DrugDashboards

Enulose

Lactulose · LACTULOSE 10 g/15mL · Solution · Oral; Rectal · Actavis Pharma, Inc.

NDC 45963-0438-64 · 473 mL in 1 BOTTLE · ANDA · View full market →

The short version

16 companies supply this market — deep enough that no single failure threatens the supply. The price has held steady around $0.0132 per mL over the past year. Put together: this looks like a healthy supply — the boring kind, which is exactly what you want.

The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.

One drug, every price

The same NDC has different prices depending on who is paying. Units differ between rungs — compare within a rung over time, not rung against rung, unless the units match.

ⓘ How this was built
Data sources
  • CMS NADAC (pharmacy acquisition, weekly)
  • CMS Part B ASP quarterly payment limits
  • CMS Maximum Fair Prices (IRA negotiated, NDC-level)
  • Medicare Part D Spending by Drug (data.cms.gov, name-matched)
  • VA FSS / Big4 federal contract prices (va.gov, twice monthly)
  • ACA Federal Upper Limits + weighted AMP (data.medicaid.gov, monthly)
  • California SB-17 WAC filings (list price, per package)
Method

Each rung is the newest figure for this NDC from one federal price system, shown with its own unit. Part D is matched by drug name because CMS publishes no NDCs there; it is gross spending, before confidential rebates.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

  • Pharmacies pay (NADAC)$0.0132per MLinvoice-surveyed acquisition cost · Aug 19, 2026
  • Part D plans paid (avg)$0.0267per dosage unitgross, before rebates — matched by drug name · 2024
  • Part D point of sale (median)$0.0282per unitnegotiated price across 5,484 plans — before rebates · Apr 1, 2026
  • Medicaid generic ceiling (FUL)$0.0151per MLweighted avg manufacturer price $0.0086 · Jun 1, 2022114% of what pharmacies pay — higher than 67% of drugs with this benchmark

Medicare Part D

All Part D pricing →
ⓘ How this was built
Data sources
  • CMS quarterly Prescription Drug Plan Formulary & Pricing files (SPUF)
Method

Negotiated 30-day point-of-sale unit prices and formulary terms aggregated across every unsuppressed Part D and MA-PD plan for the quarter shown. Point of sale means gross of confidential rebates. CMS publishes one representative NDC per drug concept (RxCUI) rather than every package, so these figures come from CMS's representative package for the same drug — matched on generic name, strength, and dosage form. Estimated from MedPAC's program-wide rebate aggregates (June 2023: DIR = 29% of gross Part D spending; brand rebates ≈ 25–40% of gross, generics minimal). Actual rebates are confidential and vary widely by drug — this is a range, not a fact about this drug.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

Plans pay at point of sale
$0.0282per unit
middle half $0.0205$0.0412 · 5,484 plans · Apr 1, 2026
Est. net of rebates
≈ $0.0282
generic — rebates are minimal, so net ≈ gross
Coverage & restrictions
100%of plans cover it
tier 2 · prior auth 0% · step therapy 0% · qty limit 0%

*No drug-level rebate is public — the estimate applies MedPAC's program-wide brand rebate range to this drug's gross price. Tracked here for 10 quarters since 2024.

NADAC price per unit

$0$0.01$0.02Nov 2013Sep 2026$0.0132
154 price points · per ML · dashed = manufacturer avg (WAMP)Source: CMS NADAC

Estimated fill cost

WAC per package, as filed
$7.06
Reported to Texas DSHS · 2026 annual filing · Actavis Pharma, Inc.

Manufacturer list price as filed — not what pharmacies actually pay after discounts.

Medicaid spend (2025)

$1.6M
93,623 prescriptions paid by Medicaid nationally · all Medicaid spend →

Supply fragility

0Low risk

Nothing here is signaling trouble: several manufacturers, no current shortage, no recent serious recalls, stable pricing. In drug supply, boring is the good outcome.

The score counts pressure that is already visible — fewer makers, shortages, recalls, falling prices. 0 means none of it; 100 means all of it at once. Recomputed daily · as of Sep 3, 2026

90-day shortage risk (model v2)

0.2%chance of a new FDA shortage posting for lactulose (other) in the next 90 days

OAI inspection at a producing facility (24 months) · sole-source market · price up 6% YoY

For scale: the typical drug’s chance is about 0.1% — this one is in ordinary territory.

Backtested statistical model over the whole market, not this package alone. Model details →

Regulatory

Application
ANDA090502
TE code
AA
Approval date
Jan 25, 2012
Patents / exclusivity
None on file

Shortage history

No FDA shortage reports for this drug or its presentations.

Recalls (this NDC)

No enforcement reports list this package NDC.

Manufacturers of Lactulose (Solution)

LabelerStrengthFirst seenLast seen
Actavis Pharma, Inc.LACTULOSE 10 g/15mLJul 15, 2026Sep 3, 2026
Apozeal Pharmaceuticals IncLACTULOSE 10 g/15mLJul 15, 2026Sep 3, 2026
American Health PackagingLACTULOSE 10 g/15mLAug 26, 2026Sep 2, 2026
Atlantic Biologicals Corp.LACTULOSE 10 g/15mLJul 15, 2026Sep 2, 2026
Bryant Ranch PrepackLACTULOSE 10 g/15mLJul 15, 2026Sep 2, 2026
Cardinal Health 107, LLCLACTULOSE 20 g/30mLJul 15, 2026Sep 2, 2026
Chartwell Governmental & Specialty RX, LLC.LACTULOSE 10 g/15mLJul 15, 2026Sep 2, 2026
Chartwell Governmental & Specialty RX, LLC.LACTULOSE 20 g/30mLJul 15, 2026Sep 2, 2026
Chartwell RX, LLC.LACTULOSE 10 g/15mLJul 15, 2026Sep 2, 2026
Foxland Pharmaceuticals, Inc.LACTULOSE 20 g/20gJul 15, 2026Sep 2, 2026
Foxland Pharmaceuticals, Inc.LACTULOSE 10 g/10gJul 15, 2026Sep 2, 2026
Fresenius Kabi Austria GmbHLACTULOSE 10 g/15mLJul 15, 2026Sep 2, 2026
Lannett Company, Inc.LACTULOSE 10 g/15mLJul 15, 2026Sep 2, 2026
Proficient Rx LPLACTULOSE 10 g/15mLJul 15, 2026Sep 2, 2026
Sun Pharmaceutical Industries, Inc.LACTULOSE 10 g/15mLJul 15, 2026Sep 2, 2026
Xttrium Laboratories, Inc.LACTULOSE 10 g/15mLJul 15, 2026Sep 2, 2026
Chartwell RX, LLCLACTULOSE 10 g/15mLJul 15, 2026Aug 31, 2026
PAI Holdings, LLC dba PAI PharmaLACTULOSE 20 g/30mLJul 15, 2026Aug 31, 2026
PAI Holdings, LLC dba PAI PharmaLACTULOSE 10 g/15mLJul 15, 2026Aug 31, 2026

Roster from daily NDC Directory diffs — first/last seen dates start July 2026.

Cite this page

DrugDashboards, "Enulose — NDC 45963-0438-64," retrieved September 3, 2026, https://drugdashboards.com/drug/45963043864.

Free to cite with attribution — see how the data is put together.