The short version
Just 2 companies supply this market — thin enough that a single exit would be felt immediately.
The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.
Protamine Sulfate
Protamine Sulfate · PROTAMINE SULFATE 10 mg/mL · Injection, Solution · Intravenous · HF Acquisition Co LLC, DBA HealthFirst
NDC 51662-1414-01 · 5 mL in 1 VIAL, SINGLE-DOSE · ANDA · View full market →
Medicare Part D
No Medicare Part D plan in CMS's quarterly files lists this product. That usually means it is discontinued, a repackager's listing, or a product no plan has added to its formulary.
How Part D pricing works →NADAC price per unit
No NADAC pricing on file for this NDC — NADAC covers drugs dispensed by retail community pharmacies.
Medicare Part B (ASP)
Payment limit per 10 MG
$1.768
HCPCS J2720 · Jul 1, 2026 quarter · typically ASP + 6%
Supply fragility
Not scored — fragility is computed for NADAC-priced NDCs.
Where it's made
- HF Acquisition Co LLCUnited Statesrelabel
Establishments this product's FDA label declares, located via FDA registration data. How we built this →
Is this a "specialty" drug?
There's no legal definition — it meets 1 of 6 public criteria. Why that matters →
- Part D specialty tier
- Costs ≥ $950/fill
- Biologic (BLA)
- Injectable / infused
- Orphan-drug exclusivity
- REMS program
Regulatory
- Application
- ANDA089454
- TE code
- —
- Approval date
- Apr 7, 1987
- Patents / exclusivity
- None on file
Shortage history
No FDA shortage reports for this drug or its presentations.
Recalls (this NDC)
No enforcement reports list this package NDC.
Manufacturers of Protamine Sulfate (Injection, Solution)
| Labeler | Strength | First seen | Last seen |
|---|---|---|---|
| Fresenius Kabi USA, LLC | PROTAMINE SULFATE 10 mg/mL | Jul 15, 2026 | Sep 3, 2026 |
| HF Acquisition Co LLC, DBA HealthFirst | PROTAMINE SULFATE 10 mg/mL | Jul 15, 2026 | Sep 2, 2026 |
Roster from daily NDC Directory diffs — first/last seen dates start July 2026.
Cite this page
DrugDashboards, "Protamine Sulfate — NDC 51662-1414-01," retrieved September 3, 2026, https://drugdashboards.com/drug/51662141401.
Free to cite with attribution — see how the data is put together.