The short version
Just 2 companies supply this market — thin enough that a single exit would be felt immediately.
The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.
CVS PHARMACY Nighttime MS Flu Relief
Acetaminophen, Chlorpheniramine Maleate and Dextromethophan HBr · ACETAMINOPHEN 1000 mg/1; CHLORPHENIRAMINE MALEATE 4 mg/1; DEXTROMETHORPHAN HYDROBROMIDE 30 mg/1 · Powder, For Solution · Oral · Cvs Pharmacy
NDC 51316-0945-06 · 6 PACKET in 1 CARTON / 1 POWDER, FOR SOLUTION in 1 PACKET · OTC MONOGRAPH DRUG · View full market →
Medicare Part D
Medicare Part D does not cover over-the-counter drugs — by law it pays only for products requiring a prescription.
How Part D pricing works →NADAC price per unit
No NADAC pricing on file for this NDC — NADAC covers drugs dispensed by retail community pharmacies.
Supply fragility
Not scored — fragility is computed for NADAC-priced NDCs.
Is this a "specialty" drug?
There's no legal definition — it meets 1 of 6 public criteria. Why that matters →
- Part D specialty tier
- Costs ≥ $950/fill
- Biologic (BLA)
- Injectable / infused
- Orphan-drug exclusivity
- REMS program · Opioid Analgesic REMS Shared System REMS
Regulatory
- Application
- M012
- TE code
- —
- Approval date
- —
- Patents / exclusivity
- None on file
Shortage history
No FDA shortage reports for this drug or its presentations.
Recalls (this NDC)
No enforcement reports list this package NDC.
Manufacturers of Acetaminophen, Chlorpheniramine Maleate and Dextromethophan HBr (Powder, For Solution)
| Labeler | Strength | First seen | Last seen |
|---|---|---|---|
| Cvs Pharmacy | ACETAMINOPHEN 1000 mg/1; CHLORPHENIRAMINE MALEATE 4 mg/1; DEXTROMETHORPHAN HYDROBROMIDE 30 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Cvs Pharmacy | ACETAMINOPHEN 1000 mg/1; DEXTROMETHORPHAN HYDROBROMIDE 30 mg/1; CHLORPHENIRAMINE MALEATE 4 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| Cardinal Health 110, Llc. Dba Leader | ACETAMINOPHEN 1000 mg/1; CHLORPHENIRAMINE MALEATE 4 mg/1; DEXTROMETHORPHAN HYDROBROMIDE 30 mg/1 | Jul 19, 2026 | Aug 30, 2026 |
| Cvs Pharmacy | ACETAMINOPHEN 1000 mg/1; DEXTROMETHORPHAN HYDROBROMIDE 4 mg/1; CHLORPHENIRAMINE MALEATE 30 mg/1 | Jul 22, 2026 | Aug 19, 2026 |
Roster from daily NDC Directory diffs — first/last seen dates start July 2026.
Cite this page
DrugDashboards, "CVS PHARMACY Nighttime MS Flu Relief — NDC 51316-0945-06," retrieved September 3, 2026, https://drugdashboards.com/drug/51316094506.
Free to cite with attribution — see how the data is put together.