The short version
24 companies supply this market — deep enough that no single failure threatens the supply.
The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.
Metformin hydrochloride · METFORMIN HYDROCHLORIDE 750 mg/1 · Tablet, Extended Release · Oral · AvKARE
NDC 42291-0824-10 · 1000 TABLET, EXTENDED RELEASE in 1 BOTTLE · ANDA · View full market →
24 companies supply this market — deep enough that no single failure threatens the supply.
The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.
Matched to CMS's representative package for this drug (NDC 67877-0414-01) — same generic, strength, and dosage form. CMS prices one NDC per drug concept, not every package.
Negotiated 30-day point-of-sale unit prices and formulary terms aggregated across every unsuppressed Part D and MA-PD plan for the quarter shown. Point of sale means gross of confidential rebates. CMS publishes one representative NDC per drug concept (RxCUI) rather than every package, so these figures come from CMS's representative package for the same drug — matched on generic name, strength, and dosage form. Estimated from MedPAC's program-wide rebate aggregates (June 2023: DIR = 29% of gross Part D spending; brand rebates ≈ 25–40% of gross, generics minimal). Actual rebates are confidential and vary widely by drug — this is a range, not a fact about this drug.
Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.
*No drug-level rebate is public — the estimate applies MedPAC's program-wide brand rebate range to this drug's gross price. Tracked here for 10 quarters since 2024.
No NADAC pricing on file for this NDC — NADAC covers drugs dispensed by retail community pharmacies.
Not scored — fragility is computed for NADAC-priced NDCs.
OAI inspection at a producing facility (24 months) · sole-source market
For scale: the typical drug’s chance is about 0.1% — this one is in ordinary territory.
Backtested statistical model over the whole market, not this package alone. Model details →
No FDA shortage reports for this drug or its presentations.
No enforcement reports list this package NDC.
| Labeler | Strength | First seen | Last seen |
|---|---|---|---|
| A-S Medication Solutions | METFORMIN HYDROCHLORIDE 500 mg/1 | Jul 15, 2026 | Sep 3, 2026 |
| Ajanta Pharma USA Inc. | METFORMIN HYDROCHLORIDE 1000 mg/1 | Jul 15, 2026 | Sep 3, 2026 |
| Aphena Pharma Solutions - Tennessee, LLC | METFORMIN HYDROCHLORIDE 750 mg/1 | Jul 15, 2026 | Sep 3, 2026 |
| Aphena Pharma Solutions - Tennessee, LLC | METFORMIN HYDROCHLORIDE 500 mg/1 | Jul 15, 2026 | Sep 3, 2026 |
| Ascend Laboratories, LLC | METFORMIN HYDROCHLORIDE 500 mg/1 | Jul 15, 2026 | Sep 3, 2026 |
| Aurobindo Pharma Limited | METFORMIN HYDROCHLORIDE 750 mg/1 | Jul 15, 2026 | Sep 3, 2026 |
| Aurobindo Pharma Limited | METFORMIN HYDROCHLORIDE 500 mg/1 | Jul 15, 2026 | Sep 3, 2026 |
| Bryant Ranch Prepack | METFORMIN HYDROCHLORIDE 500 mg/1 | Jul 15, 2026 | Sep 3, 2026 |
| Bryant Ranch Prepack | METFORMIN HYDROCHLORIDE 750 mg/1 | Jul 15, 2026 | Sep 3, 2026 |
| Lupin Pharmaceuticals, Inc. | METFORMIN HYDROCHLORIDE 1000 mg/1 | Jul 15, 2026 | Sep 3, 2026 |
| Marlex Pharmaceuticals, Inc. | METFORMIN HYDROCHLORIDE 750 mg/1 | Sep 3, 2026 | Sep 3, 2026 |
| Marlex Pharmaceuticals, Inc. | METFORMIN HYDROCHLORIDE 500 mg/1 | Sep 3, 2026 | Sep 3, 2026 |
| Northwind Health Company, LLC | METFORMIN HYDROCHLORIDE 500 mg/1 | Jul 15, 2026 | Sep 3, 2026 |
| NuCare Pharmaceuticals, Inc. | METFORMIN HYDROCHLORIDE 500 mg/1 | Jul 15, 2026 | Sep 3, 2026 |
| Preferred Pharmaceuticals Inc. | METFORMIN HYDROCHLORIDE 500 mg/1 | Jul 15, 2026 | Sep 3, 2026 |
| Proficient Rx LP | METFORMIN HYDROCHLORIDE 500 mg/1 | Jul 15, 2026 | Sep 3, 2026 |
| Proficient Rx LP | METFORMIN HYDROCHLORIDE 750 mg/1 | Jul 15, 2026 | Sep 3, 2026 |
| Remedyrepack Inc. | METFORMIN HYDROCHLORIDE 750 mg/1 | Jul 15, 2026 | Sep 3, 2026 |
| Ascend Laboratories, LLC | METFORMIN HYDROCHLORIDE 750 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Aurobindo Pharma Limited | METFORMIN HYDROCHLORIDE 1000 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| AvKARE | METFORMIN HYDROCHLORIDE 500 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| AvKARE | METFORMIN HYDROCHLORIDE 750 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| AvPAK | METFORMIN HYDROCHLORIDE 500 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| AvPAK | METFORMIN HYDROCHLORIDE 750 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Bryant Ranch Prepack | METFORMIN HYDROCHLORIDE 1000 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Calvin Scott & Co., Inc. | METFORMIN HYDROCHLORIDE 500 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Coupler LLC | METFORMIN HYDROCHLORIDE 750 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Epic Pharma, LLC | METFORMIN HYDROCHLORIDE 750 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Epic Pharma, LLC | METFORMIN HYDROCHLORIDE 500 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Granules India Ltd | METFORMIN HYDROCHLORIDE 1000 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Granules India Ltd | METFORMIN HYDROCHLORIDE 500 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Granules Pharmaceuticals Inc. | METFORMIN HYDROCHLORIDE 500 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Granules Pharmaceuticals Inc. | METFORMIN HYDROCHLORIDE 1000 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Laurus Labs Limited | METFORMIN HYDROCHLORIDE 750 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Laurus Labs Limited | METFORMIN HYDROCHLORIDE 500 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Leading Pharma, LLC | METFORMIN HYDROCHLORIDE 500 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Macleods Pharmaceuticals Limited | METFORMIN HYDROCHLORIDE 500 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Macleods Pharmaceuticals Limited | METFORMIN HYDROCHLORIDE 750 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Macleods Pharmaceuticals Limited | METFORMIN HYDROCHLORIDE 1000 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Marksans Pharma Limited | METFORMIN HYDROCHLORIDE 750 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
Roster from daily NDC Directory diffs — first/last seen dates start July 2026.
DrugDashboards, "Metformin hydrochloride ER — NDC 42291-0824-10," retrieved September 3, 2026, https://drugdashboards.com/drug/42291082410.
Free to cite with attribution — see how the data is put together.