The short version
8 companies supply this market — a reasonable cushion if one runs into trouble.
The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.
Daytime, Nighttime Severe Cold and Flu Relief
Acetaminophen, Dextromethorphan HBr, Doxylamine Succinate, Guaifenesin, Phenylephrine HCl · Kit · Cvs Woonsocket Prescription Center, Incorporated
NDC 51316-0647-22 · 1 KIT in 1 CARTON * 8 TABLET, FILM COATED in 1 BLISTER PACK * 8 TABLET, FILM COATED in 1 BLISTER PACK · OTC MONOGRAPH DRUG · View full market →
Medicare Part D
Medicare Part D does not cover over-the-counter drugs — by law it pays only for products requiring a prescription.
How Part D pricing works →NADAC price per unit
No NADAC pricing on file for this NDC — NADAC covers drugs dispensed by retail community pharmacies.
Supply fragility
Not scored — fragility is computed for NADAC-priced NDCs.
Is this a "specialty" drug?
There's no legal definition — it meets 1 of 6 public criteria. Why that matters →
- Part D specialty tier
- Costs ≥ $950/fill
- Biologic (BLA)
- Injectable / infused
- Orphan-drug exclusivity
- REMS program · Opioid Analgesic REMS Shared System REMS
Regulatory
- Application
- M012
- TE code
- —
- Approval date
- —
- Patents / exclusivity
- None on file
Shortage history
No FDA shortage reports for this drug or its presentations.
Recalls (this NDC)
No enforcement reports list this package NDC.
Manufacturers of Acetaminophen, Dextromethorphan HBr, Doxylamine Succinate, Guaifenesin, Phenylephrine HCl (Kit)
| Labeler | Strength | First seen | Last seen |
|---|---|---|---|
| Amazon.com Services LLC | Jul 15, 2026 | Sep 3, 2026 | |
| Army And Air Force Exchange Service | Jul 15, 2026 | Sep 2, 2026 | |
| Costco Wholesale Corporation | Jul 15, 2026 | Sep 2, 2026 | |
| Cvs Woonsocket Prescription Center, Incorporated | Jul 15, 2026 | Sep 2, 2026 | |
| L. Perrigo Company | Jul 15, 2026 | Sep 2, 2026 | |
| Rite Aid Corporation | Jul 15, 2026 | Sep 2, 2026 | |
| Topco Associates LLC | Jul 15, 2026 | Sep 2, 2026 | |
| Walgreen Company | Jul 15, 2026 | Aug 31, 2026 |
Roster from daily NDC Directory diffs — first/last seen dates start July 2026.
Cite this page
DrugDashboards, "Daytime, Nighttime Severe Cold and Flu Relief — NDC 51316-0647-22," retrieved September 3, 2026, https://drugdashboards.com/drug/51316064722.
Free to cite with attribution — see how the data is put together.