DrugDashboards

Zonegran

Zonisamide · ZONISAMIDE 25 mg/1 · Capsule · Oral · Advanz Pharma (US) Corp.

NDC 59212-0681-10 · 100 CAPSULE in 1 BOTTLE · NDA · View full market →

The short version

21 companies supply this market — deep enough that no single failure threatens the supply. The price is up 25% over the past year, to $12.31 per unit.

The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.

One drug, every price

The same NDC has different prices depending on who is paying. Units differ between rungs — compare within a rung over time, not rung against rung, unless the units match.

ⓘ How this was built
Data sources
  • CMS NADAC (pharmacy acquisition, weekly)
  • CMS Part B ASP quarterly payment limits
  • CMS Maximum Fair Prices (IRA negotiated, NDC-level)
  • Medicare Part D Spending by Drug (data.cms.gov, name-matched)
  • VA FSS / Big4 federal contract prices (va.gov, twice monthly)
  • ACA Federal Upper Limits + weighted AMP (data.medicaid.gov, monthly)
  • California SB-17 WAC filings (list price, per package)
Method

Each rung is the newest figure for this NDC from one federal price system, shown with its own unit. Part D is matched by drug name because CMS publishes no NDCs there; it is gross spending, before confidential rebates.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

  • Part D plans paid (avg)$21.43per dosage unitgross, before rebates — matched by drug name · 2024
  • Part D point of sale (median)$18.43per unitnegotiated price across 2 plans — before rebates · Apr 1, 2026
  • Federal ceiling (Big4)$12.83per unitAmdipharm Limited · Jan 1, 2026
  • Medicaid generic ceiling (FUL)$0.1058per CAPweighted avg manufacturer price $0.0429 · Mar 1, 2019

Medicare Part D

All Part D pricing →
ⓘ How this was built
Data sources
  • CMS quarterly Prescription Drug Plan Formulary & Pricing files (SPUF)
Method

Negotiated 30-day point-of-sale unit prices and formulary terms aggregated across every unsuppressed Part D and MA-PD plan for the quarter shown. Point of sale means gross of confidential rebates. CMS publishes one representative NDC per drug concept (RxCUI) rather than every package, so these figures come from CMS's representative package for the same drug — matched on generic name, strength, and dosage form. Estimated from MedPAC's program-wide rebate aggregates (June 2023: DIR = 29% of gross Part D spending; brand rebates ≈ 25–40% of gross, generics minimal). Actual rebates are confidential and vary widely by drug — this is a range, not a fact about this drug.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

Plans pay at point of sale
$18.43per unit
middle half $18.38$18.48 · 2 plans · Apr 1, 2026
Est. net of rebates
$11.06–$13.82
brand drug — est. 25-40% rebate off the price at left
Coverage & restrictions
0%of plans cover it
tier 1 · prior auth 0% · step therapy 0% · qty limit 0%

*No drug-level rebate is public — the estimate applies MedPAC's program-wide brand rebate range to this drug's gross price. Tracked here for 10 quarters since 2024.

NADAC price per unit

$0$5.00$10.00$15.00Aug 2016Sep 2017$12.31
3 price points · per · last surveyed Invalid Date · dashed = manufacturer avg (WAMP)Source: CMS NADAC

Estimated fill cost

WAC per package, as filed
$1,808.77
Reported to Texas DSHS · 2026 annual filing · Advanz Pharma (US) Corp

Manufacturer list price as filed — not what pharmacies actually pay after discounts.

Supply fragility

Not scored — fragility is computed for NADAC-priced NDCs.

90-day shortage risk (model v2)

0.2%chance of a new FDA shortage posting for zonisamide (oral solid) in the next 90 days

OAI inspection at a producing facility (24 months) · sole-source market

For scale: the typical drug’s chance is about 0.1% — this one is in ordinary territory.

Backtested statistical model over the whole market, not this package alone. Model details →

Where it's made

Establishments this product's FDA label declares, located via FDA registration data. How we built this →

Is this a "specialty" drug?

There's no legal definition — it meets 1 of 6 public criteria. Why that matters →

  • Part D specialty tier · median tier 1 across plans
  • Costs ≥ $950/fill · avg $4,366.33 per prescription
  • Biologic (BLA)
  • Injectable / infused
  • Orphan-drug exclusivity
  • REMS program

Regulatory

Application
NDA020789
TE code
AB
Approval date
Mar 27, 2000
Patents / exclusivity
None on file

Shortage history

No FDA shortage reports for this drug or its presentations.

Recalls (this NDC)

No enforcement reports list this package NDC.

Manufacturers of Zonisamide (Capsule)

LabelerStrengthFirst seenLast seen
Aurobindo Pharma LimitedZONISAMIDE 50 mg/1Jul 15, 2026Sep 3, 2026
Bryant Ranch PrepackZONISAMIDE 50 mg/1Jul 16, 2026Sep 3, 2026
Bryant Ranch PrepackZONISAMIDE 25 mg/1Jul 15, 2026Sep 3, 2026
Bryant Ranch PrepackZONISAMIDE 100 mg/1Jul 15, 2026Sep 3, 2026
Proficient Rx LPZONISAMIDE 100 mg/1Jul 15, 2026Sep 3, 2026
Remedyrepack Inc.ZONISAMIDE 100 mg/1Jul 15, 2026Sep 3, 2026
Skyepharma Production SASZONISAMIDE .3333 kg/kgJul 15, 2026Sep 3, 2026
Advanced Rx of Tennessee, LLCZONISAMIDE 100 mg/1Jul 15, 2026Sep 2, 2026
Advanced Rx Pharmacy of Tennessee, LLCZONISAMIDE 100 mg/1Jul 15, 2026Sep 2, 2026
Advanz Pharma (US) Corp.ZONISAMIDE 100 mg/1Jul 15, 2026Sep 2, 2026
Advanz Pharma (US) Corp.ZONISAMIDE 25 mg/1Jul 15, 2026Sep 2, 2026
American Health PackagingZONISAMIDE 100 mg/1Jul 15, 2026Sep 2, 2026
Aurobindo Pharma LimitedZONISAMIDE 25 mg/1Jul 15, 2026Sep 2, 2026
AvPAKZONISAMIDE 100 mg/1Jul 15, 2026Sep 2, 2026
BluePoint LaboratoriesZONISAMIDE 100 mg/1Jul 15, 2026Sep 2, 2026
BluePoint LaboratoriesZONISAMIDE 25 mg/1Jul 15, 2026Sep 2, 2026
BluePoint LaboratoriesZONISAMIDE 50 mg/1Jul 15, 2026Sep 2, 2026
Cipla USA Inc.ZONISAMIDE 100 mg/1Jul 15, 2026Sep 2, 2026
Exelan Pharmaceuticals, Inc.ZONISAMIDE 25 mg/1Jul 15, 2026Sep 2, 2026
Exelan Pharmaceuticals, Inc.ZONISAMIDE 100 mg/1Jul 15, 2026Sep 2, 2026
Exelan Pharmaceuticals, Inc.ZONISAMIDE 50 mg/1Jul 15, 2026Sep 2, 2026
Glenmark Pharmaceuticals Inc., USAZONISAMIDE 50 mg/1Jul 15, 2026Sep 2, 2026
Glenmark Pharmaceuticals Inc., USAZONISAMIDE 100 mg/1Jul 15, 2026Sep 2, 2026
Glenmark Pharmaceuticals Inc., USAZONISAMIDE 25 mg/1Jul 15, 2026Sep 2, 2026
NCS HealthCare of KY, LLC dba Vangard LabsZONISAMIDE 100 mg/1Jul 15, 2026Sep 2, 2026
Preferred Pharmaceuticals IncZONISAMIDE 100 mg/1Jul 15, 2026Sep 2, 2026
Preferred Pharmaceuticals, Inc.ZONISAMIDE 100 mg/1Jul 15, 2026Sep 2, 2026
Remedyrepack Inc.ZONISAMIDE 50 mg/1Jul 15, 2026Sep 2, 2026
Remedyrepack Inc.ZONISAMIDE 25 mg/1Jul 15, 2026Sep 2, 2026
Skyepharma Production SasZONISAMIDE 100 mg/kgJul 15, 2026Sep 2, 2026
Skyepharma Production SasZONISAMIDE 25 mg/kgJul 15, 2026Sep 2, 2026
Sun Pharmaceutical Industries, Inc.ZONISAMIDE 100 mg/1Jul 15, 2026Sep 2, 2026
Sun Pharmaceutical Industries, Inc.ZONISAMIDE 25 mg/1Jul 15, 2026Sep 2, 2026
Sun Pharmaceutical Industries, Inc.ZONISAMIDE 50 mg/1Jul 15, 2026Sep 2, 2026
Unichem Pharmaceuticals (USA), Inc.ZONISAMIDE 100 mg/1Jul 15, 2026Sep 2, 2026
Unichem Pharmaceuticals (USA), Inc.ZONISAMIDE 50 mg/1Jul 15, 2026Sep 2, 2026
Unichem Pharmaceuticals (USA), Inc.ZONISAMIDE 25 mg/1Jul 15, 2026Sep 2, 2026
Viona Pharmaceuticals IncZONISAMIDE 25 mg/1Jul 15, 2026Sep 2, 2026
Viona Pharmaceuticals IncZONISAMIDE 50 mg/1Jul 15, 2026Sep 2, 2026
Viona Pharmaceuticals IncZONISAMIDE 100 mg/1Jul 15, 2026Sep 2, 2026

Roster from daily NDC Directory diffs — first/last seen dates start July 2026.

Cite this page

DrugDashboards, "Zonegran — NDC 59212-0681-10," retrieved September 3, 2026, https://drugdashboards.com/drug/59212068110.

Free to cite with attribution — see how the data is put together.