The short version
17 companies supply this market — deep enough that no single failure threatens the supply.
The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.
Losartan Potassium And Hydrochlorothiazide
Losartan Potassium And Hydrochlorothiazide · LOSARTAN POTASSIUM 100 mg/1; HYDROCHLOROTHIAZIDE 12.5 mg/1 · Tablet, Film Coated · Oral · Direct_Rx
NDC 72189-0098-90 · 90 TABLET, FILM COATED in 1 BOTTLE · ANDA · View full market →
Medicare Part D
All Part D pricing →Matched to CMS's representative package for this drug (NDC 78206-0140-01) — same generic, strength, and dosage form. CMS prices one NDC per drug concept, not every package.
ⓘ How this was built
Data sources
- CMS quarterly Prescription Drug Plan Formulary & Pricing files (SPUF)
Method
Negotiated 30-day point-of-sale unit prices and formulary terms aggregated across every unsuppressed Part D and MA-PD plan for the quarter shown. Point of sale means gross of confidential rebates. CMS publishes one representative NDC per drug concept (RxCUI) rather than every package, so these figures come from CMS's representative package for the same drug — matched on generic name, strength, and dosage form. Estimated from MedPAC's program-wide rebate aggregates (June 2023: DIR = 29% of gross Part D spending; brand rebates ≈ 25–40% of gross, generics minimal). Actual rebates are confidential and vary widely by drug — this is a range, not a fact about this drug.
Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.
Plans pay at point of saleⓘ
$6.94per unit
middle half $6.94–$6.94 · 2 plans · Apr 1, 2026
Est. net of rebatesⓘ
≈ $6.94
generic — rebates are minimal, so net ≈ gross
Coverage & restrictions
0%of plans cover it
tier 1 · prior auth 0% · step therapy 0% · qty limit 100%
*No drug-level rebate is public — the estimate applies MedPAC's program-wide brand rebate range to this drug's gross price. Tracked here for 10 quarters since 2024.
NADAC price per unit
No NADAC pricing on file for this NDC — NADAC covers drugs dispensed by retail community pharmacies.
Supply fragility
Not scored — fragility is computed for NADAC-priced NDCs.
90-day shortage risk (model v2)
0.1%chance of a new FDA shortage posting for losartan potassium and hydrochlorothiazide (oral solid) in the next 90 days
OAI inspection at a producing facility (24 months) · sole-source market
For scale: the typical drug’s chance is about 0.1% — this one is in ordinary territory.
Backtested statistical model over the whole market, not this package alone. Model details →
Where it's made
- Direct RxUnited Statesrepack
Establishments this product's FDA label declares, located via FDA registration data. How we built this →
Regulatory
- Application
- ANDA077157
- TE code
- AB
- Approval date
- Apr 6, 2010
- Patents / exclusivity
- None on file
Shortage history
No FDA shortage reports for this drug or its presentations.
Recalls (this NDC)
- Class II · TerminatedMay 5, 2022Direct Rx — CGMP Deviations- AZIDO Impurity levels observed to be above acceptable limits
Manufacturers of Losartan Potassium And Hydrochlorothiazide (Tablet, Film Coated)
| Labeler | Strength | First seen | Last seen |
|---|---|---|---|
| A-S Medication Solutions | LOSARTAN POTASSIUM 100 mg/1; HYDROCHLOROTHIAZIDE 25 mg/1 | Aug 26, 2026 | Sep 3, 2026 |
| Aurobindo Pharma Limited | LOSARTAN POTASSIUM 100 mg/1; HYDROCHLOROTHIAZIDE 25 mg/1 | Aug 20, 2026 | Sep 3, 2026 |
| Aurobindo Pharma Limited | LOSARTAN POTASSIUM 100 mg/1; HYDROCHLOROTHIAZIDE 12.5 mg/1 | Aug 20, 2026 | Sep 3, 2026 |
| Bryant Ranch Prepack | LOSARTAN POTASSIUM 100 mg/1; HYDROCHLOROTHIAZIDE 25 mg/1 | Aug 26, 2026 | Sep 3, 2026 |
| Bryant Ranch Prepack | HYDROCHLOROTHIAZIDE 12.5 mg/1; LOSARTAN POTASSIUM 100 mg/1 | Jul 15, 2026 | Sep 3, 2026 |
| Bryant Ranch Prepack | LOSARTAN POTASSIUM 50 mg/1; HYDROCHLOROTHIAZIDE 12.5 mg/1 | Aug 26, 2026 | Sep 3, 2026 |
| DirectRx | HYDROCHLOROTHIAZIDE 25 mg/1; LOSARTAN POTASSIUM 100 mg/1 | Jul 15, 2026 | Sep 3, 2026 |
| Organon Pharma (Uk) Limited | LOSARTAN POTASSIUM 50 mg/1; HYDROCHLOROTHIAZIDE 12.5 mg/1 | Aug 20, 2026 | Sep 3, 2026 |
| Organon Pharma (Uk) Limited | LOSARTAN POTASSIUM 100 mg/1; HYDROCHLOROTHIAZIDE 12.5 mg/1 | Aug 20, 2026 | Sep 3, 2026 |
| Organon Pharma (Uk) Limited | LOSARTAN POTASSIUM 100 mg/1; HYDROCHLOROTHIAZIDE 25 mg/1 | Aug 20, 2026 | Sep 3, 2026 |
| PD-Rx Pharmaceuticals, Inc. | LOSARTAN POTASSIUM 50 mg/1; HYDROCHLOROTHIAZIDE 12.5 mg/1 | Aug 26, 2026 | Sep 3, 2026 |
| Proficient Rx LP | LOSARTAN POTASSIUM 100 mg/1; HYDROCHLOROTHIAZIDE 12.5 mg/1 | Aug 26, 2026 | Sep 3, 2026 |
| Proficient Rx LP | LOSARTAN POTASSIUM 50 mg/1; HYDROCHLOROTHIAZIDE 12.5 mg/1 | Aug 26, 2026 | Sep 3, 2026 |
| Remedyrepack Inc. | LOSARTAN POTASSIUM 100 mg/1; HYDROCHLOROTHIAZIDE 25 mg/1 | Aug 26, 2026 | Sep 3, 2026 |
| Alembic Pharmaceuticals Inc. | LOSARTAN POTASSIUM 100 mg/1; HYDROCHLOROTHIAZIDE 25 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| Alembic Pharmaceuticals Inc. | LOSARTAN POTASSIUM 100 mg/1; HYDROCHLOROTHIAZIDE 12.5 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| Alembic Pharmaceuticals Inc. | LOSARTAN POTASSIUM 50 mg/1; HYDROCHLOROTHIAZIDE 12.5 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| Alembic Pharmaceuticals Limited | LOSARTAN POTASSIUM 100 mg/1; HYDROCHLOROTHIAZIDE 25 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| Alembic Pharmaceuticals Limited | LOSARTAN POTASSIUM 100 mg/1; HYDROCHLOROTHIAZIDE 12.5 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| Alembic Pharmaceuticals Limited | LOSARTAN POTASSIUM 50 mg/1; HYDROCHLOROTHIAZIDE 12.5 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| Aphena Pharma Solutions - Tennessee, LLC | HYDROCHLOROTHIAZIDE 25 mg/1; LOSARTAN POTASSIUM 100 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| AvKARE | LOSARTAN POTASSIUM 100 mg/1; HYDROCHLOROTHIAZIDE 12.5 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| AvKARE | LOSARTAN POTASSIUM 100 mg/1; HYDROCHLOROTHIAZIDE 25 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| AvKARE | LOSARTAN POTASSIUM 50 mg/1; HYDROCHLOROTHIAZIDE 12.5 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| Bryant Ranch Prepack | HYDROCHLOROTHIAZIDE 12.5 mg/1; LOSARTAN POTASSIUM 50 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Camber Pharmaceuticals, Inc. | LOSARTAN POTASSIUM 100 mg/1; HYDROCHLOROTHIAZIDE 25 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| Camber Pharmaceuticals, Inc. | LOSARTAN POTASSIUM 50 mg/1; HYDROCHLOROTHIAZIDE 12.5 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| Camber Pharmaceuticals, Inc. | LOSARTAN POTASSIUM 100 mg/1; HYDROCHLOROTHIAZIDE 12.5 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| Coupler LLC | LOSARTAN POTASSIUM 50 mg/1; HYDROCHLOROTHIAZIDE 12.5 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| Direct Rx | LOSARTAN POTASSIUM 50 mg/1; HYDROCHLOROTHIAZIDE 12.5 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| Direct Rx | LOSARTAN POTASSIUM 100 mg/1; HYDROCHLOROTHIAZIDE 25 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| Direct Rx | LOSARTAN POTASSIUM 100 mg/1; HYDROCHLOROTHIAZIDE 12.5 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| Direct_Rx | HYDROCHLOROTHIAZIDE 25 mg/1; LOSARTAN POTASSIUM 100 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Direct_Rx | LOSARTAN POTASSIUM 100 mg/1; HYDROCHLOROTHIAZIDE 12.5 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| Direct_Rx | LOSARTAN POTASSIUM 50 mg/1; HYDROCHLOROTHIAZIDE 12.5 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| DirectRx | LOSARTAN POTASSIUM 100 mg/1; HYDROCHLOROTHIAZIDE 12.5 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| DirectRx | HYDROCHLOROTHIAZIDE 12.5 mg/1; LOSARTAN POTASSIUM 50 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Granules Pharmaceuticals Inc. | LOSARTAN POTASSIUM 100 mg/1; HYDROCHLOROTHIAZIDE 12.5 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| Granules Pharmaceuticals Inc. | LOSARTAN POTASSIUM 100 mg/1; HYDROCHLOROTHIAZIDE 25 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| Granules Pharmaceuticals Inc. | LOSARTAN POTASSIUM 50 mg/1; HYDROCHLOROTHIAZIDE 12.5 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
Roster from daily NDC Directory diffs — first/last seen dates start July 2026.
Cite this page
DrugDashboards, "Losartan Potassium And Hydrochlorothiazide — NDC 72189-0098-90," retrieved September 3, 2026, https://drugdashboards.com/drug/72189009890.
Free to cite with attribution — see how the data is put together.