The short version
Only one company currently supplies this market — there is no backup if it stumbles.
The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.
Medi First Plus PMS Relief
Acetaminophen, Pamabrom, Pyrilamine maleate · PAMABROM 25 mg/1; PYRILAMINE MALEATE 15 mg/1; ACETAMINOPHEN 500 mg/1 · Tablet, Coated · Oral · Unifirst First Aid Corporation
NDC 47682-0723-36 · 75 PACKET in 1 BOX / 2 TABLET, COATED in 1 PACKET · OTC MONOGRAPH DRUG · View full market →
Medicare Part D
Medicare Part D does not cover over-the-counter drugs — by law it pays only for products requiring a prescription.
How Part D pricing works →NADAC price per unit
No NADAC pricing on file for this NDC — NADAC covers drugs dispensed by retail community pharmacies.
Supply fragility
Not scored — fragility is computed for NADAC-priced NDCs.
90-day shortage risk (model v2)
0.1%chance of a new FDA shortage posting for acetaminophen, pamabrom, pyrilamine maleate (oral solid) in the next 90 days
sole-source market · price up 2% YoY
For scale: the typical drug’s chance is about 0.1% — this one is in ordinary territory.
Backtested statistical model over the whole market, not this package alone. Model details →
Is this a "specialty" drug?
There's no legal definition — it meets 1 of 6 public criteria. Why that matters →
- Part D specialty tier
- Costs ≥ $950/fill
- Biologic (BLA)
- Injectable / infused
- Orphan-drug exclusivity
- REMS program · Opioid Analgesic REMS Shared System REMS
Regulatory
- Application
- M027
- TE code
- —
- Approval date
- —
- Patents / exclusivity
- None on file
Shortage history
No FDA shortage reports for this drug or its presentations.
Recalls (this NDC)
No enforcement reports list this package NDC.
Manufacturers of Acetaminophen, Pamabrom, Pyrilamine maleate (Tablet, Coated)
| Labeler | Strength | First seen | Last seen |
|---|---|---|---|
| Unifirst First Aid Corporation | PAMABROM 25 mg/1; PYRILAMINE MALEATE 15 mg/1; ACETAMINOPHEN 500 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| Unifirst First Aid Corporation | PAMABROM 500 mg/1; PYRILAMINE MALEATE 25 mg/1; ACETAMINOPHEN 15 mg/1 | Jul 22, 2026 | Aug 19, 2026 |
| Unifirst First Aid Corporation | ACETAMINOPHEN 500 mg/1; PAMABROM 25 mg/1; PYRILAMINE MALEATE 15 mg/1 | Jul 15, 2026 | Jul 15, 2026 |
Roster from daily NDC Directory diffs — first/last seen dates start July 2026.
Cite this page
DrugDashboards, "Medi First Plus PMS Relief — NDC 47682-0723-36," retrieved September 3, 2026, https://drugdashboards.com/drug/47682072336.
Free to cite with attribution — see how the data is put together.