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Acetaminophen and Ibuprofen

Acetaminophen and Ibuprofen · IBUPROFEN 125 mg/1; ACETAMINOPHEN 250 mg/1 · Tablet, Film Coated · Oral · Amerisource Bergen

NDC 46122-0742-68 · 36 TABLET, FILM COATED in 1 CARTON · ANDA · View full market →

The short version

16 companies supply this market — deep enough that no single failure threatens the supply. The price has held steady around $0.1058 per unit over the past year. Put together: this looks like a healthy supply — the boring kind, which is exactly what you want.

The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.

Medicare Part D

No Medicare Part D plan in CMS's quarterly files lists this product. That usually means it is discontinued, a repackager's listing, or a product no plan has added to its formulary.

How Part D pricing works →

NADAC price per unit

$0$0.05$0.1$0.15Mar 2024Sep 2026$0.1058
31 price points · per EASource: CMS NADAC

Estimated fill cost

#30 count
$3.17
#90 count
$9.52

Estimates: latest NADAC unit price × quantity. Pharmacy acquisition cost only — excludes dispensing fees, markup, and insurance terms.

Supply fragility

0● Low risk

Nothing here is signaling trouble: several manufacturers, no current shortage, no recent serious recalls, stable pricing. In drug supply, boring is the good outcome.

The score counts pressure that is already visible — fewer makers, shortages, recalls, falling prices. 0 means none of it; 100 means all of it at once. Recomputed daily · as of Sep 3, 2026

90-day shortage risk (model v2)

0.1%chance of a new FDA shortage posting for acetaminophen and ibuprofen (oral solid) in the next 90 days

price up 19% YoY · sole-source market

For scale: the typical drug’s chance is about 0.1% — this one is in ordinary territory.

Backtested statistical model over the whole market, not this package alone. Model details →

Is this a "specialty" drug?

There's no legal definition — it meets 1 of 6 public criteria. Why that matters →

  • Part D specialty tier
  • Costs ≥ $950/fill
  • Biologic (BLA)
  • Injectable / infused
  • Orphan-drug exclusivity
  • REMS program · Opioid Analgesic REMS Shared System REMS

Regulatory

Application
ANDA216999
TE code
—
Approval date
Aug 1, 2023
Patents / exclusivity
None on file

Shortage history

No FDA shortage reports for this drug or its presentations.

Recalls (this NDC)

No enforcement reports list this package NDC.

Manufacturers of Acetaminophen and Ibuprofen (Tablet, Film Coated)

LabelerStrengthFirst seenLast seen
Aurohealth LLCACETAMINOPHEN 250 mg/1; IBUPROFEN 125 mg/1Jul 15, 2026Sep 3, 2026
Bionpharma Inc.IBUPROFEN 125 mg/1; ACETAMINOPHEN 250 mg/1Aug 20, 2026Sep 3, 2026
AFT Pharmaceuticals US, Inc.ACETAMINOPHEN 325 mg/1; IBUPROFEN 97.5 mg/1Jul 15, 2026Sep 2, 2026
Amerisource BergenIBUPROFEN 125 mg/1; ACETAMINOPHEN 250 mg/1Aug 26, 2026Sep 2, 2026
Bionpharma Inc.IBUPROFEN 125 mg/1; ACETAMINOPHEN 250 mg/1Aug 26, 2026Sep 2, 2026
Bryant Ranch PrepackACETAMINOPHEN 325 mg/1; IBUPROFEN 97.5 mg/1Aug 5, 2026Sep 2, 2026
CVS PharmacyIBUPROFEN 125 mg/1; ACETAMINOPHEN 250 mg/1Aug 26, 2026Sep 2, 2026
Discount Drug Mart, Inc.IBUPROFEN 125 mg/1; ACETAMINOPHEN 250 mg/1Aug 26, 2026Sep 2, 2026
Dr. Reddy's Labortories IncIBUPROFEN 125 mg/1; ACETAMINOPHEN 250 mg/1Aug 26, 2026Sep 2, 2026
Hikma Pharmaceuticals USA IncACETAMINOPHEN 325 mg/1; IBUPROFEN 97.5 mg/1Jul 15, 2026Sep 2, 2026
Kenvue Brands LLCIBUPROFEN 125 mg/1; ACETAMINOPHEN 250 mg/1Aug 26, 2026Sep 2, 2026
Meijer Distribution IncIBUPROFEN 125 mg/1; ACETAMINOPHEN 250 mg/1Aug 26, 2026Sep 2, 2026
Walgreen CompanyIBUPROFEN 125 mg/1; ACETAMINOPHEN 250 mg/1Aug 26, 2026Sep 2, 2026
Aurobindo Pharma LimitedACETAMINOPHEN 250 mg/1; IBUPROFEN 125 mg/1Jul 15, 2026Aug 31, 2026
Chain Drug Marketing Association Inc.IBUPROFEN 125 mg/1; ACETAMINOPHEN 250 mg/1Aug 26, 2026Aug 31, 2026
Preferred Pharmaceuticals Inc.ACETAMINOPHEN 325 mg/1; IBUPROFEN 97.5 mg/1Jul 15, 2026Aug 31, 2026
Chain Drug Marketing Association Inc.IBUPROFEN 250 mg/1; ACETAMINOPHEN 125 mg/1Jul 22, 2026Aug 22, 2026
Amerisource BergenIBUPROFEN 250 mg/1; ACETAMINOPHEN 125 mg/1Jul 22, 2026Aug 21, 2026
Bionpharma Inc.IBUPROFEN 250 mg/1; ACETAMINOPHEN 125 mg/1Jul 22, 2026Aug 21, 2026
CVS PharmacyIBUPROFEN 250 mg/1; ACETAMINOPHEN 125 mg/1Jul 23, 2026Aug 20, 2026
Bionpharma Inc.IBUPROFEN 250 mg/1; ACETAMINOPHEN 125 mg/1Jul 22, 2026Aug 19, 2026
Discount Drug Mart, Inc.IBUPROFEN 250 mg/1; ACETAMINOPHEN 125 mg/1Jul 22, 2026Aug 19, 2026
Dr. Reddy's Labortories IncIBUPROFEN 250 mg/1; ACETAMINOPHEN 125 mg/1Jul 22, 2026Aug 19, 2026
Kenvue Brands LLCIBUPROFEN 250 mg/1; ACETAMINOPHEN 125 mg/1Jul 22, 2026Aug 19, 2026
Meijer Distribution IncIBUPROFEN 250 mg/1; ACETAMINOPHEN 125 mg/1Jul 22, 2026Aug 19, 2026
Walgreen CompanyIBUPROFEN 250 mg/1; ACETAMINOPHEN 125 mg/1Jul 22, 2026Aug 19, 2026
Chain Drug Marketing Association Inc.ACETAMINOPHEN 250 mg/1; IBUPROFEN 125 mg/1Jul 15, 2026Jul 19, 2026
Amerisource BergenACETAMINOPHEN 250 mg/1; IBUPROFEN 125 mg/1Jul 15, 2026Jul 18, 2026
Bionpharma Inc.ACETAMINOPHEN 250 mg/1; IBUPROFEN 125 mg/1Jul 15, 2026Jul 18, 2026
Bionpharma Inc.ACETAMINOPHEN 250 mg/1; IBUPROFEN 125 mg/1Jul 15, 2026Jul 15, 2026
Discount Drug Mart, Inc.ACETAMINOPHEN 250 mg/1; IBUPROFEN 125 mg/1Jul 15, 2026Jul 15, 2026
Dr. Reddy's Labortories IncACETAMINOPHEN 250 mg/1; IBUPROFEN 125 mg/1Jul 15, 2026Jul 15, 2026
Kenvue Brands LLCACETAMINOPHEN 250 mg/1; IBUPROFEN 125 mg/1Jul 15, 2026Jul 15, 2026
Meijer Distribution IncACETAMINOPHEN 250 mg/1; IBUPROFEN 125 mg/1Jul 15, 2026Jul 15, 2026
Walgreen CompanyACETAMINOPHEN 250 mg/1; IBUPROFEN 125 mg/1Jul 15, 2026Jul 15, 2026

Roster from daily NDC Directory diffs — first/last seen dates start July 2026.

Cite this page

DrugDashboards, "Acetaminophen and Ibuprofen — NDC 46122-0742-68," retrieved September 3, 2026, https://drugdashboards.com/drug/46122074268.

Free to cite with attribution — see how the data is put together.