DrugDashboards

Delestrogen

estradiol valerate · ESTRADIOL VALERATE 20 mg/mL · Injection · Intramuscular · Par Health USA, LLC

NDC 42023-0111-01 · 5 mL in 1 VIAL, MULTI-DOSE · NDA · View full market →

The short version

Just 3 companies supply this market — thin enough that a single exit would be felt immediately. The brand price has held steady around $35.74 per mL over the past year. Put together: this looks like a healthy supply — the boring kind, which is exactly what you want. Historically, drugs in this position went on to a new shortage within 90 days about 0.4% of the time — roughly 3× the typical drug (0.1%).

The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.

One drug, every price

The same NDC has different prices depending on who is paying. Units differ between rungs — compare within a rung over time, not rung against rung, unless the units match.

ⓘ How this was built
Data sources
  • CMS NADAC (pharmacy acquisition, weekly)
  • CMS Part B ASP quarterly payment limits
  • CMS Maximum Fair Prices (IRA negotiated, NDC-level)
  • Medicare Part D Spending by Drug (data.cms.gov, name-matched)
  • VA FSS / Big4 federal contract prices (va.gov, twice monthly)
  • ACA Federal Upper Limits + weighted AMP (data.medicaid.gov, monthly)
  • California SB-17 WAC filings (list price, per package)
Method

Each rung is the newest figure for this NDC from one federal price system, shown with its own unit. Part D is matched by drug name because CMS publishes no NDCs there; it is gross spending, before confidential rebates.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

  • Pharmacies pay (NADAC)$35.74per MLinvoice-surveyed acquisition cost · Aug 19, 2026
  • Medicare Part B pays (ASP+6%)$7.70per billing unit (10 MG)HCPCS J1380 · Jul 1, 2026
  • Part D plans paid (avg)$30.53per dosage unitgross, before rebates — matched by drug name · 2024
  • Part D point of sale (median)$35.50per unitnegotiated price across 2 plans — before rebates · Jul 1, 2024
  • Federal ceiling (Big4)$95.89per package of 5MLEndo USA, Inc. · Jan 1, 2026

Medicare Part D

All Part D pricing →
ⓘ How this was built
Data sources
  • CMS quarterly Prescription Drug Plan Formulary & Pricing files (SPUF)
Method

Negotiated 30-day point-of-sale unit prices and formulary terms aggregated across every unsuppressed Part D and MA-PD plan for the quarter shown. Point of sale means gross of confidential rebates. CMS publishes one representative NDC per drug concept (RxCUI) rather than every package, so these figures come from CMS's representative package for the same drug — matched on generic name, strength, and dosage form. Estimated from MedPAC's program-wide rebate aggregates (June 2023: DIR = 29% of gross Part D spending; brand rebates ≈ 25–40% of gross, generics minimal). Actual rebates are confidential and vary widely by drug — this is a range, not a fact about this drug.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

Plans pay at point of sale
$35.50per unit
middle half $35.50$35.50 · 2 plans · Jul 1, 2024
Est. net of rebates
$21.30–$26.63
brand drug — est. 25-40% rebate off the price at left
Coverage & restrictions
of plans cover it

*No drug-level rebate is public — the estimate applies MedPAC's program-wide brand rebate range to this drug's gross price. Tracked here for 3 quarters since 2024.

NADAC price per unit

$0$20.00$40.00Sep 2014Sep 2026$35.74
37 price points · per MLSource: CMS NADAC

Estimated fill cost

WAC per package, as filed
$187.07
Reported to Texas DSHS · 2026 annual filing · Par Health USA, LLC

Manufacturer list price as filed — not what pharmacies actually pay after discounts.

Medicare Part B (ASP)

Payment limit per 10 MG
$7.702
HCPCS J1380 · Jul 1, 2026 quarter · typically ASP + 6%

Medicaid spend (2025)

$471,098
3,058 prescriptions paid by Medicaid nationally · all Medicaid spend →

Supply fragility

20Low risk

Some pressure is visible, but not much — here’s everything the score found to count.

  • 3 active manufacturers+10
  • sterile injectable+10

The score counts pressure that is already visible — fewer makers, shortages, recalls, falling prices. 0 means none of it; 100 means all of it at once. Recomputed daily · as of Sep 3, 2026

90-day shortage risk (model v2)

0.4%chance of a new FDA shortage posting for estradiol valerate (injectable) in the next 90 days

sterile injectable · sole-source market

For scale: the typical drug’s chance is about 0.1% — this one is 3× that.

Backtested statistical model over the whole market, not this package alone. Model details →

Is this a "specialty" drug?

There's no legal definition — it meets 1 of 6 public criteria. Why that matters →

  • Part D specialty tier
  • Costs ≥ $950/fill · avg $162.90 per prescription
  • Biologic (BLA)
  • Injectable / infused
  • Orphan-drug exclusivity
  • REMS program

Regulatory

Application
NDA009402
TE code
AO
Approval date
Jan 1, 1982
Patents / exclusivity
None on file

Shortage history

No FDA shortage reports for this drug or its presentations.

Recalls (this NDC)

No enforcement reports list this package NDC.

Manufacturers of estradiol valerate (Injection)

LabelerStrengthFirst seenLast seen
Hikma Pharmaceuticals USA Inc.ESTRADIOL VALERATE 20 mg/mLJul 15, 2026Sep 2, 2026
Hikma Pharmaceuticals USA Inc.ESTRADIOL VALERATE 10 mg/mLJul 15, 2026Sep 2, 2026
Hikma Pharmaceuticals USA Inc.ESTRADIOL VALERATE 40 mg/mLJul 15, 2026Sep 2, 2026
Par Health USA, LLCESTRADIOL VALERATE 20 mg/mLJul 15, 2026Sep 2, 2026
Par Health USA, LLCESTRADIOL VALERATE 10 mg/mLJul 15, 2026Sep 2, 2026
Xiromed, LLCESTRADIOL VALERATE 20 mg/mLJul 15, 2026Sep 2, 2026
Xiromed, LLCESTRADIOL VALERATE 10 mg/mLJul 15, 2026Sep 2, 2026
Xiromed, LLCESTRADIOL VALERATE 40 mg/mLJul 15, 2026Sep 2, 2026

Roster from daily NDC Directory diffs — first/last seen dates start July 2026.

Cite this page

DrugDashboards, "Delestrogen — NDC 42023-0111-01," retrieved September 3, 2026, https://drugdashboards.com/drug/42023011101.

Free to cite with attribution — see how the data is put together.