DrugDashboards

diphenhydramine hcl and zinc acetate

Diphenhydramine Hydrochloride, Zinc Acetate · DIPHENHYDRAMINE HYDROCHLORIDE 2 g/100g; ZINC ACETATE .1 g/100g · Cream · Topical · Padagis Israel Pharmaceuticals Ltd

NDC 45802-0358-03 · 1 TUBE in 1 CARTON / 28 g in 1 TUBE · OTC MONOGRAPH DRUG · View full market →

The short version

20 companies supply this market — deep enough that no single failure threatens the supply. The price has held steady around $0.0570 per gram over the past year. Put together: this looks like a healthy supply — the boring kind, which is exactly what you want.

The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.

Medicare Part D

Medicare Part D does not cover over-the-counter drugs — by law it pays only for products requiring a prescription.

How Part D pricing works →

NADAC price per unit

$0$0.025$0.05$0.075Nov 2013Sep 2026$0.057
155 price points · per GMSource: CMS NADAC

Estimated fill cost

WAC per package, as filed
$2.15
Reported to Texas DSHS · 2025 annual filing · Padagis Israel Pharmaceuticals Ltd

Manufacturer list price as filed — not what pharmacies actually pay after discounts.

Medicaid spend (2025)

$3,963
535 prescriptions paid by Medicaid nationally · all Medicaid spend →

Supply fragility

0Low risk

Nothing here is signaling trouble: several manufacturers, no current shortage, no recent serious recalls, stable pricing. In drug supply, boring is the good outcome.

The score counts pressure that is already visible — fewer makers, shortages, recalls, falling prices. 0 means none of it; 100 means all of it at once. Recomputed daily · as of Sep 3, 2026

90-day shortage risk (model v2)

0.1%chance of a new FDA shortage posting for diphenhydramine hydrochloride and zinc acetate (other) in the next 90 days

sole-source market · price up 2% YoY

For scale: the typical drug’s chance is about 0.1% — this one is in ordinary territory.

Backtested statistical model over the whole market, not this package alone. Model details →

Regulatory

Application
M017
TE code
Approval date
Patents / exclusivity
None on file

Shortage history

No FDA shortage reports for this drug or its presentations.

Recalls (this NDC)

No enforcement reports list this package NDC.

Manufacturers of Diphenhydramine Hydrochloride, Zinc Acetate (Cream)

LabelerStrengthFirst seenLast seen
HyVee IncDIPHENHYDRAMINE HYDROCHLORIDE 2 g/100g; ZINC ACETATE .1 g/100gSep 3, 2026Sep 3, 2026
Amerisource BergenZINC ACETATE .1 g/100g; DIPHENHYDRAMINE HCL 2 g/100gAug 26, 2026Sep 2, 2026
Cardinal Health 110, LLC. dba LeaderDIPHENHYDRAMINE HYDROCHLORIDE 2 g/100g; ZINC ACETATE .1 g/100gJul 15, 2026Sep 2, 2026
CvsDIPHENHYDRAMINE HYDROCHLORIDE 10 mg/g; ZINC ACETATE 1 mg/gJul 15, 2026Sep 2, 2026
CVS PharmacyDIPHENHYDRAMINE HYDROCHLORIDE 2 g/100g; ZINC ACETATE .1 g/100gJul 15, 2026Sep 2, 2026
Discount Drug MartDIPHENHYDRAMINE HYDROCHLORIDE 10 mg/g; ZINC ACETATE 1 mg/gJul 15, 2026Sep 2, 2026
Front Pharmaceutical PlcDIPHENHYDRAMINE HYDROCHLORIDE 2 g/100g; ZINC ACETATE .1 g/100gJul 15, 2026Sep 2, 2026
H E BDIPHENHYDRAMINE HYDROCHLORIDE 2 g/100g; ZINC ACETATE .1 g/100gJul 15, 2026Sep 2, 2026
KrogerZINC ACETATE 1 mg/g; DIPHENHYDRAMINE HYDROCHLORIDE 20 mg/gAug 26, 2026Sep 2, 2026
Kroger CompanyDIPHENHYDRAMINE HYDROCHLORIDE 2 g/100g; ZINC ACETATE .1 g/100gJul 15, 2026Sep 2, 2026
L. Perrigo CompanyDIPHENHYDRAMINE HYDROCHLORIDE 2 g/100g; ZINC ACETATE .1 g/100gJul 15, 2026Sep 2, 2026
Major PharmaceuticalsDIPHENHYDRAMINE HYDROCHLORIDE 2 g/100g; ZINC ACETATE .1 g/100gJul 15, 2026Sep 2, 2026
Meijer Distribution IncDIPHENHYDRAMINE HYDROCHLORIDE 2 g/100g; ZINC ACETATE .1 g/100gJul 15, 2026Sep 2, 2026
Padagis Israel Pharmaceuticals LtdDIPHENHYDRAMINE HYDROCHLORIDE 2 g/100g; ZINC ACETATE .1 g/100gJul 15, 2026Sep 2, 2026
SafewayDIPHENHYDRAMINE HYDROCHLORIDE 2 g/100g; ZINC ACETATE .1 g/100gJul 15, 2026Sep 2, 2026
Strategic Sourcing Services LLCDIPHENHYDRAMINE HYDROCHLORIDE 2 g/100g; ZINC ACETATE .1 g/100gJul 15, 2026Sep 2, 2026
Topco Associates LLCDIPHENHYDRAMINE HYDROCHLORIDE 2 g/100g; ZINC ACETATE .1 g/100gJul 15, 2026Sep 2, 2026
Wal-Mart Stores IncDIPHENHYDRAMINE HYDROCHLORIDE 2 g/100g; ZINC ACETATE .1 g/100gJul 15, 2026Sep 2, 2026
Walgreen CompanyDIPHENHYDRAMINE HYDROCHLORIDE 1 g/100g; ZINC ACETATE .1 g/100gJul 15, 2026Sep 2, 2026
Zhejiang Jingwei Pharmaceutical Co., Ltd.DIPHENHYDRAMINE HYDROCHLORIDE 2 g/100g; ZINC ACETATE .1 g/100gJul 15, 2026Sep 2, 2026
Amerisource BergenZINC ACETATE 2 g/100g; DIPHENHYDRAMINE HCL .1 g/100gJul 22, 2026Aug 19, 2026
KrogerZINC ACETATE 20 mg/g; DIPHENHYDRAMINE HYDROCHLORIDE 1 mg/gJul 22, 2026Aug 19, 2026
Amerisource BergenDIPHENHYDRAMINE HCL 2 g/100g; ZINC ACETATE .1 g/100gJul 15, 2026Jul 15, 2026
KrogerDIPHENHYDRAMINE HYDROCHLORIDE 20 mg/g; ZINC ACETATE 1 mg/gJul 15, 2026Jul 15, 2026

Roster from daily NDC Directory diffs — first/last seen dates start July 2026.

Cite this page

DrugDashboards, "diphenhydramine hcl and zinc acetate — NDC 45802-0358-03," retrieved September 3, 2026, https://drugdashboards.com/drug/45802035803.

Free to cite with attribution — see how the data is put together.