DrugDashboards

Fondaparinux Sodium

fondaparinux sodium · FONDAPARINUX SODIUM 2.5 mg/.5mL · Injection, Solution · Subcutaneous · Mylan Institutional LLC

NDC 67457-0582-10 · 10 SYRINGE, GLASS in 1 CARTON / .5 mL in 1 SYRINGE, GLASS · NDA AUTHORIZED GENERIC · View full market →

The short version

4 companies supply this market — a reasonable cushion if one runs into trouble. The price is down 21% over the past year, to $22.16 per mL. Put together: this looks like a healthy supply — the boring kind, which is exactly what you want. Historically, drugs in this position went on to a new shortage within 90 days about 0.6% of the time — roughly 4× the typical drug (0.1%).

The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.

One drug, every price

The same NDC has different prices depending on who is paying. Units differ between rungs — compare within a rung over time, not rung against rung, unless the units match.

ⓘ How this was built
Data sources
  • CMS NADAC (pharmacy acquisition, weekly)
  • CMS Part B ASP quarterly payment limits
  • CMS Maximum Fair Prices (IRA negotiated, NDC-level)
  • Medicare Part D Spending by Drug (data.cms.gov, name-matched)
  • VA FSS / Big4 federal contract prices (va.gov, twice monthly)
  • ACA Federal Upper Limits + weighted AMP (data.medicaid.gov, monthly)
  • California SB-17 WAC filings (list price, per package)
Method

Each rung is the newest figure for this NDC from one federal price system, shown with its own unit. Part D is matched by drug name because CMS publishes no NDCs there; it is gross spending, before confidential rebates.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

  • Pharmacies pay (NADAC)$22.16per MLinvoice-surveyed acquisition cost · Aug 19, 2026
  • Medicare Part B pays (ASP+6%)$0.9250per billing unit (0.5 MG)HCPCS J1652 · Jul 1, 2026
  • Part D plans paid (avg)$67.45per dosage unitgross, before rebates — matched by drug name · 2024
  • Federal ceiling (Big4)$52.43per package of 10X0.5MLMylan Institutional LLC · Jan 1, 2026

Medicare Part D

All Part D pricing →

Matched to CMS's representative package for this drug (NDC 55150-0230-10) — same generic, strength, and dosage form. CMS prices one NDC per drug concept, not every package.

ⓘ How this was built
Data sources
  • CMS quarterly Prescription Drug Plan Formulary & Pricing files (SPUF)
Method

Negotiated 30-day point-of-sale unit prices and formulary terms aggregated across every unsuppressed Part D and MA-PD plan for the quarter shown. Point of sale means gross of confidential rebates. CMS publishes one representative NDC per drug concept (RxCUI) rather than every package, so these figures come from CMS's representative package for the same drug — matched on generic name, strength, and dosage form. Estimated from MedPAC's program-wide rebate aggregates (June 2023: DIR = 29% of gross Part D spending; brand rebates ≈ 25–40% of gross, generics minimal). Actual rebates are confidential and vary widely by drug — this is a range, not a fact about this drug.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

Plans pay at point of sale
$33.98per unit
middle half $28.79$41.30 · 4,039 plans · Apr 1, 2026
Est. net of rebates
≈ $33.98
generic — rebates are minimal, so net ≈ gross
Coverage & restrictions
73%of plans cover it
tier 4 · prior auth 0% · step therapy 0% · qty limit 20%

*No drug-level rebate is public — the estimate applies MedPAC's program-wide brand rebate range to this drug's gross price. Tracked here for 10 quarters since 2024.

NADAC price per unit

$0$25.00$50.00$75.00Jul 2015Sep 2026$22.16
31 price points · per MLSource: CMS NADAC

Estimated fill cost

WAC per package, as filed
$248.58
Reported to Texas DSHS · 2026 annual filing · Mylan Institutional Inc.

Manufacturer list price as filed — not what pharmacies actually pay after discounts.

Medicare Part B (ASP)

Payment limit per 0.5 MG
$0.925
HCPCS J1652 · Jul 1, 2026 quarter · typically ASP + 6%

Medicaid spend (2025)

$65
15 prescriptions paid by Medicaid nationally · all Medicaid spend →

Supply fragility

15Low risk

Some pressure is visible, but not much — here’s everything the score found to count.

  • 4 active manufacturers+5
  • sterile injectable+10

The score counts pressure that is already visible — fewer makers, shortages, recalls, falling prices. 0 means none of it; 100 means all of it at once. Recomputed daily · as of Sep 3, 2026

90-day shortage risk (model v2)

0.6%chance of a new FDA shortage posting for fondaparinux sodium (injectable) in the next 90 days

sterile injectable · OAI inspection at a producing facility (24 months) · sole-source market

For scale: the typical drug’s chance is about 0.1% — this one is 4× that.

Backtested statistical model over the whole market, not this package alone. Model details →

Is this a "specialty" drug?

There's no legal definition — it meets 2 of 6 public criteria. Why that matters →

  • Part D specialty tier
  • Costs ≥ $950/fill · avg $1,121.26 per prescription
  • Biologic (BLA)
  • Injectable / infused
  • Orphan-drug exclusivity
  • REMS program

Regulatory

Application
NDA021345
TE code
AP
Approval date
Dec 7, 2001
Patents / exclusivity
None on file

Shortage history

No FDA shortage reports for this drug or its presentations.

Recalls (this NDC)

No enforcement reports list this package NDC.

Manufacturers of fondaparinux sodium (Injection, Solution)

LabelerStrengthFirst seenLast seen
Mylan Institutional LLCFONDAPARINUX SODIUM 7.5 mg/.6mLJul 15, 2026Sep 3, 2026
Mylan Institutional LLCFONDAPARINUX SODIUM 2.5 mg/.5mLJul 15, 2026Sep 3, 2026
Mylan Institutional LLCFONDAPARINUX SODIUM 5 mg/.4mLJul 15, 2026Sep 3, 2026
Mylan Institutional LLCFONDAPARINUX SODIUM 10 mg/.8mLJul 15, 2026Sep 3, 2026
Eugia US LLCFONDAPARINUX SODIUM 7.5 mg/.6mLJul 15, 2026Sep 2, 2026
Eugia US LLCFONDAPARINUX SODIUM 5 mg/.4mLJul 15, 2026Sep 2, 2026
Eugia US LLCFONDAPARINUX SODIUM 2.5 mg/.5mLJul 15, 2026Sep 2, 2026
Eugia US LLCFONDAPARINUX SODIUM 10 mg/.8mLJul 15, 2026Sep 2, 2026
Italfarmaco S.p.AFONDAPARINUX SODIUM 7.5 mg/.6mLJul 15, 2026Sep 2, 2026
Italfarmaco S.p.AFONDAPARINUX SODIUM 2.5 mg/.5mLJul 15, 2026Sep 2, 2026
Italfarmaco S.p.AFONDAPARINUX SODIUM 5 mg/.4mLJul 15, 2026Sep 2, 2026
Italfarmaco S.p.AFONDAPARINUX SODIUM 10 mg/.8mLJul 15, 2026Sep 2, 2026
Zydus Pharmaceuticals (USA) Inc.FONDAPARINUX SODIUM 7.5 mg/.6mLJul 15, 2026Sep 2, 2026
Zydus Pharmaceuticals (USA) Inc.FONDAPARINUX SODIUM 2.5 mg/.5mLJul 15, 2026Sep 2, 2026
Zydus Pharmaceuticals (USA) Inc.FONDAPARINUX SODIUM 10 mg/.8mLJul 15, 2026Sep 2, 2026
Zydus Pharmaceuticals (USA) Inc.FONDAPARINUX SODIUM 5 mg/.4mLJul 15, 2026Sep 2, 2026

Roster from daily NDC Directory diffs — first/last seen dates start July 2026.

Cite this page

DrugDashboards, "Fondaparinux Sodium — NDC 67457-0582-10," retrieved September 3, 2026, https://drugdashboards.com/drug/67457058210.

Free to cite with attribution — see how the data is put together.