DrugDashboards

Naproxen

Naproxen · NAPROXEN 375 mg/1 · Tablet · Oral · Amneal Pharmaceuticals of New York LLC

NDC 53746-0189-01 · 100 TABLET in 1 BOTTLE · ANDA · View full market →

The short version

23 companies supply this market — deep enough that no single failure threatens the supply. The price is up 9% over the past year, to $0.0784 per unit.

The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.

One drug, every price

The same NDC has different prices depending on who is paying. Units differ between rungs — compare within a rung over time, not rung against rung, unless the units match.

ⓘ How this was built
Data sources
  • CMS NADAC (pharmacy acquisition, weekly)
  • CMS Part B ASP quarterly payment limits
  • CMS Maximum Fair Prices (IRA negotiated, NDC-level)
  • Medicare Part D Spending by Drug (data.cms.gov, name-matched)
  • VA FSS / Big4 federal contract prices (va.gov, twice monthly)
  • ACA Federal Upper Limits + weighted AMP (data.medicaid.gov, monthly)
  • California SB-17 WAC filings (list price, per package)
Method

Each rung is the newest figure for this NDC from one federal price system, shown with its own unit. Part D is matched by drug name because CMS publishes no NDCs there; it is gross spending, before confidential rebates.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

  • Part D plans paid (avg)$0.1692per dosage unitgross, before rebates — matched by drug name · 2024
  • Medicaid generic ceiling (FUL)$0.0747per TABweighted avg manufacturer price $0.0380 · Jun 1, 2020

Medicare Part D

All Part D pricing →

Matched to CMS's representative package for this drug (NDC 65162-0189-10) — same generic, strength, and dosage form. CMS prices one NDC per drug concept, not every package.

ⓘ How this was built
Data sources
  • CMS quarterly Prescription Drug Plan Formulary & Pricing files (SPUF)
Method

Negotiated 30-day point-of-sale unit prices and formulary terms aggregated across every unsuppressed Part D and MA-PD plan for the quarter shown. Point of sale means gross of confidential rebates. CMS publishes one representative NDC per drug concept (RxCUI) rather than every package, so these figures come from CMS's representative package for the same drug — matched on generic name, strength, and dosage form. Estimated from MedPAC's program-wide rebate aggregates (June 2023: DIR = 29% of gross Part D spending; brand rebates ≈ 25–40% of gross, generics minimal). Actual rebates are confidential and vary widely by drug — this is a range, not a fact about this drug.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

Plans pay at point of sale
$0.1205per unit
middle half $0.0738$0.1637 · 5,496 plans · Apr 1, 2026
Est. net of rebates
≈ $0.1205
generic — rebates are minimal, so net ≈ gross
Coverage & restrictions
100%of plans cover it
tier 1 · prior auth 0% · step therapy 0% · qty limit 6%

*No drug-level rebate is public — the estimate applies MedPAC's program-wide brand rebate range to this drug's gross price. Tracked here for 10 quarters since 2024.

NADAC price per unit

$0$0.05$0.1Nov 2013Apr 2020$0.0784
78 price points · per · last surveyed Invalid Date · dashed = manufacturer avg (WAMP)Source: CMS NADAC

Estimated fill cost

WAC per package, as filed
$9.22
Reported to Texas DSHS · 2023 annual filing · Amneal Pharmaceuticals LLC

Manufacturer list price as filed — not what pharmacies actually pay after discounts.

Medicaid spend (2023)

$130
17 prescriptions paid by Medicaid nationally · all Medicaid spend →

Supply fragility

Not scored — fragility is computed for NADAC-priced NDCs.

90-day shortage risk (model v2)

0.1%chance of a new FDA shortage posting for naproxen (oral solid) in the next 90 days

sole-source market

For scale: the typical drug’s chance is about 0.1% — this one is in ordinary territory.

Backtested statistical model over the whole market, not this package alone. Model details →

Where it's made

Establishments this product's FDA label declares, located via FDA registration data. How we built this →

Regulatory

Application
ANDA075927
TE code
AB
Approval date
Dec 18, 2001
Patents / exclusivity
None on file

Shortage history

No FDA shortage reports for this drug or its presentations.

Recalls (this NDC)

No enforcement reports list this package NDC.

Manufacturers of Naproxen (Tablet)

LabelerStrengthFirst seenLast seen
A-S Medication SolutionsNAPROXEN 375 mg/1Jul 15, 2026Sep 3, 2026
A-S Medication SolutionsNAPROXEN 500 mg/1Jul 15, 2026Sep 3, 2026
Advanced Rx of Tennessee, LLCNAPROXEN 375 mg/1Jul 15, 2026Sep 3, 2026
Aphena Pharma Solutions - Tennessee, LLCNAPROXEN 375 mg/1Jul 15, 2026Sep 3, 2026
Aphena Pharma Solutions - Tennessee, LLCNAPROXEN 250 mg/1Jul 15, 2026Sep 3, 2026
Aurobindo Pharma LimitedNAPROXEN 500 mg/1Jul 15, 2026Sep 3, 2026
Bryant Ranch PrepackNAPROXEN 250 mg/1Jul 15, 2026Sep 3, 2026
Bryant Ranch PrepackNAPROXEN 500 mg/1Jul 15, 2026Sep 3, 2026
Coupler LLCNAPROXEN 500 mg/1Jul 15, 2026Sep 3, 2026
NuCare Pharmaceuticals, Inc.NAPROXEN 500 mg/1Jul 15, 2026Sep 3, 2026
NuCare Pharmaceuticals,Inc.NAPROXEN 500 mg/1Jul 15, 2026Sep 3, 2026
PD-Rx Pharmaceuticals, Inc.NAPROXEN 500 mg/1Jul 15, 2026Sep 3, 2026
Preferred Pharmaceuticals Inc.NAPROXEN 500 mg/1Jul 15, 2026Sep 3, 2026
Proficient Rx LPNAPROXEN 250 mg/1Jul 15, 2026Sep 3, 2026
Advanced Rx Pharmacy of Tennessee, LLCNAPROXEN 375 mg/1Jul 15, 2026Sep 2, 2026
Advanced Rx Pharmacy of Tennessee, LLCNAPROXEN 500 mg/1Jul 15, 2026Sep 2, 2026
American Health PackagingNAPROXEN 500 mg/1Jul 15, 2026Sep 2, 2026
Amneal Pharmaceuticals LLCNAPROXEN 250 mg/1Jul 15, 2026Sep 2, 2026
Amneal Pharmaceuticals LLCNAPROXEN 500 mg/1Jul 15, 2026Sep 2, 2026
Amneal Pharmaceuticals LLCNAPROXEN 375 mg/1Jul 15, 2026Sep 2, 2026
Amneal Pharmaceuticals of New York LLCNAPROXEN 500 mg/1Jul 15, 2026Sep 2, 2026
Amneal Pharmaceuticals of New York LLCNAPROXEN 375 mg/1Jul 15, 2026Sep 2, 2026
Amneal Pharmaceuticals of New York LLCNAPROXEN 250 mg/1Jul 15, 2026Sep 2, 2026
Asclemed USA, Inc.NAPROXEN 250 mg/1Jul 15, 2026Sep 2, 2026
Asclemed USA, Inc.NAPROXEN 375 mg/1Jul 15, 2026Sep 2, 2026
Aurobindo Pharma LimitedNAPROXEN 250 mg/1Jul 15, 2026Sep 2, 2026
AvPAKNAPROXEN 250 mg/1Jul 15, 2026Sep 2, 2026
AvPAKNAPROXEN 375 mg/1Jul 15, 2026Sep 2, 2026
Boswell Pharmacy Services LLC d/b/a BPS WholesaleNAPROXEN 500 mg/1Jul 15, 2026Sep 2, 2026
Cameron PharmaceuticalsNAPROXEN 500 mg/1Jul 15, 2026Sep 2, 2026
Cameron PharmaceuticalsNAPROXEN 375 mg/1Jul 15, 2026Sep 2, 2026
Cipla USA Inc.NAPROXEN 500 mg/1Jul 15, 2026Sep 2, 2026
Cipla USA Inc.NAPROXEN 375 mg/1Jul 15, 2026Sep 2, 2026
Cipla USA Inc.NAPROXEN 250 mg/1Jul 15, 2026Sep 2, 2026
Coupler LLCNAPROXEN 250 mg/1Jul 15, 2026Sep 2, 2026
Coupler LLCNAPROXEN 375 mg/1Jul 15, 2026Sep 2, 2026
Direct RxNAPROXEN 500 mg/1Jul 15, 2026Sep 2, 2026
Direct_RxNAPROXEN 375 mg/1Jul 15, 2026Sep 2, 2026
Exelan Pharmaceuticals, Inc.NAPROXEN 250 mg/1Jul 15, 2026Sep 2, 2026
Exelan Pharmaceuticals, Inc.NAPROXEN 375 mg/1Jul 15, 2026Sep 2, 2026

Roster from daily NDC Directory diffs — first/last seen dates start July 2026.

Cite this page

DrugDashboards, "Naproxen — NDC 53746-0189-01," retrieved September 3, 2026, https://drugdashboards.com/drug/53746018901.

Free to cite with attribution — see how the data is put together.