The short version
8 companies supply this market — a reasonable cushion if one runs into trouble.
The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.
Methadone Hydrochloride
Methadone Hydrochloride · METHADONE HYDROCHLORIDE 10 mg/mL · Concentrate · Oral · VistaPharm, LLC
NDC 66689-0694-79 · 1000 mL in 1 BOTTLE · ANDA · View full market →
One drug, every price
The same NDC has different prices depending on who is paying. Units differ between rungs — compare within a rung over time, not rung against rung, unless the units match.
ⓘ How this was built
Data sources
- CMS NADAC (pharmacy acquisition, weekly)
- CMS Part B ASP quarterly payment limits
- CMS Maximum Fair Prices (IRA negotiated, NDC-level)
- Medicare Part D Spending by Drug (data.cms.gov, name-matched)
- VA FSS / Big4 federal contract prices (va.gov, twice monthly)
- ACA Federal Upper Limits + weighted AMP (data.medicaid.gov, monthly)
- California SB-17 WAC filings (list price, per package)
Method
Each rung is the newest figure for this NDC from one federal price system, shown with its own unit. Part D is matched by drug name because CMS publishes no NDCs there; it is gross spending, before confidential rebates.
Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.
- Federal contracts pay (FSS)$77.01per package of 1000MLGolden State Medical Supply, Inc. · Jun 15, 2024
- Medicaid generic ceiling (FUL)$0.5540per MLweighted avg manufacturer price $0.0288 · Aug 1, 2026
Medicare Part D
No Medicare Part D plan in CMS's quarterly files lists this product. That usually means it is discontinued, a repackager's listing, or a product no plan has added to its formulary.
How Part D pricing works →NADAC price per unit
Estimated fill cost
WAC per package, as filed
$86.00
Reported to Texas DSHS · 2026 annual filing · PAI Holdings LLC dba Pharmaceutical Associates, Inc. / PAI Pharma
Manufacturer list price as filed — not what pharmacies actually pay after discounts.
Medicaid spend (2025)
$9.7M
1,355,177 prescriptions paid by Medicaid nationally · all Medicaid spend →
Supply fragility
Not scored — fragility is computed for NADAC-priced NDCs.
90-day shortage risk (model v2)
0.1%chance of a new FDA shortage posting for methadone hydrochloride (other) in the next 90 days
sole-source market · price up 3% YoY
For scale: the typical drug’s chance is about 0.1% — this one is in ordinary territory.
Backtested statistical model over the whole market, not this package alone. Model details →
Is this a "specialty" drug?
There's no legal definition — it meets 1 of 6 public criteria. Why that matters →
- Part D specialty tier
- Costs ≥ $950/fill
- Biologic (BLA)
- Injectable / infused
- Orphan-drug exclusivity
- REMS program · Opioid Analgesic REMS Shared System REMS
Regulatory
- Application
- ANDA040088
- TE code
- AA
- Approval date
- Nov 30, 1994
- Patents / exclusivity
- None on file
Shortage history
No FDA shortage reports for this drug or its presentations.
Recalls (this NDC)
- Class II · TerminatedJan 18, 2017VistaPharm, Inc. — CGMP Deviations: Purified water used to manufacture the drug products may have been contaminated with Burkholderia cepacia.
- Class II · TerminatedJan 18, 2017VistaPharm, Inc. — CGMP Deviations: Purified water used to manufacture the drug products may have been contaminated with Burkholderia cepacia.
Manufacturers of Methadone Hydrochloride (Concentrate)
| Labeler | Strength | First seen | Last seen |
|---|---|---|---|
| Bryant Ranch Prepack | METHADONE HYDROCHLORIDE 10 mg/mL | Jul 15, 2026 | Sep 3, 2026 |
| VistaPharm, LLC | METHADONE HYDROCHLORIDE 10 mg/mL | Jul 15, 2026 | Sep 3, 2026 |
| Atlantic Biologicals Corp. | METHADONE HYDROCHLORIDE 10 mg/mL | Jul 15, 2026 | Sep 2, 2026 |
| Atlantic Biologicals Corp. | METHADONE HYDROCHLORIDE 10 mg/mL | Jul 15, 2026 | Sep 2, 2026 |
| Hikma Pharmaceuticals USA Inc. | METHADONE HYDROCHLORIDE 10 mg/mL | Jul 15, 2026 | Sep 2, 2026 |
| Lannett Company, Inc. | METHADONE HYDROCHLORIDE 10 mg/mL | Jul 15, 2026 | Sep 2, 2026 |
| Hikma Pharmaceuticals USA | METHADONE HYDROCHLORIDE 10 mg/mL | Jul 15, 2026 | Aug 31, 2026 |
| SpecGx LLC | METHADONE HYDROCHLORIDE 10 mg/mL | Jul 15, 2026 | Aug 31, 2026 |
Roster from daily NDC Directory diffs — first/last seen dates start July 2026.
Cite this page
DrugDashboards, "Methadone Hydrochloride — NDC 66689-0694-79," retrieved September 3, 2026, https://drugdashboards.com/drug/66689069479.
Free to cite with attribution — see how the data is put together.