The short version
Just 3 companies supply this market — thin enough that a single exit would be felt immediately.
The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.
Pilocarpine Hydrochloride Ophthalmic
Pilocarpine Hydrochloride · PILOCARPINE HYDROCHLORIDE 12.5 mg/mL · Solution/ Drops · Ophthalmic · Amneal Pharmaceuticals NY LLC
NDC 60219-2649-01 · 1 BOTTLE, DROPPER in 1 CARTON / 5 mL in 1 BOTTLE, DROPPER · ANDA · View full market →
Medicare Part D
All Part D pricing →Matched to CMS's representative package for this drug (NDC 60219-2366-02) — same generic, strength, and dosage form. CMS prices one NDC per drug concept, not every package.
ⓘ How this was built
Data sources
- CMS quarterly Prescription Drug Plan Formulary & Pricing files (SPUF)
Method
Negotiated 30-day point-of-sale unit prices and formulary terms aggregated across every unsuppressed Part D and MA-PD plan for the quarter shown. Point of sale means gross of confidential rebates. CMS publishes one representative NDC per drug concept (RxCUI) rather than every package, so these figures come from CMS's representative package for the same drug — matched on generic name, strength, and dosage form. Estimated from MedPAC's program-wide rebate aggregates (June 2023: DIR = 29% of gross Part D spending; brand rebates ≈ 25–40% of gross, generics minimal). Actual rebates are confidential and vary widely by drug — this is a range, not a fact about this drug.
Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.
Plans pay at point of saleⓘ
$18.47per unit
middle half $18.46–$18.57 · 331 plans · Apr 1, 2026
Est. net of rebatesⓘ
≈ $18.47
generic — rebates are minimal, so net ≈ gross
Coverage & restrictions
6%of plans cover it
tier 3 · prior auth 10% · step therapy 0% · qty limit 10%
*No drug-level rebate is public — the estimate applies MedPAC's program-wide brand rebate range to this drug's gross price. Tracked here for 3 quarters since 2024.
NADAC price per unit
No NADAC pricing on file for this NDC — NADAC covers drugs dispensed by retail community pharmacies.
Estimated fill cost
WAC per package, as filed
$106.90
Reported to Texas DSHS · 2026 annual filing · Amneal Pharmaceuticals LLC
Manufacturer list price as filed — not what pharmacies actually pay after discounts.
Supply fragility
Not scored — fragility is computed for NADAC-priced NDCs.
90-day shortage risk (model v2)
0.2%chance of a new FDA shortage posting for pilocarpine hydrochloride (other) in the next 90 days
OAI inspection at a producing facility (24 months) · sole-source market
For scale: the typical drug’s chance is about 0.1% — this one is in ordinary territory.
Backtested statistical model over the whole market, not this package alone. Model details →
Where it's made
- analysis · manufacture · pack · sterilize
Establishments this product's FDA label declares, located via FDA registration data. How we built this →
Regulatory
- Application
- ANDA217733
- TE code
- —
- Approval date
- Apr 28, 2025
- Patents / exclusivity
- None on file
Shortage history
- Planned discontinuation — Vuity, Ophthalmic Solution, 12.5 mg/1 mL (NDC 0074-7098-04)Mar 24, 2026
- Planned discontinuation — Vuity, Ophthalmic Solution, 12.5 mg/1 mL (NDC 0074-7098-06)Mar 24, 2026
Recalls (this NDC)
No enforcement reports list this package NDC.
Manufacturers of Pilocarpine Hydrochloride (Solution/ Drops)
| Labeler | Strength | First seen | Last seen |
|---|---|---|---|
| Amneal Pharmaceuticals NY LLC | PILOCARPINE HYDROCHLORIDE 12.5 mg/mL | Jul 15, 2026 | Sep 3, 2026 |
| AbbVie Inc. | PILOCARPINE HYDROCHLORIDE 12.5 mg/mL | Jul 15, 2026 | Sep 2, 2026 |
| Amneal Pharmaceuticals NY LLC | PILOCARPINE HYDROCHLORIDE 10 mg/mL | Jul 15, 2026 | Sep 2, 2026 |
| Amneal Pharmaceuticals NY LLC | PILOCARPINE HYDROCHLORIDE 20 mg/mL | Jul 15, 2026 | Sep 2, 2026 |
| Amneal Pharmaceuticals NY LLC | PILOCARPINE HYDROCHLORIDE 40 mg/mL | Jul 15, 2026 | Sep 2, 2026 |
| Sandoz Inc | PILOCARPINE HYDROCHLORIDE 20 mg/mL | Jul 15, 2026 | Sep 2, 2026 |
| Sandoz Inc | PILOCARPINE HYDROCHLORIDE 10 mg/mL | Jul 15, 2026 | Sep 2, 2026 |
| Sandoz Inc | PILOCARPINE HYDROCHLORIDE 40 mg/mL | Jul 15, 2026 | Sep 2, 2026 |
Roster from daily NDC Directory diffs — first/last seen dates start July 2026.
Cite this page
DrugDashboards, "Pilocarpine Hydrochloride Ophthalmic — NDC 60219-2649-01," retrieved September 3, 2026, https://drugdashboards.com/drug/60219264901.
Free to cite with attribution — see how the data is put together.