DrugDashboards

Methotrexate

Methotrexate · METHOTREXATE SODIUM 50 mg/2mL · Injection, Solution · Intramuscular; Intrathecal; Intravenous; Subcutaneous · Eugia US LLC

NDC 55150-0510-01 · 1 VIAL, SINGLE-DOSE in 1 CARTON / 2 mL in 1 VIAL, SINGLE-DOSE · ANDA · View full market →

The short version

7 companies supply this market — a reasonable cushion if one runs into trouble. It is in shortage right now — FDA lists the reason as “other”.

The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.

Medicare Part D

No Medicare Part D plan in CMS's quarterly files lists this product. That usually means it is discontinued, a repackager's listing, or a product no plan has added to its formulary.

How Part D pricing works →

NADAC price per unit

No NADAC pricing on file for this NDC — NADAC covers drugs dispensed by retail community pharmacies.

Supply fragility

Not scored — fragility is computed for NADAC-priced NDCs.

90-day shortage risk (model v2)

0.4%chance of a new FDA shortage posting for methotrexate (injectable) in the next 90 days

sterile injectable · sole-source market · price up 1% YoY

For scale: the typical drug’s chance is about 0.1% — this one is 3× that.

Backtested statistical model over the whole market, not this package alone. Model details →

Where it's made

Establishments this product's FDA label declares, located via FDA registration data. How we built this →

Is this a "specialty" drug?

There's no legal definition — it meets 2 of 6 public criteria. Why that matters →

  • Part D specialty tier
  • Costs ≥ $950/fill · avg $1,035.57 per prescription
  • Biologic (BLA)
  • Injectable / infused
  • Orphan-drug exclusivity
  • REMS program

Regulatory

Application
ANDA201529
TE code
AP
Approval date
Mar 29, 2012
Patents / exclusivity
None on file

Shortage history

  • In shortage now — Methotrexate Sodium Preservative Free, Injection, 25 mg/1 mL (NDC 0703-3671-01)Mar 13, 2023
    month 42 — 2× the typical 20-month injectable shortage · model puts 35% odds it resolves within 6 months
  • In shortage now — Methotrexate Sodium Preservative Free, Injection, 25 mg/1 mL (NDC 0703-3675-01)Mar 13, 2023
    Other
    month 42 — 2× the typical 20-month injectable shortage · model puts 35% odds it resolves within 6 months
  • In shortage now — Methotrexate Sodium Preservative Free, Injection, 25 mg/1 mL (NDC 0703-3678-01)Mar 13, 2023
    Other
    month 42 — 2× the typical 20-month injectable shortage · model puts 35% odds it resolves within 6 months
  • In shortage now — Methotrexate Sodium, Injection, 1 g/40 mL (25 mg/mL) (NDC 61703-124-40)Mar 13, 2023
    month 42 — 2× the typical 20-month injectable shortage · model puts 35% odds it resolves within 6 months
  • In shortage now — Methotrexate Sodium, Injection, 1 g/40 mL (25 mg/mL) (NDC 61703-408-25)Mar 13, 2023
    month 42 — 2× the typical 20-month injectable shortage · model puts 35% odds it resolves within 6 months
  • In shortage now — Methotrexate Sodium, Injection, 1 g/40 mL (25 mg/mL) (NDC 61703-408-41)Mar 13, 2023
    month 42 — 2× the typical 20-month injectable shortage · model puts 35% odds it resolves within 6 months
  • In shortage now — Methotrexate Sodium, Injection, 50 mg/2 mL (25 mg/mL) (NDC 61703-350-10)Mar 13, 2023
    month 42 — 2× the typical 20-month injectable shortage · model puts 35% odds it resolves within 6 months
  • In shortage now — Methotrexate Sodium, Injection, 50 mg/2 mL (25 mg/mL) (NDC 61703-350-38)Mar 13, 2023
    month 42 — 2× the typical 20-month injectable shortage · model puts 35% odds it resolves within 6 months

Recalls (this NDC)

No enforcement reports list this package NDC.

Manufacturers of Methotrexate (Injection, Solution)

LabelerStrengthFirst seenLast seen
Alembic Pharmaceuticals Inc.METHOTREXATE SODIUM 25 mg/mLJul 15, 2026Sep 3, 2026
Alembic Pharmaceuticals LimitedMETHOTREXATE SODIUM 25 mg/mLJul 15, 2026Sep 3, 2026
Hospira, Inc.METHOTREXATE SODIUM 25 mg/mLJul 15, 2026Sep 3, 2026
Antares Pharma, Inc.METHOTREXATE 25 mg/.4mLJul 15, 2026Sep 2, 2026
Antares Pharma, Inc.METHOTREXATE 10 mg/.4mLJul 15, 2026Sep 2, 2026
Antares Pharma, Inc.METHOTREXATE 12.5 mg/.4mLJul 15, 2026Sep 2, 2026
Antares Pharma, Inc.METHOTREXATE 17.5 mg/.4mLJul 15, 2026Sep 2, 2026
Antares Pharma, Inc.METHOTREXATE 15 mg/.4mLJul 15, 2026Sep 2, 2026
Antares Pharma, Inc.METHOTREXATE 20 mg/.4mLJul 15, 2026Sep 2, 2026
Antares Pharma, Inc.METHOTREXATE 22.5 mg/.4mLJul 15, 2026Sep 2, 2026
Eugia US LLCMETHOTREXATE SODIUM 200 mg/8mLJul 15, 2026Sep 2, 2026
Eugia US LLCMETHOTREXATE SODIUM 250 mg/10mLJul 15, 2026Sep 2, 2026
Eugia US LLCMETHOTREXATE SODIUM 100 mg/4mLJul 15, 2026Sep 2, 2026
Eugia US LLCMETHOTREXATE SODIUM 50 mg/2mLJul 15, 2026Sep 2, 2026
Medexus Pharma Inc.METHOTREXATE SODIUM 7.5 mg/.15mLJul 15, 2026Sep 2, 2026
Medexus Pharma Inc.METHOTREXATE SODIUM 10 mg/.2mLJul 15, 2026Sep 2, 2026
Medexus Pharma Inc.METHOTREXATE SODIUM 12.5 mg/.25mLJul 15, 2026Sep 2, 2026
Medexus Pharma Inc.METHOTREXATE SODIUM 15 mg/.3mLJul 15, 2026Sep 2, 2026
Medexus Pharma Inc.METHOTREXATE SODIUM 17.5 mg/.35mLJul 15, 2026Sep 2, 2026
Medexus Pharma Inc.METHOTREXATE SODIUM 20 mg/.4mLJul 15, 2026Sep 2, 2026
Medexus Pharma Inc.METHOTREXATE SODIUM 22.5 mg/.45mLJul 15, 2026Sep 2, 2026
Medexus Pharma Inc.METHOTREXATE SODIUM 25 mg/.5mLJul 15, 2026Sep 2, 2026
Medexus Pharma Inc.METHOTREXATE SODIUM 30 mg/.6mLJul 15, 2026Sep 2, 2026
Teva Parenteral Medicines, Inc.METHOTREXATE SODIUM 25 mg/mLJul 15, 2026Aug 31, 2026

Roster from daily NDC Directory diffs — first/last seen dates start July 2026.

Cite this page

DrugDashboards, "Methotrexate — NDC 55150-0510-01," retrieved September 3, 2026, https://drugdashboards.com/drug/55150051001.

Free to cite with attribution — see how the data is put together.