DrugDashboards

Losartan Potassium and Hydrochlorothiazide

Losartan Potassium and Hydrochlorothiazide · LOSARTAN POTASSIUM 50 mg/1; HYDROCHLOROTHIAZIDE 12.5 mg/1 · Tablet, Film Coated · Oral · Aurobindo Pharma Limited

NDC 65862-0468-10 · 10 BLISTER PACK in 1 CARTON / 10 TABLET, FILM COATED in 1 BLISTER PACK · ANDA · View full market →

The short version

17 companies supply this market — deep enough that no single failure threatens the supply.

The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.

Medicare Part D

All Part D pricing →

Matched to CMS's representative package for this drug (NDC 78206-0139-01) — same generic, strength, and dosage form. CMS prices one NDC per drug concept, not every package.

ⓘ How this was built
Data sources
  • CMS quarterly Prescription Drug Plan Formulary & Pricing files (SPUF)
Method

Negotiated 30-day point-of-sale unit prices and formulary terms aggregated across every unsuppressed Part D and MA-PD plan for the quarter shown. Point of sale means gross of confidential rebates. CMS publishes one representative NDC per drug concept (RxCUI) rather than every package, so these figures come from CMS's representative package for the same drug — matched on generic name, strength, and dosage form. Estimated from MedPAC's program-wide rebate aggregates (June 2023: DIR = 29% of gross Part D spending; brand rebates ≈ 25–40% of gross, generics minimal). Actual rebates are confidential and vary widely by drug — this is a range, not a fact about this drug.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

Plans pay at point of sale
$5.08per unit
middle half $5.08$5.08 · 2 plans · Apr 1, 2026
Est. net of rebates
≈ $5.08
generic — rebates are minimal, so net ≈ gross
Coverage & restrictions
0%of plans cover it
tier 1 · prior auth 0% · step therapy 0% · qty limit 100%

*No drug-level rebate is public — the estimate applies MedPAC's program-wide brand rebate range to this drug's gross price. Tracked here for 10 quarters since 2024.

NADAC price per unit

No NADAC pricing on file for this NDC — NADAC covers drugs dispensed by retail community pharmacies.

Supply fragility

Not scored — fragility is computed for NADAC-priced NDCs.

90-day shortage risk (model v2)

0.1%chance of a new FDA shortage posting for losartan potassium and hydrochlorothiazide (oral solid) in the next 90 days

OAI inspection at a producing facility (24 months) · sole-source market

For scale: the typical drug’s chance is about 0.1% — this one is in ordinary territory.

Backtested statistical model over the whole market, not this package alone. Model details →

Where it's made

Establishments this product's FDA label declares, located via FDA registration data. How we built this →

Regulatory

Application
ANDA091629
TE code
AB
Approval date
Jan 6, 2010
Patents / exclusivity
None on file

Shortage history

No FDA shortage reports for this drug or its presentations.

Recalls (this NDC)

No enforcement reports list this package NDC.

Manufacturers of Losartan Potassium and Hydrochlorothiazide (Tablet, Film Coated)

LabelerStrengthFirst seenLast seen
A-S Medication SolutionsLOSARTAN POTASSIUM 100 mg/1; HYDROCHLOROTHIAZIDE 25 mg/1Aug 26, 2026Sep 3, 2026
Aurobindo Pharma LimitedLOSARTAN POTASSIUM 100 mg/1; HYDROCHLOROTHIAZIDE 25 mg/1Aug 20, 2026Sep 3, 2026
Aurobindo Pharma LimitedLOSARTAN POTASSIUM 100 mg/1; HYDROCHLOROTHIAZIDE 12.5 mg/1Aug 20, 2026Sep 3, 2026
Bryant Ranch PrepackLOSARTAN POTASSIUM 100 mg/1; HYDROCHLOROTHIAZIDE 25 mg/1Aug 26, 2026Sep 3, 2026
Bryant Ranch PrepackHYDROCHLOROTHIAZIDE 12.5 mg/1; LOSARTAN POTASSIUM 100 mg/1Jul 15, 2026Sep 3, 2026
Bryant Ranch PrepackLOSARTAN POTASSIUM 50 mg/1; HYDROCHLOROTHIAZIDE 12.5 mg/1Aug 26, 2026Sep 3, 2026
DirectRxHYDROCHLOROTHIAZIDE 25 mg/1; LOSARTAN POTASSIUM 100 mg/1Jul 15, 2026Sep 3, 2026
Organon Pharma (Uk) LimitedLOSARTAN POTASSIUM 50 mg/1; HYDROCHLOROTHIAZIDE 12.5 mg/1Aug 20, 2026Sep 3, 2026
Organon Pharma (Uk) LimitedLOSARTAN POTASSIUM 100 mg/1; HYDROCHLOROTHIAZIDE 12.5 mg/1Aug 20, 2026Sep 3, 2026
Organon Pharma (Uk) LimitedLOSARTAN POTASSIUM 100 mg/1; HYDROCHLOROTHIAZIDE 25 mg/1Aug 20, 2026Sep 3, 2026
PD-Rx Pharmaceuticals, Inc.LOSARTAN POTASSIUM 50 mg/1; HYDROCHLOROTHIAZIDE 12.5 mg/1Aug 26, 2026Sep 3, 2026
Proficient Rx LPLOSARTAN POTASSIUM 100 mg/1; HYDROCHLOROTHIAZIDE 12.5 mg/1Aug 26, 2026Sep 3, 2026
Proficient Rx LPLOSARTAN POTASSIUM 50 mg/1; HYDROCHLOROTHIAZIDE 12.5 mg/1Aug 26, 2026Sep 3, 2026
Remedyrepack Inc.LOSARTAN POTASSIUM 100 mg/1; HYDROCHLOROTHIAZIDE 25 mg/1Aug 26, 2026Sep 3, 2026
Alembic Pharmaceuticals Inc.LOSARTAN POTASSIUM 100 mg/1; HYDROCHLOROTHIAZIDE 25 mg/1Aug 26, 2026Sep 2, 2026
Alembic Pharmaceuticals Inc.LOSARTAN POTASSIUM 100 mg/1; HYDROCHLOROTHIAZIDE 12.5 mg/1Aug 26, 2026Sep 2, 2026
Alembic Pharmaceuticals Inc.LOSARTAN POTASSIUM 50 mg/1; HYDROCHLOROTHIAZIDE 12.5 mg/1Aug 26, 2026Sep 2, 2026
Alembic Pharmaceuticals LimitedLOSARTAN POTASSIUM 100 mg/1; HYDROCHLOROTHIAZIDE 25 mg/1Aug 26, 2026Sep 2, 2026
Alembic Pharmaceuticals LimitedLOSARTAN POTASSIUM 100 mg/1; HYDROCHLOROTHIAZIDE 12.5 mg/1Aug 26, 2026Sep 2, 2026
Alembic Pharmaceuticals LimitedLOSARTAN POTASSIUM 50 mg/1; HYDROCHLOROTHIAZIDE 12.5 mg/1Aug 26, 2026Sep 2, 2026
Aphena Pharma Solutions - Tennessee, LLCHYDROCHLOROTHIAZIDE 25 mg/1; LOSARTAN POTASSIUM 100 mg/1Jul 15, 2026Sep 2, 2026
AvKARELOSARTAN POTASSIUM 100 mg/1; HYDROCHLOROTHIAZIDE 12.5 mg/1Aug 26, 2026Sep 2, 2026
AvKARELOSARTAN POTASSIUM 100 mg/1; HYDROCHLOROTHIAZIDE 25 mg/1Aug 26, 2026Sep 2, 2026
AvKARELOSARTAN POTASSIUM 50 mg/1; HYDROCHLOROTHIAZIDE 12.5 mg/1Aug 26, 2026Sep 2, 2026
Bryant Ranch PrepackHYDROCHLOROTHIAZIDE 12.5 mg/1; LOSARTAN POTASSIUM 50 mg/1Jul 15, 2026Sep 2, 2026
Camber Pharmaceuticals, Inc.LOSARTAN POTASSIUM 100 mg/1; HYDROCHLOROTHIAZIDE 25 mg/1Aug 26, 2026Sep 2, 2026
Camber Pharmaceuticals, Inc.LOSARTAN POTASSIUM 50 mg/1; HYDROCHLOROTHIAZIDE 12.5 mg/1Aug 26, 2026Sep 2, 2026
Camber Pharmaceuticals, Inc.LOSARTAN POTASSIUM 100 mg/1; HYDROCHLOROTHIAZIDE 12.5 mg/1Aug 26, 2026Sep 2, 2026
Coupler LLCLOSARTAN POTASSIUM 50 mg/1; HYDROCHLOROTHIAZIDE 12.5 mg/1Aug 26, 2026Sep 2, 2026
Direct RxLOSARTAN POTASSIUM 50 mg/1; HYDROCHLOROTHIAZIDE 12.5 mg/1Aug 26, 2026Sep 2, 2026
Direct RxLOSARTAN POTASSIUM 100 mg/1; HYDROCHLOROTHIAZIDE 25 mg/1Aug 26, 2026Sep 2, 2026
Direct RxLOSARTAN POTASSIUM 100 mg/1; HYDROCHLOROTHIAZIDE 12.5 mg/1Aug 26, 2026Sep 2, 2026
Direct_RxHYDROCHLOROTHIAZIDE 25 mg/1; LOSARTAN POTASSIUM 100 mg/1Jul 15, 2026Sep 2, 2026
Direct_RxLOSARTAN POTASSIUM 100 mg/1; HYDROCHLOROTHIAZIDE 12.5 mg/1Aug 26, 2026Sep 2, 2026
Direct_RxLOSARTAN POTASSIUM 50 mg/1; HYDROCHLOROTHIAZIDE 12.5 mg/1Aug 26, 2026Sep 2, 2026
DirectRxLOSARTAN POTASSIUM 100 mg/1; HYDROCHLOROTHIAZIDE 12.5 mg/1Aug 26, 2026Sep 2, 2026
DirectRxHYDROCHLOROTHIAZIDE 12.5 mg/1; LOSARTAN POTASSIUM 50 mg/1Jul 15, 2026Sep 2, 2026
Granules Pharmaceuticals Inc.LOSARTAN POTASSIUM 100 mg/1; HYDROCHLOROTHIAZIDE 12.5 mg/1Aug 26, 2026Sep 2, 2026
Granules Pharmaceuticals Inc.LOSARTAN POTASSIUM 100 mg/1; HYDROCHLOROTHIAZIDE 25 mg/1Aug 26, 2026Sep 2, 2026
Granules Pharmaceuticals Inc.LOSARTAN POTASSIUM 50 mg/1; HYDROCHLOROTHIAZIDE 12.5 mg/1Aug 26, 2026Sep 2, 2026

Roster from daily NDC Directory diffs — first/last seen dates start July 2026.

Cite this page

DrugDashboards, "Losartan Potassium and Hydrochlorothiazide — NDC 65862-0468-10," retrieved September 3, 2026, https://drugdashboards.com/drug/65862046810.

Free to cite with attribution — see how the data is put together.