Acetaminophen and Diphenhydramine Hydrochloride · ACETAMINOPHEN 500 mg/1; DIPHENHYDRAMINE HYDROCHLORIDE 25 mg/1 · Tablet, Coated · Oral · Chain Drug Marketing Association
NDC 63868-0325-01 · 100 TABLET, COATED in 1 BOTTLE, PLASTIC · OTC MONOGRAPH DRUG · View full market →
20 companies supply this market — deep enough that no single failure threatens the supply. The price is up 10% over the past year, to $0.0504 per unit.
The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.
Medicare Part D does not cover over-the-counter drugs — by law it pays only for products requiring a prescription.
How Part D pricing works →Not scored — fragility is computed for NADAC-priced NDCs.
sole-source market
For scale: the typical drug’s chance is about 0.1% — this one is in ordinary territory.
Backtested statistical model over the whole market, not this package alone. Model details →
There's no legal definition — it meets 1 of 6 public criteria. Why that matters →
No FDA shortage reports for this drug or its presentations.
No enforcement reports list this package NDC.
| Labeler | Strength | First seen | Last seen |
|---|---|---|---|
| Patheon Softgels Inc. | ACETAMINOPHEN 500 mg/1; DIPHENHYDRAMINE HYDROCHLORIDE 25 mg/1 | Jul 15, 2026 | Sep 3, 2026 |
| AAA Pharmaceutical, Inc. | ACETAMINOPHEN 500 mg/1; DIPHENHYDRAMINE HYDROCHLORIDE 25 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Amerifoods Trading Company | ACETAMINOPHEN 500 mg/1; DIPHENHYDRAMINE HYDROCHLORIDE 25 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Chain Drug Marketing Association | ACETAMINOPHEN 500 mg/1; DIPHENHYDRAMINE HYDROCHLORIDE 25 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Chain Drug Marketing Association, Inc. | ACETAMINOPHEN 500 mg/1; DIPHENHYDRAMINE HYDROCHLORIDE 25 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Fsa Store Inc. | ACETAMINOPHEN 500 mg/1; DIPHENHYDRAMINE HYDROCHLORIDE 25 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| GoodSense | ACETAMINOPHEN 500 mg/1; DIPHENHYDRAMINE HYDROCHLORIDE 25 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Grocery Outlet, Inc. | ACETAMINOPHEN 500 mg/1; DIPHENHYDRAMINE HYDROCHLORIDE 25 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Harris Teeter | ACETAMINOPHEN 500 mg/1; DIPHENHYDRAMINE HYDROCHLORIDE 25 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Harris Teeter | ACETAMINOPHEN 500 mg/1; DIPHENHYDRAMINE HYDROCHLORIDE 25 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Heb | ACETAMINOPHEN 500 mg/1; DIPHENHYDRAMINE HYDROCHLORIDE 25 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Hyvee Inc | ACETAMINOPHEN 500 mg/1; DIPHENHYDRAMINE HYDROCHLORIDE 25 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Meijer | ACETAMINOPHEN 500 mg/1; DIPHENHYDRAMINE HYDROCHLORIDE 25 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Retail Business Services , Llc. | ACETAMINOPHEN 500 mg/1; DIPHENHYDRAMINE HYDROCHLORIDE 25 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Safeway | ACETAMINOPHEN 500 mg/1; DIPHENHYDRAMINE HYDROCHLORIDE 25 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| TopCo Associates LLC | ACETAMINOPHEN 500 mg/1; DIPHENHYDRAMINE HYDROCHLORIDE 25 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| United Natural Foods, Inc. dba UNFI | ACETAMINOPHEN 500 mg/1; DIPHENHYDRAMINE HYDROCHLORIDE 25 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Valu Merchandisers Company | ACETAMINOPHEN 500 mg/1; DIPHENHYDRAMINE HYDROCHLORIDE 25 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| WinCo Foods, LLC | ACETAMINOPHEN 500 mg/1; DIPHENHYDRAMINE HYDROCHLORIDE 25 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Marc Glassman, Inc. | ACETAMINOPHEN 500 mg/1; DIPHENHYDRAMINE HYDROCHLORIDE 25 mg/1 | Jul 15, 2026 | Aug 28, 2026 |
Roster from daily NDC Directory diffs — first/last seen dates start July 2026.
DrugDashboards, "Pain Relief PM Extra Strength — NDC 63868-0325-01," retrieved September 3, 2026, https://drugdashboards.com/drug/63868032501.
Free to cite with attribution — see how the data is put together.