The short version
Only one company currently supplies this market — there is no backup if it stumbles. It is in shortage right now.
The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.
Methotrexate
Methotrexate Sodium · METHOTREXATE SODIUM 1 g/1 · Injection, Powder, Lyophilized, For Solution · Intra-Arterial; Intramuscular; Intrathecal; Intravenous · Fresenius Kabi USA, LLC
NDC 63323-0122-50 · 1 VIAL in 1 CARTON / 1 INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION in 1 VIAL · ANDA · View full market →
One drug, every price
The same NDC has different prices depending on who is paying. Units differ between rungs — compare within a rung over time, not rung against rung, unless the units match.
ⓘ How this was built
Data sources
- CMS NADAC (pharmacy acquisition, weekly)
- CMS Part B ASP quarterly payment limits
- CMS Maximum Fair Prices (IRA negotiated, NDC-level)
- Medicare Part D Spending by Drug (data.cms.gov, name-matched)
- VA FSS / Big4 federal contract prices (va.gov, twice monthly)
- ACA Federal Upper Limits + weighted AMP (data.medicaid.gov, monthly)
- California SB-17 WAC filings (list price, per package)
Method
Each rung is the newest figure for this NDC from one federal price system, shown with its own unit. Part D is matched by drug name because CMS publishes no NDCs there; it is gross spending, before confidential rebates.
Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.
- Medicare Part B pays (ASP+6%)$2.94per billing unit (50 MG)HCPCS J9260 · Jul 1, 2026
- Part D plans paid (avg)$0.6305per dosage unitgross, before rebates — matched by drug name · 2024
- Federal contracts pay (FSS)$62.63per unitFresenius Kabi, LLC · May 15, 2025
Medicare Part D
No Medicare Part D plan in CMS's quarterly files lists this product. That usually means it is discontinued, a repackager's listing, or a product no plan has added to its formulary.
How Part D pricing works →NADAC price per unit
No NADAC pricing on file for this NDC — NADAC covers drugs dispensed by retail community pharmacies.
Estimated fill cost
WAC per package, as filed
$63.60
Reported to Texas DSHS · 2026 annual filing · Fresenius Kabi USA
Manufacturer list price as filed — not what pharmacies actually pay after discounts.
Medicare Part B (ASP)
Payment limit per 50 MG
$2.941
HCPCS J9260 · Jul 1, 2026 quarter · typically ASP + 6%
Medicaid spend (2025)
$13
11 prescriptions paid by Medicaid nationally · all Medicaid spend →
Supply fragility
Not scored — fragility is computed for NADAC-priced NDCs.
90-day shortage risk (model v2)
0.1%chance of a new FDA shortage posting for methotrexate sodium (injectable) in the next 90 days
sterile injectable
For scale: the typical drug’s chance is about 0.1% — this one is in ordinary territory.
Backtested statistical model over the whole market, not this package alone. Model details →
Where it's made
- Fresenius Kabi USA, LLCUnited Statesanalysis · manufacture
Establishments this product's FDA label declares, located via FDA registration data. How we built this →
Is this a "specialty" drug?
There's no legal definition — it meets 1 of 6 public criteria. Why that matters →
- Part D specialty tier
- Costs ≥ $950/fill · avg $24.59 per prescription
- Biologic (BLA)
- Injectable / infused
- Orphan-drug exclusivity
- REMS program
Regulatory
- Application
- ANDA040266
- TE code
- AP
- Approval date
- Feb 26, 1999
- Patents / exclusivity
- None on file
Shortage history
- In shortage now — Methotrexate Preservative Free, Injection, 1 g (NDC 63323-122-50)Mar 13, 2023month 42 — 2× the typical 20-month injectable shortage · model puts 32% odds it resolves within 6 months
Recalls (this NDC)
No enforcement reports list this package NDC.
Manufacturers of Methotrexate Sodium (Injection, Powder, Lyophilized, For Solution)
| Labeler | Strength | First seen | Last seen |
|---|---|---|---|
| Fresenius Kabi USA, LLC | METHOTREXATE SODIUM 1 g/1 | Jul 15, 2026 | Sep 2, 2026 |
Roster from daily NDC Directory diffs — first/last seen dates start July 2026.
Cite this page
DrugDashboards, "Methotrexate — NDC 63323-0122-50," retrieved September 3, 2026, https://drugdashboards.com/drug/63323012250.
Free to cite with attribution — see how the data is put together.