DrugDashboards

Desipramine Hydrochloride

Desipramine Hydrochloride · DESIPRAMINE HYDROCHLORIDE 10 mg/1 · Tablet · Oral · Chartwell RX, LLC

NDC 62135-0593-12 · 120 TABLET in 1 BOTTLE · ANDA · View full market →

The short version

4 companies supply this market — a reasonable cushion if one runs into trouble. The price is up 21% over the past year, to $0.1612 per unit. Put together: this looks like a healthy supply — the boring kind, which is exactly what you want. Historically, drugs in this position went on to a new shortage within 90 days about 0.3% of the time — roughly 2× the typical drug (0.1%).

The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.

One drug, every price

The same NDC has different prices depending on who is paying. Units differ between rungs — compare within a rung over time, not rung against rung, unless the units match.

ⓘ How this was built
Data sources
  • CMS NADAC (pharmacy acquisition, weekly)
  • CMS Part B ASP quarterly payment limits
  • CMS Maximum Fair Prices (IRA negotiated, NDC-level)
  • Medicare Part D Spending by Drug (data.cms.gov, name-matched)
  • VA FSS / Big4 federal contract prices (va.gov, twice monthly)
  • ACA Federal Upper Limits + weighted AMP (data.medicaid.gov, monthly)
  • California SB-17 WAC filings (list price, per package)
Method

Each rung is the newest figure for this NDC from one federal price system, shown with its own unit. Part D is matched by drug name because CMS publishes no NDCs there; it is gross spending, before confidential rebates.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

  • Pharmacies pay (NADAC)$0.1612per EAinvoice-surveyed acquisition cost · May 20, 2026
  • Medicaid generic ceiling (FUL)$0.1596per TABweighted avg manufacturer price $0.0649 · Apr 1, 202699% of what pharmacies pay — a deeper discount than 95% of drugs with this benchmark

Medicare Part D

All Part D pricing →

Matched to CMS's representative package for this drug (NDC 50742-0112-01) — same generic, strength, and dosage form. CMS prices one NDC per drug concept, not every package.

ⓘ How this was built
Data sources
  • CMS quarterly Prescription Drug Plan Formulary & Pricing files (SPUF)
Method

Negotiated 30-day point-of-sale unit prices and formulary terms aggregated across every unsuppressed Part D and MA-PD plan for the quarter shown. Point of sale means gross of confidential rebates. CMS publishes one representative NDC per drug concept (RxCUI) rather than every package, so these figures come from CMS's representative package for the same drug — matched on generic name, strength, and dosage form. Estimated from MedPAC's program-wide rebate aggregates (June 2023: DIR = 29% of gross Part D spending; brand rebates ≈ 25–40% of gross, generics minimal). Actual rebates are confidential and vary widely by drug — this is a range, not a fact about this drug.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

Plans pay at point of sale
$0.3039per unit
middle half $0.1751$0.6375 · 5,496 plans · Apr 1, 2026
Est. net of rebates
≈ $0.3039
generic — rebates are minimal, so net ≈ gross
Coverage & restrictions
100%of plans cover it
tier 4 · prior auth 47% · step therapy 0% · qty limit 0%

*No drug-level rebate is public — the estimate applies MedPAC's program-wide brand rebate range to this drug's gross price. Tracked here for 10 quarters since 2024.

NADAC price per unit

$0$0.2$0.4$0.6Sep 2023Sep 2026$0.1612
32 price points · per EA · held since Invalid Date · dashed = manufacturer avg (WAMP)Source: CMS NADAC

Estimated fill cost

#30 count
$4.84
#90 count
$14.51

Estimates: latest NADAC unit price × quantity. Pharmacy acquisition cost only — excludes dispensing fees, markup, and insurance terms.

Supply fragility

13Low risk

Some pressure is visible, but not much — here’s everything the score found to count.

  • 4 active manufacturers+5
  • Class I/II recall on same molecule/form in past 12 months+8

The score counts pressure that is already visible — fewer makers, shortages, recalls, falling prices. 0 means none of it; 100 means all of it at once. Recomputed daily · as of Sep 3, 2026

90-day shortage risk (model v2)

0.3%chance of a new FDA shortage posting for desipramine hydrochloride (oral solid) in the next 90 days

6 Class I/II recall(s) in 12 months · OAI inspection at a producing facility (24 months) · sole-source market

For scale: the typical drug’s chance is about 0.1% — this one is 2× that.

Backtested statistical model over the whole market, not this package alone. Model details →

Regulatory

Application
ANDA207433
TE code
Approval date
May 5, 2016
Patents / exclusivity
None on file

Shortage history

  • Planned discontinuation Desipramine Hydrochloride, Tablet, 10 mg (NDC 23155-578-01)Aug 12, 2025
  • Planned discontinuation Desipramine Hydrochloride, Tablet, 100 mg (NDC 23155-582-01)Aug 12, 2025
  • Planned discontinuation Desipramine Hydrochloride, Tablet, 25 mg (NDC 23155-579-01)Aug 12, 2025
  • Planned discontinuation Desipramine Hydrochloride, Tablet, 50 mg (NDC 23155-580-01)Aug 12, 2025
  • Planned discontinuation Desipramine Hydrochloride, Tablet, 75 mg (NDC 23155-581-01)Aug 12, 2025

Recalls (this NDC)

No enforcement reports list this package NDC.

Manufacturers of Desipramine Hydrochloride (Tablet)

LabelerStrengthFirst seenLast seen
Chartwell RX, LLCDESIPRAMINE HYDROCHLORIDE 10 mg/1Jul 15, 2026Sep 2, 2026
Chartwell RX, LLCDESIPRAMINE HYDROCHLORIDE 100 mg/1Jul 15, 2026Sep 2, 2026
Chartwell RX, LLCDESIPRAMINE HYDROCHLORIDE 150 mg/1Jul 15, 2026Sep 2, 2026
Chartwell RX, LLCDESIPRAMINE HYDROCHLORIDE 25 mg/1Jul 15, 2026Sep 2, 2026
Chartwell RX, LLCDESIPRAMINE HYDROCHLORIDE 50 mg/1Jul 15, 2026Sep 2, 2026
Chartwell RX, LLCDESIPRAMINE HYDROCHLORIDE 75 mg/1Jul 15, 2026Sep 2, 2026
Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc.DESIPRAMINE HYDROCHLORIDE 100 mg/1Jul 15, 2026Sep 2, 2026
Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc.DESIPRAMINE HYDROCHLORIDE 25 mg/1Jul 15, 2026Sep 2, 2026
Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc.DESIPRAMINE HYDROCHLORIDE 75 mg/1Jul 15, 2026Sep 2, 2026
Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc.DESIPRAMINE HYDROCHLORIDE 10 mg/1Jul 15, 2026Sep 2, 2026
Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc.DESIPRAMINE HYDROCHLORIDE 50 mg/1Jul 15, 2026Sep 2, 2026
Ingenus Pharmaceuticals, LLCDESIPRAMINE HYDROCHLORIDE 50 mg/1Jul 15, 2026Sep 2, 2026
Ingenus Pharmaceuticals, LLCDESIPRAMINE HYDROCHLORIDE 10 mg/1Jul 15, 2026Sep 2, 2026
Ingenus Pharmaceuticals, LLCDESIPRAMINE HYDROCHLORIDE 100 mg/1Jul 15, 2026Sep 2, 2026
Ingenus Pharmaceuticals, LLCDESIPRAMINE HYDROCHLORIDE 25 mg/1Jul 15, 2026Sep 2, 2026
Ingenus Pharmaceuticals, LLCDESIPRAMINE HYDROCHLORIDE 150 mg/1Jul 15, 2026Sep 2, 2026
Ingenus Pharmaceuticals, LLCDESIPRAMINE HYDROCHLORIDE 75 mg/1Jul 15, 2026Sep 2, 2026
Remedyrepack Inc.DESIPRAMINE HYDROCHLORIDE 10 mg/1Jul 15, 2026Sep 2, 2026

Roster from daily NDC Directory diffs — first/last seen dates start July 2026.

Cite this page

DrugDashboards, "Desipramine Hydrochloride — NDC 62135-0593-12," retrieved September 3, 2026, https://drugdashboards.com/drug/62135059312.

Free to cite with attribution — see how the data is put together.