The short version
11 companies supply this market — deep enough that no single failure threatens the supply.
The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.
Acetaminophen, Aspirin and Caffeine
Acetaminophen, Aspirin and Caffeine · ASPIRIN 250 mg/1; CAFFEINE 65 mg/1; ACETAMINOPHEN 250 mg/1 · Tablet · Oral · Family Dollar
NDC 55319-0680-10 · 100 TABLET in 1 BOTTLE · ANDA · View full market →
Medicare Part D
No Medicare Part D plan in CMS's quarterly files lists this product. That usually means it is discontinued, a repackager's listing, or a product no plan has added to its formulary.
How Part D pricing works →NADAC price per unit
No NADAC pricing on file for this NDC — NADAC covers drugs dispensed by retail community pharmacies.
Supply fragility
Not scored — fragility is computed for NADAC-priced NDCs.
90-day shortage risk (model v2)
0.1%chance of a new FDA shortage posting for acetaminophen, aspirin, caffeine (oral solid) in the next 90 days
sole-source market
For scale: the typical drug’s chance is about 0.1% — this one is in ordinary territory.
Backtested statistical model over the whole market, not this package alone. Model details →
Is this a "specialty" drug?
There's no legal definition — it meets 1 of 6 public criteria. Why that matters →
- Part D specialty tier
- Costs ≥ $950/fill
- Biologic (BLA)
- Injectable / infused
- Orphan-drug exclusivity
- REMS program · Opioid Analgesic REMS Shared System REMS
Regulatory
- Application
- ANDA214039
- TE code
- —
- Approval date
- Feb 23, 2021
- Patents / exclusivity
- None on file
Shortage history
No FDA shortage reports for this drug or its presentations.
Recalls (this NDC)
No enforcement reports list this package NDC.
Manufacturers of Acetaminophen, Aspirin and Caffeine (Tablet)
| Labeler | Strength | First seen | Last seen |
|---|---|---|---|
| Aaa Pharmaceutical, Inc. | ACETAMINOPHEN 250 mg/1; ASPIRIN 250 mg/1; CAFFEINE 65 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Chain Drug Marketing Association, Inc. | ACETAMINOPHEN 250 mg/1; ASPIRIN 250 mg/1; CAFFEINE 65 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Discount Drug Mart | ACETAMINOPHEN 250 mg/1; ASPIRIN 250 mg/1; CAFFEINE 65 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Family Dollar | ASPIRIN 250 mg/1; CAFFEINE 65 mg/1; ACETAMINOPHEN 250 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| Fsa Store Inc. | ACETAMINOPHEN 250 mg/1; ASPIRIN 250 mg/1; CAFFEINE 65 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Granules India Ltd | ACETAMINOPHEN 250 mg/1; ASPIRIN 250 mg/1; CAFFEINE 65 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Harris Teeter | ACETAMINOPHEN 250 mg/1; ASPIRIN 250 mg/1; CAFFEINE 65 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Publix Super Markets Inc | ACETAMINOPHEN 250 mg/1; ASPIRIN 250 mg/1; CAFFEINE 65 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Rising Pharma Holdings, Inc. | ACETAMINOPHEN 250 mg/1; ASPIRIN 250 mg/1; CAFFEINE 65 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Safeway, Inc | ACETAMINOPHEN 250 mg/1; ASPIRIN 250 mg/1; CAFFEINE 65 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Safrel Pharmaceuticals, LLC. | ACETAMINOPHEN 250 mg/1; ASPIRIN 250 mg/1; CAFFEINE 65 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Family Dollar | ASPIRIN 250 mg/1; CAFFEINE 250 mg/1; ACETAMINOPHEN 65 mg/1 | Jul 22, 2026 | Aug 19, 2026 |
| Family Dollar | ACETAMINOPHEN 250 mg/1; ASPIRIN 250 mg/1; CAFFEINE 65 mg/1 | Jul 15, 2026 | Jul 15, 2026 |
Roster from daily NDC Directory diffs — first/last seen dates start July 2026.
Cite this page
DrugDashboards, "Acetaminophen, Aspirin and Caffeine — NDC 55319-0680-10," retrieved September 3, 2026, https://drugdashboards.com/drug/55319068010.
Free to cite with attribution — see how the data is put together.