The short version
38 companies supply this market — deep enough that no single failure threatens the supply.
The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.
Medique Pain Off
Acetaminophen, Aspirin, Caffeine · CAFFEINE 65 mg/1; ACETAMINOPHEN 250 mg/1; ASPIRIN 250 mg/1 · Tablet, Film Coated · Oral · Unifirst First Aid Corporation
NDC 47682-0238-13 · 250 PACKET in 1 BOX / 2 TABLET, FILM COATED in 1 PACKET · OTC MONOGRAPH DRUG · View full market →
Medicare Part D
Medicare Part D does not cover over-the-counter drugs — by law it pays only for products requiring a prescription.
How Part D pricing works →NADAC price per unit
No NADAC pricing on file for this NDC — NADAC covers drugs dispensed by retail community pharmacies.
Supply fragility
Not scored — fragility is computed for NADAC-priced NDCs.
90-day shortage risk (model v2)
0.1%chance of a new FDA shortage posting for acetaminophen, aspirin, caffeine (oral solid) in the next 90 days
sole-source market
For scale: the typical drug’s chance is about 0.1% — this one is in ordinary territory.
Backtested statistical model over the whole market, not this package alone. Model details →
Is this a "specialty" drug?
There's no legal definition — it meets 1 of 6 public criteria. Why that matters →
- Part D specialty tier
- Costs ≥ $950/fill
- Biologic (BLA)
- Injectable / infused
- Orphan-drug exclusivity
- REMS program · Opioid Analgesic REMS Shared System REMS
Regulatory
- Application
- M013
- TE code
- —
- Approval date
- —
- Patents / exclusivity
- None on file
Shortage history
No FDA shortage reports for this drug or its presentations.
Recalls (this NDC)
No enforcement reports list this package NDC.
Manufacturers of Acetaminophen, Aspirin, Caffeine (Tablet, Film Coated)
| Labeler | Strength | First seen | Last seen |
|---|---|---|---|
| Amerisource Bergen | ACETAMINOPHEN 250 mg/1; ASPIRIN 250 mg/1; CAFFEINE 65 mg/1 | Jul 15, 2026 | Sep 3, 2026 |
| Cardinal Health 110, LLC. dba Leader | ACETAMINOPHEN 250 mg/1; ASPIRIN 250 mg/1; CAFFEINE 65 mg/1 | Jul 15, 2026 | Sep 3, 2026 |
| Contract Pharmacal Corp. | ACETAMINOPHEN 250 mg/1; CAFFEINE 65 mg/1; ASPIRIN 250 mg/1 | Aug 20, 2026 | Sep 3, 2026 |
| L. Perrigo Company | ACETAMINOPHEN 250 mg/1; ASPIRIN 250 mg/1; CAFFEINE 65 mg/1 | Jul 15, 2026 | Sep 3, 2026 |
| Meijer Distribution Inc | ACETAMINOPHEN 250 mg/1; ASPIRIN 250 mg/1; CAFFEINE 65 mg/1 | Jul 15, 2026 | Sep 3, 2026 |
| United Natural Foods, Inc. dba UNFI | ACETAMINOPHEN 250 mg/1; ASPIRIN 250 mg/1; CAFFEINE 65 mg/1 | Jul 15, 2026 | Sep 3, 2026 |
| Walgreen Company | ACETAMINOPHEN 250 mg/1; ASPIRIN 250 mg/1; CAFFEINE 65 mg/1 | Jul 15, 2026 | Sep 3, 2026 |
| Amazon.com Services LLC | ACETAMINOPHEN 250 mg/1; ASPIRIN 250 mg/1; CAFFEINE 65 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| American Sales Company | ACETAMINOPHEN 250 mg/1; ASPIRIN 250 mg/1; CAFFEINE 65 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Army And Air Force Exchange Service | ACETAMINOPHEN 250 mg/1; ASPIRIN 250 mg/1; CAFFEINE 65 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Cardinal Health 110, LLC. DBA Leader | ACETAMINOPHEN 250 mg/1; ASPIRIN 250 mg/1; CAFFEINE 65 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Chain Drug Marketing Association, Inc. | ACETAMINOPHEN 250 mg/1; ASPIRIN 250 mg/1; CAFFEINE 65 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| CVS Pharmacy | ACETAMINOPHEN 250 mg/1; ASPIRIN 250 mg/1; CAFFEINE 65 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| CVS Pharmacy, Inc. | CAFFEINE 65 mg/1; ASPIRIN 250 mg/1; ACETAMINOPHEN 250 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| Dolgencorp Inc | ACETAMINOPHEN 250 mg/1; ASPIRIN 250 mg/1; CAFFEINE 65 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Dolgencorp, LLC | ACETAMINOPHEN 250 mg/1; ASPIRIN 250 mg/1; CAFFEINE 65 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Dolgencorp, Llc | ACETAMINOPHEN 250 mg/1; ASPIRIN 250 mg/1; CAFFEINE 65 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| H E B | ACETAMINOPHEN 250 mg/1; ASPIRIN 250 mg/1; CAFFEINE 65 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Haleon US Holdings LLC | ACETAMINOPHEN 250 mg/1; ASPIRIN 250 mg/1; CAFFEINE 65 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| HyVee Inc | ACETAMINOPHEN 250 mg/1; ASPIRIN 250 mg/1; CAFFEINE 65 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| JC World Bell Wholesale Co., Inc | ACETAMINOPHEN 250 mg/1; ASPIRIN 250 mg/1; CAFFEINE 65 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Kobayashi Healthcare International, Inc | ACETAMINOPHEN 250 mg/1; CAFFEINE 65 mg/1; ASPIRIN 250 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| Kroger Company | ACETAMINOPHEN 250 mg/1; ASPIRIN 250 mg/1; CAFFEINE 65 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| L.N.K. International, Inc. | ACETAMINOPHEN 250 mg/1; ASPIRIN 250 mg/1; CAFFEINE 65 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| LEADER/ Cardinal Health 110, Inc. | ASPIRIN 250 mg/1; ACETAMINOPHEN 250 mg/1; CAFFEINE 65 mg/1 | Jul 22, 2026 | Sep 2, 2026 |
| Meijer, Inc. | ACETAMINOPHEN 250 mg/1; ASPIRIN 250 mg/1; CAFFEINE 65 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Navajo Manufacturing Company Inc. | CAFFEINE 65 mg/1; ACETAMINOPHEN 250 mg/1; ASPIRIN 250 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| NuCare Pharmaceuticals,Inc. | ASPIRIN 250 mg/1; CAFFEINE 65 mg/1; ACETAMINOPHEN 250 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| Prodose, Inc. | ACETAMINOPHEN 250 mg/1; ASPIRIN 250 mg/1; CAFFEINE 65 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Proficient Rx LP | ACETAMINOPHEN 250 mg/1; ASPIRIN 250 mg/1; CAFFEINE 65 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Proficient Rx LP | ASPIRIN 250 mg/1; CAFFEINE 65 mg/1; ACETAMINOPHEN 250 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| Publix Super Markets Inc | ACETAMINOPHEN 250 mg/1; ASPIRIN 250 mg/1; CAFFEINE 65 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Rite Aid Corporation | ACETAMINOPHEN 250 mg/1; ASPIRIN 250 mg/1; CAFFEINE 65 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Rugby Laboratories | ASPIRIN 250 mg/1; CAFFEINE 65 mg/1; ACETAMINOPHEN 250 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| Safeway | ACETAMINOPHEN 250 mg/1; ASPIRIN 250 mg/1; CAFFEINE 65 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Sportpharm LLC | ACETAMINOPHEN 250 mg/1; ASPIRIN 250 mg/1; CAFFEINE 65 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Sportpharm LLC | CAFFEINE 65 mg/1; ACETAMINOPHEN 250 mg/1; ASPIRIN 250 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| Strategic Sourcing Services LLC | ACETAMINOPHEN 250 mg/1; ASPIRIN 250 mg/1; CAFFEINE 65 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Target Corporation | ACETAMINOPHEN 250 mg/1; ASPIRIN 250 mg/1; CAFFEINE 65 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Unifirst First Aid Corporation | CAFFEINE 65 mg/1; ACETAMINOPHEN 250 mg/1; ASPIRIN 250 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
Roster from daily NDC Directory diffs — first/last seen dates start July 2026.
Cite this page
DrugDashboards, "Medique Pain Off — NDC 47682-0238-13," retrieved September 3, 2026, https://drugdashboards.com/drug/47682023813.
Free to cite with attribution — see how the data is put together.