DrugDashboards

alogliptin and metformin hydrochloride

alogliptin and metformin hydrochloride · ALOGLIPTIN BENZOATE 12.5 mg/1; METFORMIN HYDROCHLORIDE 1000 mg/1 · Tablet, Film Coated · Oral · Padagis Israel Pharmaceuticals Ltd

NDC 45802-0211-72 · 60 TABLET, FILM COATED in 1 BOTTLE · NDA AUTHORIZED GENERIC · View full market →

The short version

5 companies supply this market — a reasonable cushion if one runs into trouble. The price has held steady around $2.49 per unit over the past year. Put together: this looks like a healthy supply — the boring kind, which is exactly what you want.

The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.

One drug, every price

The same NDC has different prices depending on who is paying. Units differ between rungs — compare within a rung over time, not rung against rung, unless the units match.

ⓘ How this was built
Data sources
  • CMS NADAC (pharmacy acquisition, weekly)
  • CMS Part B ASP quarterly payment limits
  • CMS Maximum Fair Prices (IRA negotiated, NDC-level)
  • Medicare Part D Spending by Drug (data.cms.gov, name-matched)
  • VA FSS / Big4 federal contract prices (va.gov, twice monthly)
  • ACA Federal Upper Limits + weighted AMP (data.medicaid.gov, monthly)
  • California SB-17 WAC filings (list price, per package)
Method

Each rung is the newest figure for this NDC from one federal price system, shown with its own unit. Part D is matched by drug name because CMS publishes no NDCs there; it is gross spending, before confidential rebates.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

  • Pharmacies pay (NADAC)$2.49per EAinvoice-surveyed acquisition cost · Aug 19, 2026
  • Part D point of sale (median)$3.11per unitnegotiated price across 82 plans — before rebates · Apr 1, 2026
  • Federal contracts pay (FSS)$1.02per unitPadagis Sourcing Solutions LLC · Jan 1, 202641% of what pharmacies pay — a deeper discount than 90% of drugs with this benchmark

Medicare Part D

All Part D pricing →
ⓘ How this was built
Data sources
  • CMS quarterly Prescription Drug Plan Formulary & Pricing files (SPUF)
Method

Negotiated 30-day point-of-sale unit prices and formulary terms aggregated across every unsuppressed Part D and MA-PD plan for the quarter shown. Point of sale means gross of confidential rebates. CMS publishes one representative NDC per drug concept (RxCUI) rather than every package, so these figures come from CMS's representative package for the same drug — matched on generic name, strength, and dosage form. Estimated from MedPAC's program-wide rebate aggregates (June 2023: DIR = 29% of gross Part D spending; brand rebates ≈ 25–40% of gross, generics minimal). Actual rebates are confidential and vary widely by drug — this is a range, not a fact about this drug.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

Plans pay at point of sale
$3.11per unit
middle half $2.48$3.15 · 82 plans · Apr 1, 2026
Est. net of rebates
≈ $3.11
generic — rebates are minimal, so net ≈ gross
Coverage & restrictions
1%of plans cover it
tier 1 · prior auth 10% · step therapy 0% · qty limit 80%

*No drug-level rebate is public — the estimate applies MedPAC's program-wide brand rebate range to this drug's gross price. Tracked here for 10 quarters since 2024.

NADAC price per unit

$0$2.00$4.00Jul 2016Sep 2026$2.49
111 price points · per EASource: CMS NADAC

Estimated fill cost

#30 count
$74.83
#90 count
$224.48

Estimates: latest NADAC unit price × quantity. Pharmacy acquisition cost only — excludes dispensing fees, markup, and insurance terms.

Medicaid spend (2025)

$4.9M
23,374 prescriptions paid by Medicaid nationally · all Medicaid spend →

Supply fragility

5Low risk

Some pressure is visible, but not much — here’s everything the score found to count.

  • 5 active manufacturers+5

The score counts pressure that is already visible — fewer makers, shortages, recalls, falling prices. 0 means none of it; 100 means all of it at once. Recomputed daily · as of Sep 3, 2026

90-day shortage risk (model v2)

0.1%chance of a new FDA shortage posting for alogliptin and metformin hydrochloride (oral solid) in the next 90 days

sole-source market · price up 3% YoY

For scale: the typical drug’s chance is about 0.1% — this one is in ordinary territory.

Backtested statistical model over the whole market, not this package alone. Model details →

Regulatory

Application
NDA203414
TE code
Approval date
Jan 25, 2013
Patents / exclusivity
4 patents, 2 exclusivities
TypeNumber / codeExpires
exclusivityM-300Jul 27, 2026
exclusivityM-300Jul 27, 2026
patent8900638May 24, 2029
patent8900638May 24, 2029
patent7807689Jun 27, 2028
patent7807689Jun 27, 2028

Shortage history

No FDA shortage reports for this drug or its presentations.

Recalls (this NDC)

No enforcement reports list this package NDC.

Manufacturers of alogliptin and metformin hydrochloride (Tablet, Film Coated)

LabelerStrengthFirst seenLast seen
A-S Medication SolutionsALOGLIPTIN BENZOATE 12.5 mg/1; METFORMIN HYDROCHLORIDE 1000 mg/1Jul 15, 2026Sep 2, 2026
Padagis Israel Pharmaceuticals LtdALOGLIPTIN BENZOATE 12.5 mg/1; METFORMIN HYDROCHLORIDE 500 mg/1Jul 15, 2026Sep 2, 2026
Padagis Israel Pharmaceuticals LtdALOGLIPTIN BENZOATE 12.5 mg/1; METFORMIN HYDROCHLORIDE 1000 mg/1Jul 15, 2026Sep 2, 2026
Takeda GmbHALOGLIPTIN BENZOATE 12.5 mg/1; METFORMIN HYDROCHLORIDE 500 mg/1Jul 15, 2026Sep 2, 2026
Takeda GmbHALOGLIPTIN BENZOATE 12.5 mg/1; METFORMIN HYDROCHLORIDE 1000 mg/1Jul 15, 2026Sep 2, 2026
Takeda Pharmaceuticals America, Inc.ALOGLIPTIN BENZOATE 12.5 mg/1; METFORMIN HYDROCHLORIDE 1000 mg/1Jul 15, 2026Sep 2, 2026
Takeda Pharmaceuticals America, Inc.ALOGLIPTIN BENZOATE 12.5 mg/1; METFORMIN HYDROCHLORIDE 500 mg/1Jul 15, 2026Sep 2, 2026
Takeda Pharmaceuticals Co LTDALOGLIPTIN BENZOATE 12.5 mg/1; METFORMIN HYDROCHLORIDE 500 mg/1Jul 15, 2026Sep 2, 2026
Takeda Pharmaceuticals Co LTDALOGLIPTIN BENZOATE 12.5 mg/1; METFORMIN HYDROCHLORIDE 1000 mg/1Jul 15, 2026Sep 2, 2026

Roster from daily NDC Directory diffs — first/last seen dates start July 2026.

Cite this page

DrugDashboards, "alogliptin and metformin hydrochloride — NDC 45802-0211-72," retrieved September 3, 2026, https://drugdashboards.com/drug/45802021172.

Free to cite with attribution — see how the data is put together.