DrugDashboards

Taclonex

calcipotriene and betamethasone dipropionate · CALCIPOTRIENE HYDRATE 50 ug/g; BETAMETHASONE DIPROPIONATE .5 mg/g · Suspension · Topical · LEO Pharma Inc.

NDC 50222-0501-06 · 40 CARTON in 1 CASE / 1 BOTTLE in 1 CARTON / 60 g in 1 BOTTLE · NDA · View full market →

The short version

Just 3 companies supply this market — thin enough that a single exit would be felt immediately. The price has held steady around $20.70 per gram over the past year. Put together: this looks like a healthy supply — the boring kind, which is exactly what you want.

The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.

One drug, every price

The same NDC has different prices depending on who is paying. Units differ between rungs — compare within a rung over time, not rung against rung, unless the units match.

ⓘ How this was built
Data sources
  • CMS NADAC (pharmacy acquisition, weekly)
  • CMS Part B ASP quarterly payment limits
  • CMS Maximum Fair Prices (IRA negotiated, NDC-level)
  • Medicare Part D Spending by Drug (data.cms.gov, name-matched)
  • VA FSS / Big4 federal contract prices (va.gov, twice monthly)
  • ACA Federal Upper Limits + weighted AMP (data.medicaid.gov, monthly)
  • California SB-17 WAC filings (list price, per package)
Method

Each rung is the newest figure for this NDC from one federal price system, shown with its own unit. Part D is matched by drug name because CMS publishes no NDCs there; it is gross spending, before confidential rebates.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

  • Pharmacies pay (NADAC)$20.70per GMinvoice-surveyed acquisition cost · Nov 19, 2025
  • Part D plans paid (avg)$21.08per dosage unitgross, before rebates — matched by drug name · 2024
  • Part D point of sale (median)$20.61per unitnegotiated price across 2 plans — before rebates · Jul 1, 2024
  • Federal ceiling (Big4)$910.50per package of 60GMLEO Pharma, Inc. · Jan 1, 2026
  • Medicaid generic ceiling (FUL)$4.17per GMweighted avg manufacturer price $2.3821 · Dec 1, 202320% of what pharmacies pay — a deeper discount than 95% of drugs with this benchmark

Medicare Part D

All Part D pricing →
ⓘ How this was built
Data sources
  • CMS quarterly Prescription Drug Plan Formulary & Pricing files (SPUF)
Method

Negotiated 30-day point-of-sale unit prices and formulary terms aggregated across every unsuppressed Part D and MA-PD plan for the quarter shown. Point of sale means gross of confidential rebates. CMS publishes one representative NDC per drug concept (RxCUI) rather than every package, so these figures come from CMS's representative package for the same drug — matched on generic name, strength, and dosage form. Estimated from MedPAC's program-wide rebate aggregates (June 2023: DIR = 29% of gross Part D spending; brand rebates ≈ 25–40% of gross, generics minimal). Actual rebates are confidential and vary widely by drug — this is a range, not a fact about this drug.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

Plans pay at point of sale
$20.61per unit
middle half $20.61$20.61 · 2 plans · Jul 1, 2024
Est. net of rebates
$12.36–$15.45
brand drug — est. 25-40% rebate off the price at left
Coverage & restrictions
of plans cover it

*No drug-level rebate is public — the estimate applies MedPAC's program-wide brand rebate range to this drug's gross price. Tracked here for 3 quarters since 2024.

NADAC price per unit

$0$10.00$20.00$30.00Jul 2013Nov 2025$20.70
37 price points · per GM · last surveyed Invalid Date · dashed = manufacturer avg (WAMP)Source: CMS NADAC

Estimated fill cost

WAC per package, as filed
$1,302.02
Reported to Texas DSHS · 2026 annual filing · LEO Pharma Inc.

Manufacturer list price as filed — not what pharmacies actually pay after discounts.

Medicaid spend (2025)

$421,697
298 prescriptions paid by Medicaid nationally · all Medicaid spend →

Supply fragility

10Low risk

Some pressure is visible, but not much — here’s everything the score found to count.

  • 3 active manufacturers+10

The score counts pressure that is already visible — fewer makers, shortages, recalls, falling prices. 0 means none of it; 100 means all of it at once. Recomputed daily · as of Sep 3, 2026

90-day shortage risk (model v2)

0.1%chance of a new FDA shortage posting for calcipotriene and betamethasone dipropionate (other) in the next 90 days

sole-source market

For scale: the typical drug’s chance is about 0.1% — this one is in ordinary territory.

Backtested statistical model over the whole market, not this package alone. Model details →

Where it's made

Establishments this product's FDA label declares, located via FDA registration data. How we built this →

Is this a "specialty" drug?

There's no legal definition — it meets 1 of 6 public criteria. Why that matters →

  • Part D specialty tier
  • Costs ≥ $950/fill · avg $2,027.64 per prescription
  • Biologic (BLA)
  • Injectable / infused
  • Orphan-drug exclusivity
  • REMS program

Regulatory

Application
NDA022185
TE code
AB
Approval date
May 9, 2008
Patents / exclusivity
None on file

Shortage history

No FDA shortage reports for this drug or its presentations.

Recalls (this NDC)

  • Class III · TerminatedJan 16, 2017
    LEO PHARMA INCLabeling: Incorrect or missing package insert: the affected product was packaged with an out-of-date package insert (PI) dated February 2014.

Manufacturers of calcipotriene and betamethasone dipropionate (Suspension)

LabelerStrengthFirst seenLast seen
Cosette Pharmaceuticals, Inc.BETAMETHASONE DIPROPIONATE .5 mg/g; CALCIPOTRIENE 50 ug/gJul 15, 2026Sep 2, 2026
LEO Pharma Inc.CALCIPOTRIENE HYDRATE 50 ug/g; BETAMETHASONE DIPROPIONATE .5 mg/gAug 26, 2026Sep 2, 2026
Sun Pharmaceutical Industries, Inc.CALCIPOTRIENE 50 ug/g; BETAMETHASONE DIPROPIONATE 50 mg/gAug 26, 2026Sep 2, 2026
LEO Pharma Inc.CALCIPOTRIENE HYDRATE .5 mg/g; BETAMETHASONE DIPROPIONATE 50 ug/gJul 22, 2026Aug 19, 2026
Sun Pharmaceutical Industries, Inc.CALCIPOTRIENE 50 mg/g; BETAMETHASONE DIPROPIONATE 50 ug/gJul 22, 2026Aug 19, 2026
LEO Pharma Inc.BETAMETHASONE DIPROPIONATE .5 mg/g; CALCIPOTRIENE HYDRATE 50 ug/gJul 15, 2026Jul 15, 2026
Sun Pharmaceutical Industries, Inc.BETAMETHASONE DIPROPIONATE 50 mg/g; CALCIPOTRIENE 50 ug/gJul 15, 2026Jul 15, 2026

Roster from daily NDC Directory diffs — first/last seen dates start July 2026.

Cite this page

DrugDashboards, "Taclonex — NDC 50222-0501-06," retrieved September 3, 2026, https://drugdashboards.com/drug/50222050106.

Free to cite with attribution — see how the data is put together.