DrugDashboards

Acetylcysteine

Acetylcysteine · ACETYLCYSTEINE 100 mg/mL · Solution · Respiratory (Inhalation) · Cameron Pharmaceuticals

NDC 42494-0435-25 · 25 VIAL in 1 CARTON / 4 mL in 1 VIAL · ANDA · View full market →

The short version

4 companies supply this market — a reasonable cushion if one runs into trouble. Put together: this looks like a healthy supply — the boring kind, which is exactly what you want.

The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.

One drug, every price

The same NDC has different prices depending on who is paying. Units differ between rungs — compare within a rung over time, not rung against rung, unless the units match.

ⓘ How this was built
Data sources
  • CMS NADAC (pharmacy acquisition, weekly)
  • CMS Part B ASP quarterly payment limits
  • CMS Maximum Fair Prices (IRA negotiated, NDC-level)
  • Medicare Part D Spending by Drug (data.cms.gov, name-matched)
  • VA FSS / Big4 federal contract prices (va.gov, twice monthly)
  • ACA Federal Upper Limits + weighted AMP (data.medicaid.gov, monthly)
  • California SB-17 WAC filings (list price, per package)
Method

Each rung is the newest figure for this NDC from one federal price system, shown with its own unit. Part D is matched by drug name because CMS publishes no NDCs there; it is gross spending, before confidential rebates.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

  • Pharmacies pay (NADAC)$2.62per MLinvoice-surveyed acquisition cost · Aug 19, 2026
  • Medicare Part B pays (ASP+6%)$7.27per billing unit (1 GM)HCPCS J7608 · Jul 1, 2026
  • Part D plans paid (avg)$0.9436per dosage unitgross, before rebates — matched by drug name · 2024

Medicare Part D

No Medicare Part D plan in CMS's quarterly files lists this product. That usually means it is discontinued, a repackager's listing, or a product no plan has added to its formulary.

How Part D pricing works →

NADAC price per unit

$0$1.00$2.00$3.00Feb 2026Sep 2026$2.62
8 price points · per MLSource: CMS NADAC

Estimated fill cost

WAC per package, as filed
$212.00
Reported to Texas DSHS · 2026 annual filing · Cameron Pharmaceuticals, LLC

Manufacturer list price as filed — not what pharmacies actually pay after discounts.

Medicare Part B (ASP)

Payment limit per 1 GM
$7.274
HCPCS J7608 · Jul 1, 2026 quarter · typically ASP + 6%

Supply fragility

5Low risk

Some pressure is visible, but not much — here’s everything the score found to count.

  • 4 active manufacturers+5

The score counts pressure that is already visible — fewer makers, shortages, recalls, falling prices. 0 means none of it; 100 means all of it at once. Recomputed daily · as of Sep 3, 2026

90-day shortage risk (model v2)

0.2%chance of a new FDA shortage posting for acetylcysteine (other) in the next 90 days

OAI inspection at a producing facility (24 months) · sole-source market · price up 7% YoY

For scale: the typical drug’s chance is about 0.1% — this one is in ordinary territory.

Backtested statistical model over the whole market, not this package alone. Model details →

Where it's made

Establishments this product's FDA label declares, located via FDA registration data. How we built this →

Regulatory

Application
ANDA214177
TE code
AN
Approval date
Mar 14, 2025
Patents / exclusivity
None on file

Shortage history

No FDA shortage reports for this drug or its presentations.

Recalls (this NDC)

No enforcement reports list this package NDC.

Manufacturers of Acetylcysteine (Solution)

LabelerStrengthFirst seenLast seen
Fresenius Kabi USA, LLCACETYLCYSTEINE 100 mg/mLJul 15, 2026Sep 3, 2026
Fresenius Kabi USA, LLCACETYLCYSTEINE 200 mg/mLJul 15, 2026Sep 3, 2026
Cameron PharmaceuticalsACETYLCYSTEINE 100 mg/mLJul 15, 2026Sep 2, 2026
Cameron PharmaceuticalsACETYLCYSTEINE 200 mg/mLJul 15, 2026Sep 2, 2026
Hospira, Inc.ACETYLCYSTEINE 100 mg/mLJul 15, 2026Sep 2, 2026
Hospira, Inc.ACETYLCYSTEINE 200 mg/mLJul 15, 2026Sep 2, 2026
Somerset Therapeutics, LLCACETYLCYSTEINE 200 mg/mLJul 15, 2026Sep 2, 2026
Somerset Therapeutics, LLCACETYLCYSTEINE 100 mg/mLJul 15, 2026Sep 2, 2026

Roster from daily NDC Directory diffs — first/last seen dates start July 2026.

Cite this page

DrugDashboards, "Acetylcysteine — NDC 42494-0435-25," retrieved September 3, 2026, https://drugdashboards.com/drug/42494043525.

Free to cite with attribution — see how the data is put together.