DrugDashboards

Itch Relief

Diphenhydramine HCl, Zinc acetate · ZINC ACETATE 1 mg/mL; DIPHENHYDRAMINE HYDROCHLORIDE 20 mg/mL · Spray · Topical · The Kroger Co.

NDC 59450-0295-20 · 59 mL in 1 BOTTLE, SPRAY · OTC MONOGRAPH DRUG · View full market →

The short version

10 companies supply this market — deep enough that no single failure threatens the supply.

The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.

Medicare Part D

Medicare Part D does not cover over-the-counter drugs — by law it pays only for products requiring a prescription.

How Part D pricing works →

NADAC price per unit

No NADAC pricing on file for this NDC — NADAC covers drugs dispensed by retail community pharmacies.

Supply fragility

Not scored — fragility is computed for NADAC-priced NDCs.

90-day shortage risk (model v2)

0.1%chance of a new FDA shortage posting for diphenhydramine hcl, zinc acetate (other) in the next 90 days

price up 13% YoY · sole-source market

For scale: the typical drug’s chance is about 0.1% — this one is in ordinary territory.

Backtested statistical model over the whole market, not this package alone. Model details →

Regulatory

Application
M016
TE code
—
Approval date
—
Patents / exclusivity
None on file

Shortage history

No FDA shortage reports for this drug or its presentations.

Recalls (this NDC)

No enforcement reports list this package NDC.

Manufacturers of Diphenhydramine HCl, Zinc acetate (Spray)

LabelerStrengthFirst seenLast seen
Amerisourcebergen Drug CorporationZINC ACETATE .1 g/100mL; DIPHENHYDRAMINE HYDROCHLORIDE 2 g/100mLAug 26, 2026Sep 2, 2026
Cardinal Health, 110 dba LeaderDIPHENHYDRAMINE HYDROCHLORIDE 20 mg/mL; ZINC ACETATE 1 mg/mLJul 15, 2026Sep 2, 2026
Chain Drug Marketing AssociationZINC ACETATE .1 g/100mL; DIPHENHYDRAMINE HYDROCHLORIDE 2 g/100mLAug 26, 2026Sep 2, 2026
CvsZINC ACETATE .1 g/100mL; DIPHENHYDRAMINE HYDROCHLORIDE 2 g/100mLAug 26, 2026Sep 2, 2026
Geiss, Destin & Dunn, IncDIPHENHYDRAMINE HYDROCHLORIDE 2 g/100mL; ZINC ACETATE .1 g/100mLJul 15, 2026Sep 2, 2026
Meijer, Inc.DIPHENHYDRAMINE HYDROCHLORIDE 20 mg/mL; ZINC ACETATE 1 mg/mLJul 15, 2026Sep 2, 2026
Old East Main Co.DIPHENHYDRAMINE HYDROCHLORIDE 20 mg/mL; ZINC ACETATE 1 mg/mLJul 15, 2026Sep 2, 2026
The Kroger Co.ZINC ACETATE 1 mg/mL; DIPHENHYDRAMINE HYDROCHLORIDE 20 mg/mLAug 26, 2026Sep 2, 2026
Valu MerchandisersZINC ACETATE .1 g/100mL; DIPHENHYDRAMINE HYDROCHLORIDE 2 g/100mLAug 26, 2026Sep 2, 2026
Westlake HB Pharma LLCZINC ACETATE .1 g/100mL; DIPHENHYDRAMINE HYDROCHLORIDE 2 g/100mLAug 26, 2026Sep 2, 2026
Amerisourcebergen Drug CorporationZINC ACETATE 2 g/100mL; DIPHENHYDRAMINE HYDROCHLORIDE .1 g/100mLJul 22, 2026Aug 19, 2026
Chain Drug Marketing AssociationZINC ACETATE 2 g/100mL; DIPHENHYDRAMINE HYDROCHLORIDE .1 g/100mLJul 22, 2026Aug 19, 2026
CvsZINC ACETATE 2 g/100mL; DIPHENHYDRAMINE HYDROCHLORIDE .1 g/100mLJul 22, 2026Aug 19, 2026
The Kroger Co.ZINC ACETATE 20 mg/mL; DIPHENHYDRAMINE HYDROCHLORIDE 1 mg/mLJul 22, 2026Aug 19, 2026
Valu MerchandisersZINC ACETATE 2 g/100mL; DIPHENHYDRAMINE HYDROCHLORIDE .1 g/100mLJul 22, 2026Aug 19, 2026
Westlake HB Pharma LLCZINC ACETATE 2 g/100mL; DIPHENHYDRAMINE HYDROCHLORIDE .1 g/100mLJul 22, 2026Aug 19, 2026
Amerisourcebergen Drug CorporationDIPHENHYDRAMINE HYDROCHLORIDE 2 g/100mL; ZINC ACETATE .1 g/100mLJul 15, 2026Jul 15, 2026
Chain Drug Marketing AssociationDIPHENHYDRAMINE HYDROCHLORIDE 2 g/100mL; ZINC ACETATE .1 g/100mLJul 15, 2026Jul 15, 2026
CvsDIPHENHYDRAMINE HYDROCHLORIDE 2 g/100mL; ZINC ACETATE .1 g/100mLJul 15, 2026Jul 15, 2026
The Kroger Co.DIPHENHYDRAMINE HYDROCHLORIDE 20 mg/mL; ZINC ACETATE 1 mg/mLJul 15, 2026Jul 15, 2026
Valu MerchandisersDIPHENHYDRAMINE HYDROCHLORIDE 2 g/100mL; ZINC ACETATE .1 g/100mLJul 15, 2026Jul 15, 2026
Westlake HB Pharma LLCDIPHENHYDRAMINE HYDROCHLORIDE 2 g/100mL; ZINC ACETATE .1 g/100mLJul 15, 2026Jul 15, 2026

Roster from daily NDC Directory diffs — first/last seen dates start July 2026.

Cite this page

DrugDashboards, "Itch Relief — NDC 59450-0295-20," retrieved September 3, 2026, https://drugdashboards.com/drug/59450029520.

Free to cite with attribution — see how the data is put together.