · View full market →
Medicare Part D
Medicare Part D does not cover over-the-counter drugs — by law it pays only for products requiring a prescription.
How Part D pricing works →NADAC price per unit
No NADAC pricing on file for this NDC — NADAC covers drugs dispensed by retail community pharmacies.
Supply fragility
Not scored — fragility is computed for NADAC-priced NDCs.
Is this a "specialty" drug?
There's no legal definition — it meets 1 of 6 public criteria. Why that matters →
- Part D specialty tier
- Costs ≥ $950/fill
- Biologic (BLA)
- Injectable / infused
- Orphan-drug exclusivity
- REMS program · Opioid Analgesic REMS Shared System REMS
Regulatory
- Application
- M012
- TE code
- —
- Approval date
- —
- Patents / exclusivity
- None on file
Shortage history
No FDA shortage reports for this drug or its presentations.
Recalls (this NDC)
No enforcement reports list this package NDC.
Manufacturers of Acetaminophen, Dextromethrophan HBr, Doxylamine succinate (Liquid)
| Labeler | Strength | First seen | Last seen |
|---|---|---|---|
| Kroger | DEXTROMETHORPHAN HYDROBROMIDE 30 mg/30mL; DOXYLAMINE SUCCINATE 12.5 mg/30mL; ACETAMINOPHEN 650 mg/30mL | Aug 26, 2026 | Sep 2, 2026 |
| Kroger | DOXYLAMINE SUCCINATE 12.5 mg/30mL; ACETAMINOPHEN 650 mg/30mL; DEXTROMETHORPHAN HYDROBROMIDE 30 mg/30mL | Aug 26, 2026 | Sep 2, 2026 |
| Kroger | DEXTROMETHORPHAN HYDROBROMIDE 650 mg/30mL; DOXYLAMINE SUCCINATE 30 mg/30mL; ACETAMINOPHEN 12.5 mg/30mL | Jul 22, 2026 | Aug 19, 2026 |
| Kroger | DOXYLAMINE SUCCINATE 650 mg/30mL; ACETAMINOPHEN 30 mg/30mL; DEXTROMETHORPHAN HYDROBROMIDE 12.5 mg/30mL | Jul 22, 2026 | Aug 19, 2026 |
| Kroger | ACETAMINOPHEN 650 mg/30mL; DEXTROMETHORPHAN HYDROBROMIDE 30 mg/30mL; DOXYLAMINE SUCCINATE 12.5 mg/30mL | Jul 15, 2026 | Jul 16, 2026 |
Roster from daily NDC Directory diffs — first/last seen dates start July 2026.
Cite this page
DrugDashboards, "Nighttime Cold and Flu — NDC 41226-0782-01," retrieved September 3, 2026, https://drugdashboards.com/drug/41226078201.
Free to cite with attribution — see how the data is put together.