The short version
18 companies supply this market — deep enough that no single failure threatens the supply.
The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.
topiramate · TOPIRAMATE 100 mg/1 · Tablet, Film Coated · Oral · Coupler LLC
NDC 67046-0357-03 · 30 TABLET, FILM COATED in 1 BLISTER PACK · ANDA · View full market →
18 companies supply this market — deep enough that no single failure threatens the supply.
The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.
Matched to CMS's representative package for this drug (NDC 68382-0140-05) — same generic, strength, and dosage form. CMS prices one NDC per drug concept, not every package.
Negotiated 30-day point-of-sale unit prices and formulary terms aggregated across every unsuppressed Part D and MA-PD plan for the quarter shown. Point of sale means gross of confidential rebates. CMS publishes one representative NDC per drug concept (RxCUI) rather than every package, so these figures come from CMS's representative package for the same drug — matched on generic name, strength, and dosage form. Estimated from MedPAC's program-wide rebate aggregates (June 2023: DIR = 29% of gross Part D spending; brand rebates ≈ 25–40% of gross, generics minimal). Actual rebates are confidential and vary widely by drug — this is a range, not a fact about this drug.
Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.
*No drug-level rebate is public — the estimate applies MedPAC's program-wide brand rebate range to this drug's gross price. Tracked here for 10 quarters since 2024.
No NADAC pricing on file for this NDC — NADAC covers drugs dispensed by retail community pharmacies.
Not scored — fragility is computed for NADAC-priced NDCs.
OAI inspection at a producing facility (24 months) · sole-source market
For scale: the typical drug’s chance is about 0.1% — this one is in ordinary territory.
Backtested statistical model over the whole market, not this package alone. Model details →
No FDA shortage reports for this drug or its presentations.
No enforcement reports list this package NDC.
| Labeler | Strength | First seen | Last seen |
|---|---|---|---|
| A-S Medication Solutions | TOPIRAMATE 50 mg/1 | Jul 15, 2026 | Sep 3, 2026 |
| Aurobindo Pharma Limited | TOPIRAMATE 50 mg/1 | Jul 15, 2026 | Sep 3, 2026 |
| Aurobindo Pharma Limited | TOPIRAMATE 200 mg/1 | Jul 15, 2026 | Sep 3, 2026 |
| Bryant Ranch Prepack | TOPIRAMATE 25 mg/1 | Jul 15, 2026 | Sep 3, 2026 |
| Bryant Ranch Prepack | TOPIRAMATE 100 mg/1 | Jul 15, 2026 | Sep 3, 2026 |
| Bryant Ranch Prepack | TOPIRAMATE 50 mg/1 | Jul 15, 2026 | Sep 3, 2026 |
| Bryant Ranch Prepack | TOPIRAMATE 200 mg/1 | Jul 15, 2026 | Sep 3, 2026 |
| Coupler LLC | TOPIRAMATE 25 mg/1 | Jul 15, 2026 | Sep 3, 2026 |
| NuCare Pharmaceuticals,Inc. | TOPIRAMATE 50 mg/1 | Jul 15, 2026 | Sep 3, 2026 |
| PD-Rx Pharmaceuticals, Inc. | TOPIRAMATE 50 mg/1 | Jul 15, 2026 | Sep 3, 2026 |
| PD-Rx Pharmaceuticals, Inc. | TOPIRAMATE 25 mg/1 | Jul 15, 2026 | Sep 3, 2026 |
| Proficient Rx LP | TOPIRAMATE 50 mg/1 | Jul 15, 2026 | Sep 3, 2026 |
| Proficient Rx LP | TOPIRAMATE 100 mg/1 | Jul 15, 2026 | Sep 3, 2026 |
| Remedyrepack Inc. | TOPIRAMATE 100 mg/1 | Jul 15, 2026 | Sep 3, 2026 |
| Remedyrepack Inc. | TOPIRAMATE 25 mg/1 | Jul 15, 2026 | Sep 3, 2026 |
| St. Mary's Medical Park Pharmacy | TOPIRAMATE 25 mg/1 | Jul 15, 2026 | Sep 3, 2026 |
| Sun Pharmaceutical Industries, Inc. | TOPIRAMATE 100 mg/1 | Jul 15, 2026 | Sep 3, 2026 |
| Sun Pharmaceutical Industries, Inc. | TOPIRAMATE 25 mg/1 | Jul 15, 2026 | Sep 3, 2026 |
| A-S Medication Solutions | TOPIRAMATE 100 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Advanced Rx of Tennessee, LLC | TOPIRAMATE 25 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Advanced Rx of Tennessee, LLC | TOPIRAMATE 50 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Advanced Rx Pharmacy of Tennessee, LLC | TOPIRAMATE 25 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| American Health Packaging | TOPIRAMATE 25 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| American Health Packaging | TOPIRAMATE 200 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| American Health Packaging | TOPIRAMATE 100 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| American Health Packaging | TOPIRAMATE 50 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| AvPAK | TOPIRAMATE 200 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| AvPAK | TOPIRAMATE 100 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| AvPAK | TOPIRAMATE 25 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| AvPAK | TOPIRAMATE 50 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Cardinal Health 107, LLC | TOPIRAMATE 100 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Cardinal Health 107, LLC | TOPIRAMATE 25 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Coupler LLC | TOPIRAMATE 50 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Glenmark Pharmaceuticals Inc., USA | TOPIRAMATE 100 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Glenmark Pharmaceuticals Inc., USA | TOPIRAMATE 200 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Glenmark Pharmaceuticals Inc., USA | TOPIRAMATE 25 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Glenmark Pharmaceuticals Inc., USA | TOPIRAMATE 50 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Major Pharmaceuticals | TOPIRAMATE 100 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Major Pharmaceuticals | TOPIRAMATE 25 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| NCS HealthCare of KY, LLC dba Vangard Labs | TOPIRAMATE 50 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
Roster from daily NDC Directory diffs — first/last seen dates start July 2026.
DrugDashboards, "topiramate — NDC 67046-0357-03," retrieved September 3, 2026, https://drugdashboards.com/drug/67046035703.
Free to cite with attribution — see how the data is put together.