DrugDashboards

Codeine-Guaifenesin

Codeine Phosphate and Guaifenesin · CODEINE PHOSPHATE 10 mg/5mL; GUAIFENESIN 100 mg/5mL · Solution · Oral · Method Pharmaceuticals, LLC

NDC 58657-0500-04 · 120 mL in 1 BOTTLE · OTC MONOGRAPH DRUG · View full market →

The short version

6 companies supply this market — a reasonable cushion if one runs into trouble. The price has held steady around $0.0575 per mL over the past year. Put together: this looks like a healthy supply — the boring kind, which is exactly what you want.

The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.

One drug, every price

The same NDC has different prices depending on who is paying. Units differ between rungs — compare within a rung over time, not rung against rung, unless the units match.

ⓘ How this was built
Data sources
  • CMS NADAC (pharmacy acquisition, weekly)
  • CMS Part B ASP quarterly payment limits
  • CMS Maximum Fair Prices (IRA negotiated, NDC-level)
  • Medicare Part D Spending by Drug (data.cms.gov, name-matched)
  • VA FSS / Big4 federal contract prices (va.gov, twice monthly)
  • ACA Federal Upper Limits + weighted AMP (data.medicaid.gov, monthly)
  • California SB-17 WAC filings (list price, per package)
Method

Each rung is the newest figure for this NDC from one federal price system, shown with its own unit. Part D is matched by drug name because CMS publishes no NDCs there; it is gross spending, before confidential rebates.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

  • Pharmacies pay (NADAC)$0.0575per MLinvoice-surveyed acquisition cost · Aug 19, 2026
  • Part D plans paid (avg)$0.0317per dosage unitgross, before rebates — matched by drug name · 2024

Medicare Part D

Medicare Part D does not cover over-the-counter drugs — by law it pays only for products requiring a prescription.

How Part D pricing works →

NADAC price per unit

$0$0.025$0.05$0.075Apr 2015Sep 2026$0.0575
99 price points · per MLSource: CMS NADAC

Medicaid spend (2025)

$40,877
2,603 prescriptions paid by Medicaid nationally · all Medicaid spend →

Supply fragility

0Low risk

Nothing here is signaling trouble: several manufacturers, no current shortage, no recent serious recalls, stable pricing. In drug supply, boring is the good outcome.

The score counts pressure that is already visible — fewer makers, shortages, recalls, falling prices. 0 means none of it; 100 means all of it at once. Recomputed daily · as of Sep 3, 2026

90-day shortage risk (model v2)

0.1%chance of a new FDA shortage posting for guaifenesin and codeine phosphate (other) in the next 90 days

sole-source market · price up 5% YoY

For scale: the typical drug’s chance is about 0.1% — this one is in ordinary territory.

Backtested statistical model over the whole market, not this package alone. Model details →

Regulatory

Application
M012
TE code
Approval date
Patents / exclusivity
None on file

Shortage history

No FDA shortage reports for this drug or its presentations.

Recalls (this NDC)

  • Class II · TerminatedDec 12, 2017
    Woodfield Pharmaceutical, LLCMicrobial Contamination of Non-Sterile Products: potentially contamination with the bacteria Burkholderia cepacia

Manufacturers of Codeine Phosphate and Guaifenesin (Solution)

LabelerStrengthFirst seenLast seen
A-S Medication SolutionsCODEINE PHOSPHATE 10 mg/5mL; GUAIFENESIN 100 mg/5mLJul 15, 2026Sep 2, 2026
Bryant Ranch PrepackCODEINE PHOSPHATE 10 mg/5mL; GUAIFENESIN 100 mg/5mLJul 15, 2026Sep 2, 2026
Method Pharmaceuticals, LLCCODEINE PHOSPHATE 10 mg/5mL; GUAIFENESIN 100 mg/5mLJul 15, 2026Sep 2, 2026
NuCare Pharmaceuticals,Inc.CODEINE PHOSPHATE 10 mg/5mL; GUAIFENESIN 100 mg/5mLJul 15, 2026Sep 2, 2026
Proficient Rx LPCODEINE PHOSPHATE 10 mg/5mL; GUAIFENESIN 100 mg/5mLJul 15, 2026Sep 2, 2026
Westminster Pharmaceuticals, LLCCODEINE PHOSPHATE 10 mg/5mL; GUAIFENESIN 100 mg/5mLJul 15, 2026Sep 2, 2026

Roster from daily NDC Directory diffs — first/last seen dates start July 2026.

Cite this page

DrugDashboards, "Codeine-Guaifenesin — NDC 58657-0500-04," retrieved September 3, 2026, https://drugdashboards.com/drug/58657050004.

Free to cite with attribution — see how the data is put together.