DrugDashboards

Mucinex Nightshift Cold and Flu

Acetaminophen, Dextromethorphan Hydrobromide, and Triprolidine Hydrochloride · ACETAMINOPHEN 650 mg/20mL; DEXTROMETHORPHAN HYDROBROMIDE 20 mg/20mL; TRIPROLIDINE HYDROCHLORIDE 2.5 mg/20mL · Solution · Oral · Reckitt Benckiser LLC

NDC 63824-0503-66 · 180 mL in 1 BOTTLE · OTC MONOGRAPH DRUG · View full market →

The short version

Only one company currently supplies this market — there is no backup if it stumbles. The price is up 11% over the past year, to $0.0567 per unit.

The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.

Medicare Part D

Medicare Part D does not cover over-the-counter drugs — by law it pays only for products requiring a prescription.

How Part D pricing works →

NADAC price per unit

$0$0.02$0.04$0.06Feb 2021Apr 2022$0.0567
3 price points · per · last surveyed Invalid DateSource: CMS NADAC

Supply fragility

Not scored — fragility is computed for NADAC-priced NDCs.

Is this a "specialty" drug?

There's no legal definition — it meets 1 of 6 public criteria. Why that matters →

  • Part D specialty tier
  • Costs ≥ $950/fill
  • Biologic (BLA)
  • Injectable / infused
  • Orphan-drug exclusivity
  • REMS program · Opioid Analgesic REMS Shared System REMS

Regulatory

Application
M012
TE code
—
Approval date
—
Patents / exclusivity
None on file

Shortage history

No FDA shortage reports for this drug or its presentations.

Recalls (this NDC)

  • Class II · TerminatedApr 15, 2015
    Reckitt Benckiser LLC — Labeling: Label Mix-Up; Bottles of Mucinex Fast-Max liquid are correctly labeled on the front of the label, however the back of the bottle where the Drug Facts labeling is, is missing certain Active Ingredients such as acetaminophen, phenylephrine, dextromethorphan, diphenhydramine, and/or guaifenesin. As a result certain safety warnings associated with those ingredients may also be missing.

Manufacturers of Acetaminophen, Dextromethorphan Hydrobromide, and Triprolidine Hydrochloride (Solution)

LabelerStrengthFirst seenLast seen
Reckitt Benckiser LLCACETAMINOPHEN 650 mg/20mL; TRIPROLIDINE HYDROCHLORIDE 2.5 mg/20mL; DEXTROMETHORPHAN HYDROBROMIDE 20 mg/20mLAug 26, 2026Sep 2, 2026
Reckitt Benckiser LLCACETAMINOPHEN 650 mg/20mL; DEXTROMETHORPHAN HYDROBROMIDE 20 mg/20mL; TRIPROLIDINE HYDROCHLORIDE 2.5 mg/20mLJul 15, 2026Aug 30, 2026
Reckitt Benckiser LLCACETAMINOPHEN 650 mg/20mL; TRIPROLIDINE HYDROCHLORIDE 20 mg/20mL; DEXTROMETHORPHAN HYDROBROMIDE 2.5 mg/20mLJul 22, 2026Aug 19, 2026

Roster from daily NDC Directory diffs — first/last seen dates start July 2026.

Cite this page

DrugDashboards, "Mucinex Nightshift Cold and Flu — NDC 63824-0503-66," retrieved September 3, 2026, https://drugdashboards.com/drug/63824050366.

Free to cite with attribution — see how the data is put together.