DrugDashboards

Topiramate

Topiramate · TOPIRAMATE 25 mg/1 · Tablet, Film Coated · Oral · Glenmark Pharmaceuticals Inc., USA

NDC 68462-0108-05 · 500 TABLET, FILM COATED in 1 BOTTLE · ANDA · View full market →

The short version

18 companies supply this market — deep enough that no single failure threatens the supply. The price has held steady around $0.0256 per unit over the past year. Put together: this looks like a healthy supply — the boring kind, which is exactly what you want.

The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.

One drug, every price

The same NDC has different prices depending on who is paying. Units differ between rungs — compare within a rung over time, not rung against rung, unless the units match.

ⓘ How this was built
Data sources
  • CMS NADAC (pharmacy acquisition, weekly)
  • CMS Part B ASP quarterly payment limits
  • CMS Maximum Fair Prices (IRA negotiated, NDC-level)
  • Medicare Part D Spending by Drug (data.cms.gov, name-matched)
  • VA FSS / Big4 federal contract prices (va.gov, twice monthly)
  • ACA Federal Upper Limits + weighted AMP (data.medicaid.gov, monthly)
  • California SB-17 WAC filings (list price, per package)
Method

Each rung is the newest figure for this NDC from one federal price system, shown with its own unit. Part D is matched by drug name because CMS publishes no NDCs there; it is gross spending, before confidential rebates.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

  • Pharmacies pay (NADAC)$0.0256per EAinvoice-surveyed acquisition cost · Aug 19, 2026
  • Part D plans paid (avg)$0.1222per dosage unitgross, before rebates — matched by drug name · 2024
  • Medicaid generic ceiling (FUL)$0.0479per TABweighted avg manufacturer price $0.0274 · Aug 1, 2026187% of what pharmacies pay — higher than 86% of drugs with this benchmark

Medicare Part D

All Part D pricing →

Matched to CMS's representative package for this drug (NDC 68382-0138-05) — same generic, strength, and dosage form. CMS prices one NDC per drug concept, not every package.

ⓘ How this was built
Data sources
  • CMS quarterly Prescription Drug Plan Formulary & Pricing files (SPUF)
Method

Negotiated 30-day point-of-sale unit prices and formulary terms aggregated across every unsuppressed Part D and MA-PD plan for the quarter shown. Point of sale means gross of confidential rebates. CMS publishes one representative NDC per drug concept (RxCUI) rather than every package, so these figures come from CMS's representative package for the same drug — matched on generic name, strength, and dosage form. Estimated from MedPAC's program-wide rebate aggregates (June 2023: DIR = 29% of gross Part D spending; brand rebates ≈ 25–40% of gross, generics minimal). Actual rebates are confidential and vary widely by drug — this is a range, not a fact about this drug.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

Plans pay at point of sale
$0.0816per unit
middle half $0.0609$0.1538 · 5,496 plans · Apr 1, 2026
Est. net of rebates
≈ $0.0816
generic — rebates are minimal, so net ≈ gross
Coverage & restrictions
100%of plans cover it
tier 2 · prior auth 7% · step therapy 0% · qty limit 12%

*No drug-level rebate is public — the estimate applies MedPAC's program-wide brand rebate range to this drug's gross price. Tracked here for 10 quarters since 2024.

NADAC price per unit

$0$0.05$0.1$0.15Dec 2020Sep 2026$0.0256
70 price points · per EA · dashed = manufacturer avg (WAMP)Source: CMS NADAC

Estimated fill cost

#30 count
$0.77
#90 count
$2.31

Estimates: latest NADAC unit price × quantity. Pharmacy acquisition cost only — excludes dispensing fees, markup, and insurance terms.

Medicaid spend (2025)

$611,886
58,867 prescriptions paid by Medicaid nationally · all Medicaid spend →

Supply fragility

0Low risk

Nothing here is signaling trouble: several manufacturers, no current shortage, no recent serious recalls, stable pricing. In drug supply, boring is the good outcome.

The score counts pressure that is already visible — fewer makers, shortages, recalls, falling prices. 0 means none of it; 100 means all of it at once. Recomputed daily · as of Sep 3, 2026

90-day shortage risk (model v2)

0.1%chance of a new FDA shortage posting for topiramate (oral solid) in the next 90 days

OAI inspection at a producing facility (24 months) · sole-source market

For scale: the typical drug’s chance is about 0.1% — this one is in ordinary territory.

Backtested statistical model over the whole market, not this package alone. Model details →

Where it's made

Establishments this product's FDA label declares, located via FDA registration data. How we built this →

Regulatory

Application
ANDA077627
TE code
AB
Approval date
Mar 27, 2009
Patents / exclusivity
None on file

Shortage history

No FDA shortage reports for this drug or its presentations.

Recalls (this NDC)

  • Class III · TerminatedApr 5, 2013
    Glenmark Generics Inc., USAChemical Contamination: Topiramate Tablets is being recalled due to complaints related to an off - odor. described as moldy, musty or fishy in nature.

Manufacturers of Topiramate (Tablet, Film Coated)

LabelerStrengthFirst seenLast seen
A-S Medication SolutionsTOPIRAMATE 50 mg/1Jul 15, 2026Sep 3, 2026
Aurobindo Pharma LimitedTOPIRAMATE 50 mg/1Jul 15, 2026Sep 3, 2026
Aurobindo Pharma LimitedTOPIRAMATE 200 mg/1Jul 15, 2026Sep 3, 2026
Bryant Ranch PrepackTOPIRAMATE 25 mg/1Jul 15, 2026Sep 3, 2026
Bryant Ranch PrepackTOPIRAMATE 100 mg/1Jul 15, 2026Sep 3, 2026
Bryant Ranch PrepackTOPIRAMATE 50 mg/1Jul 15, 2026Sep 3, 2026
Bryant Ranch PrepackTOPIRAMATE 200 mg/1Jul 15, 2026Sep 3, 2026
Coupler LLCTOPIRAMATE 25 mg/1Jul 15, 2026Sep 3, 2026
NuCare Pharmaceuticals,Inc.TOPIRAMATE 50 mg/1Jul 15, 2026Sep 3, 2026
PD-Rx Pharmaceuticals, Inc.TOPIRAMATE 50 mg/1Jul 15, 2026Sep 3, 2026
PD-Rx Pharmaceuticals, Inc.TOPIRAMATE 25 mg/1Jul 15, 2026Sep 3, 2026
Proficient Rx LPTOPIRAMATE 50 mg/1Jul 15, 2026Sep 3, 2026
Proficient Rx LPTOPIRAMATE 100 mg/1Jul 15, 2026Sep 3, 2026
Remedyrepack Inc.TOPIRAMATE 100 mg/1Jul 15, 2026Sep 3, 2026
Remedyrepack Inc.TOPIRAMATE 25 mg/1Jul 15, 2026Sep 3, 2026
St. Mary's Medical Park PharmacyTOPIRAMATE 25 mg/1Jul 15, 2026Sep 3, 2026
Sun Pharmaceutical Industries, Inc.TOPIRAMATE 100 mg/1Jul 15, 2026Sep 3, 2026
Sun Pharmaceutical Industries, Inc.TOPIRAMATE 25 mg/1Jul 15, 2026Sep 3, 2026
A-S Medication SolutionsTOPIRAMATE 100 mg/1Jul 15, 2026Sep 2, 2026
Advanced Rx of Tennessee, LLCTOPIRAMATE 25 mg/1Jul 15, 2026Sep 2, 2026
Advanced Rx of Tennessee, LLCTOPIRAMATE 50 mg/1Jul 15, 2026Sep 2, 2026
Advanced Rx Pharmacy of Tennessee, LLCTOPIRAMATE 25 mg/1Jul 15, 2026Sep 2, 2026
American Health PackagingTOPIRAMATE 25 mg/1Jul 15, 2026Sep 2, 2026
American Health PackagingTOPIRAMATE 200 mg/1Jul 15, 2026Sep 2, 2026
American Health PackagingTOPIRAMATE 100 mg/1Jul 15, 2026Sep 2, 2026
American Health PackagingTOPIRAMATE 50 mg/1Jul 15, 2026Sep 2, 2026
AvPAKTOPIRAMATE 200 mg/1Jul 15, 2026Sep 2, 2026
AvPAKTOPIRAMATE 100 mg/1Jul 15, 2026Sep 2, 2026
AvPAKTOPIRAMATE 25 mg/1Jul 15, 2026Sep 2, 2026
AvPAKTOPIRAMATE 50 mg/1Jul 15, 2026Sep 2, 2026
Cardinal Health 107, LLCTOPIRAMATE 100 mg/1Jul 15, 2026Sep 2, 2026
Cardinal Health 107, LLCTOPIRAMATE 25 mg/1Jul 15, 2026Sep 2, 2026
Coupler LLCTOPIRAMATE 50 mg/1Jul 15, 2026Sep 2, 2026
Glenmark Pharmaceuticals Inc., USATOPIRAMATE 100 mg/1Jul 15, 2026Sep 2, 2026
Glenmark Pharmaceuticals Inc., USATOPIRAMATE 200 mg/1Jul 15, 2026Sep 2, 2026
Glenmark Pharmaceuticals Inc., USATOPIRAMATE 25 mg/1Jul 15, 2026Sep 2, 2026
Glenmark Pharmaceuticals Inc., USATOPIRAMATE 50 mg/1Jul 15, 2026Sep 2, 2026
Major PharmaceuticalsTOPIRAMATE 100 mg/1Jul 15, 2026Sep 2, 2026
Major PharmaceuticalsTOPIRAMATE 25 mg/1Jul 15, 2026Sep 2, 2026
NCS HealthCare of KY, LLC dba Vangard LabsTOPIRAMATE 50 mg/1Jul 15, 2026Sep 2, 2026

Roster from daily NDC Directory diffs — first/last seen dates start July 2026.

Cite this page

DrugDashboards, "Topiramate — NDC 68462-0108-05," retrieved September 3, 2026, https://drugdashboards.com/drug/68462010805.

Free to cite with attribution — see how the data is put together.