DrugDashboards

Naloxone Hydrochloride

Naloxone · NALOXONE HYDROCHLORIDE 4 mg/.1mL · Spray · Nasal · Amneal Pharmaceuticals NY LLC

NDC 60219-2104-07 · 2 VIAL in 1 CARTON / .1 mL in 1 VIAL · ANDA · View full market →

The short version

Only one company currently supplies this market — there is no backup if it stumbles. The price has fallen 34% in a year, to $16.92 per unit — and generics that get this cheap tend to get abandoned rather than defended. Put together: worth watching — several of the pressures that precede supply trouble are present at once.

The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.

Medicare Part D

No Medicare Part D plan in CMS's quarterly files lists this product. That usually means it is discontinued, a repackager's listing, or a product no plan has added to its formulary.

How Part D pricing works →

NADAC price per unit

$0$10.00$20.00$30.00Nov 2024Sep 2026$16.92
19 price points · per EASource: CMS NADAC

Estimated fill cost

WAC per package, as filed
$52.00
Reported to Texas DSHS · 2026 annual filing · Amneal Pharmaceuticals LLC

Manufacturer list price as filed — not what pharmacies actually pay after discounts.

Medicaid spend (2025)

$4,902
77 prescriptions paid by Medicaid nationally · all Medicaid spend →

Supply fragility

38Elevated risk

The score is counting real pressure here. One of these alone is routine; it’s the combination that makes this market worth watching.

  • 1 active manufacturer+30
  • price down 27% year over year+8

The score counts pressure that is already visible — fewer makers, shortages, recalls, falling prices. 0 means none of it; 100 means all of it at once. Recomputed daily · as of Sep 3, 2026

90-day shortage risk (model v2)

0.1%chance of a new FDA shortage posting for naloxone (other) in the next 90 days

sole-source market

For scale: the typical drug’s chance is about 0.1% — this one is in ordinary territory.

Backtested statistical model over the whole market, not this package alone. Model details →

Regulatory

Application
ANDA217992
TE code
Approval date
Apr 23, 2024
Patents / exclusivity
None on file

Shortage history

No FDA shortage reports for this drug or its presentations.

Recalls (this NDC)

No enforcement reports list this package NDC.

Manufacturers of Naloxone (Spray)

LabelerStrengthFirst seenLast seen
Amneal Pharmaceuticals NY LLCNALOXONE HYDROCHLORIDE 4 mg/.1mLJul 15, 2026Sep 2, 2026

Roster from daily NDC Directory diffs — first/last seen dates start July 2026.

Cite this page

DrugDashboards, "Naloxone Hydrochloride — NDC 60219-2104-07," retrieved September 3, 2026, https://drugdashboards.com/drug/60219210407.

Free to cite with attribution — see how the data is put together.