The short version
Only one company currently supplies this market — there is no backup if it stumbles.
The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.
ANTIGRIP Nighttime
Acetaminophen, Dextromethorphan HBr, Doxylamine succinate, Phenylephrine HCL · DOXYLAMINE SUCCINATE 6.25 mg/1; ACETAMINOPHEN 325 mg/1; DEXTROMETHORPHAN HYDROBROMIDE 10 mg/1; PHENYLEPHRINE HYDROCHLORIDE 5 mg/1 · Powder, For Solution · Oral · Pharmadel LLC
NDC 55758-0382-18 · 18 POUCH in 1 CARTON / 1 POWDER, FOR SOLUTION in 1 POUCH · OTC MONOGRAPH DRUG · View full market →
Medicare Part D
Medicare Part D does not cover over-the-counter drugs — by law it pays only for products requiring a prescription.
How Part D pricing works →NADAC price per unit
No NADAC pricing on file for this NDC — NADAC covers drugs dispensed by retail community pharmacies.
Supply fragility
Not scored — fragility is computed for NADAC-priced NDCs.
90-day shortage risk (model v2)
0.1%chance of a new FDA shortage posting for acetaminophen, dextromethorphan hbr, doxylamine succinate, phenylephrine hcl (other) in the next 90 days
sole-source market
For scale: the typical drug’s chance is about 0.1% — this one is in ordinary territory.
Backtested statistical model over the whole market, not this package alone. Model details →
Is this a "specialty" drug?
There's no legal definition — it meets 1 of 6 public criteria. Why that matters →
- Part D specialty tier
- Costs ≥ $950/fill
- Biologic (BLA)
- Injectable / infused
- Orphan-drug exclusivity
- REMS program · Opioid Analgesic REMS Shared System REMS
Regulatory
- Application
- M012
- TE code
- —
- Approval date
- —
- Patents / exclusivity
- None on file
Shortage history
No FDA shortage reports for this drug or its presentations.
Recalls (this NDC)
No enforcement reports list this package NDC.
Manufacturers of Acetaminophen, Dextromethorphan HBr, Doxylamine succinate, Phenylephrine HCL (Powder, For Solution)
| Labeler | Strength | First seen | Last seen |
|---|---|---|---|
| Pharmadel LLC | DOXYLAMINE SUCCINATE 6.25 mg/1; ACETAMINOPHEN 325 mg/1; DEXTROMETHORPHAN HYDROBROMIDE 10 mg/1; PHENYLEPHRINE HYDROCHLORIDE 5 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| Pharmadel LLC | DOXYLAMINE SUCCINATE 325 mg/1; ACETAMINOPHEN 10 mg/1; DEXTROMETHORPHAN HYDROBROMIDE 6.25 mg/1; PHENYLEPHRINE HYDROCHLORIDE 5 mg/1 | Jul 22, 2026 | Aug 19, 2026 |
| Pharmadel LLC | ACETAMINOPHEN 325 mg/1; DEXTROMETHORPHAN HYDROBROMIDE 10 mg/1; DOXYLAMINE SUCCINATE 6.25 mg/1; PHENYLEPHRINE HYDROCHLORIDE 5 mg/1 | Jul 15, 2026 | Jul 15, 2026 |
Roster from daily NDC Directory diffs — first/last seen dates start July 2026.
Cite this page
DrugDashboards, "ANTIGRIP Nighttime — NDC 55758-0382-18," retrieved September 3, 2026, https://drugdashboards.com/drug/55758038218.
Free to cite with attribution — see how the data is put together.