DrugDashboards

cyproheptadine hydrochloride solution

Cyproheptadine Hydrochloride · CYPROHEPTADINE 2 mg/5mL · Solution · Oral · Method Pharmaceuticals, LLC

NDC 58657-0697-16 · 473 mL in 1 BOTTLE, GLASS · ANDA · View full market →

The short version

5 companies supply this market — a reasonable cushion if one runs into trouble. The price has held steady around $0.0412 per mL over the past year. Put together: this looks like a healthy supply — the boring kind, which is exactly what you want.

The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.

One drug, every price

The same NDC has different prices depending on who is paying. Units differ between rungs — compare within a rung over time, not rung against rung, unless the units match.

ⓘ How this was built
Data sources
  • CMS NADAC (pharmacy acquisition, weekly)
  • CMS Part B ASP quarterly payment limits
  • CMS Maximum Fair Prices (IRA negotiated, NDC-level)
  • Medicare Part D Spending by Drug (data.cms.gov, name-matched)
  • VA FSS / Big4 federal contract prices (va.gov, twice monthly)
  • ACA Federal Upper Limits + weighted AMP (data.medicaid.gov, monthly)
  • California SB-17 WAC filings (list price, per package)
Method

Each rung is the newest figure for this NDC from one federal price system, shown with its own unit. Part D is matched by drug name because CMS publishes no NDCs there; it is gross spending, before confidential rebates.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

  • Pharmacies pay (NADAC)$0.0412per MLinvoice-surveyed acquisition cost · May 20, 2026
  • Medicaid generic ceiling (FUL)$0.0411per MLweighted avg manufacturer price $0.0191 · Jun 1, 2026100% of what pharmacies pay — a deeper discount than 90% of drugs with this benchmark

Medicare Part D

No Medicare Part D plan in CMS's quarterly files lists this product. That usually means it is discontinued, a repackager's listing, or a product no plan has added to its formulary.

How Part D pricing works →

NADAC price per unit

$0$0.02$0.04$0.06May 2025Sep 2026$0.0412
14 price points · per ML · held since Invalid Date · dashed = manufacturer avg (WAMP)Source: CMS NADAC

Medicaid spend (2025)

$396
37 prescriptions paid by Medicaid nationally · all Medicaid spend →

Supply fragility

5Low risk

Some pressure is visible, but not much — here’s everything the score found to count.

  • 5 active manufacturers+5

The score counts pressure that is already visible — fewer makers, shortages, recalls, falling prices. 0 means none of it; 100 means all of it at once. Recomputed daily · as of Sep 3, 2026

90-day shortage risk (model v2)

0.1%chance of a new FDA shortage posting for cyproheptadine hydrochloride (other) in the next 90 days

sole-source market · 1 Class I/II recall(s) in 12 months · price up 2% YoY

For scale: the typical drug’s chance is about 0.1% — this one is in ordinary territory.

Backtested statistical model over the whole market, not this package alone. Model details →

Regulatory

Application
ANDA209108
TE code
AA
Approval date
Oct 16, 2018
Patents / exclusivity
None on file

Shortage history

No FDA shortage reports for this drug or its presentations.

Recalls (this NDC)

No enforcement reports list this package NDC.

Manufacturers of Cyproheptadine Hydrochloride (Solution)

LabelerStrengthFirst seenLast seen
Atlantic Biologicals Corp.CYPROHEPTADINE HYDROCHLORIDE 2 mg/5mLAug 6, 2026Sep 3, 2026
Quagen Pharmaceuticals LlcCYPROHEPTADINE HYDROCHLORIDE 2 mg/5mLJul 15, 2026Sep 3, 2026
Bryant Ranch PrepackCYPROHEPTADINE HYDROCHLORIDE 2 mg/5mLJul 15, 2026Sep 2, 2026
Method Pharmaceuticals, LLCCYPROHEPTADINE 2 mg/5mLJul 15, 2026Sep 2, 2026
Patrin Pharma, Inc.CYPROHEPTADINE 2 mg/5mLJul 15, 2026Sep 2, 2026

Roster from daily NDC Directory diffs — first/last seen dates start July 2026.

Cite this page

DrugDashboards, "cyproheptadine hydrochloride solution — NDC 58657-0697-16," retrieved September 3, 2026, https://drugdashboards.com/drug/58657069716.

Free to cite with attribution — see how the data is put together.