DrugDashboards

Adapalene

Adapalene · ADAPALENE 3 mg/g · Gel · Topical · Mayne Pharma Commercial LLC.

NDC 68308-0666-45 · 1 BOTTLE, PUMP in 1 CARTON / 45 g in 1 BOTTLE, PUMP · NDA AUTHORIZED GENERIC · View full market →

The short version

31 companies supply this market — deep enough that no single failure threatens the supply. The price is down 19% over the past year, to $0.7822 per gram. Put together: this looks like a healthy supply — the boring kind, which is exactly what you want.

The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.

One drug, every price

The same NDC has different prices depending on who is paying. Units differ between rungs — compare within a rung over time, not rung against rung, unless the units match.

ⓘ How this was built
Data sources
  • CMS NADAC (pharmacy acquisition, weekly)
  • CMS Part B ASP quarterly payment limits
  • CMS Maximum Fair Prices (IRA negotiated, NDC-level)
  • Medicare Part D Spending by Drug (data.cms.gov, name-matched)
  • VA FSS / Big4 federal contract prices (va.gov, twice monthly)
  • ACA Federal Upper Limits + weighted AMP (data.medicaid.gov, monthly)
  • California SB-17 WAC filings (list price, per package)
Method

Each rung is the newest figure for this NDC from one federal price system, shown with its own unit. Part D is matched by drug name because CMS publishes no NDCs there; it is gross spending, before confidential rebates.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

  • Pharmacies pay (NADAC)$0.7822per GMinvoice-surveyed acquisition cost · Aug 19, 2026
  • Part D plans paid (avg)$2.98per dosage unitgross, before rebates — matched by drug name · 2024
  • Federal contracts pay (FSS)$5.33per package of 45GMMayne Pharma Commercial LLC · Jan 1, 2026
  • Medicaid generic ceiling (FUL)$0.7822per GMweighted avg manufacturer price $0.2172 · Aug 1, 2026100% of what pharmacies pay — higher than 10% of drugs with this benchmark

Medicare Part D

All Part D pricing →

Matched to CMS's representative package for this drug (NDC 51672-1377-06) — same generic, strength, and dosage form. CMS prices one NDC per drug concept, not every package.

ⓘ How this was built
Data sources
  • CMS quarterly Prescription Drug Plan Formulary & Pricing files (SPUF)
Method

Negotiated 30-day point-of-sale unit prices and formulary terms aggregated across every unsuppressed Part D and MA-PD plan for the quarter shown. Point of sale means gross of confidential rebates. CMS publishes one representative NDC per drug concept (RxCUI) rather than every package, so these figures come from CMS's representative package for the same drug — matched on generic name, strength, and dosage form. Estimated from MedPAC's program-wide rebate aggregates (June 2023: DIR = 29% of gross Part D spending; brand rebates ≈ 25–40% of gross, generics minimal). Actual rebates are confidential and vary widely by drug — this is a range, not a fact about this drug.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

Plans pay at point of sale
$0.9591per unit
middle half $0.8800$1.12 · 2,499 plans · Apr 1, 2026
Est. net of rebates
≈ $0.9591
generic — rebates are minimal, so net ≈ gross
Coverage & restrictions
45%of plans cover it
tier 3 · prior auth 7% · step therapy 1% · qty limit 50%

*No drug-level rebate is public — the estimate applies MedPAC's program-wide brand rebate range to this drug's gross price. Tracked here for 10 quarters since 2024.

NADAC price per unit

$0$0.5$1.00$1.50Apr 2024Sep 2026$0.7822
29 price points · per GM · dashed = manufacturer avg (WAMP)Source: CMS NADAC

Estimated fill cost

WAC per package, as filed
$488.65
Reported to Texas DSHS · 2026 annual filing · Mayne Pharma Commercial LLC

Manufacturer list price as filed — not what pharmacies actually pay after discounts.

Medicaid spend (2025)

$1,733
32 prescriptions paid by Medicaid nationally · all Medicaid spend →

Supply fragility

8Low risk

Some pressure is visible, but not much — here’s everything the score found to count.

  • price down 21% year over year+8

The score counts pressure that is already visible — fewer makers, shortages, recalls, falling prices. 0 means none of it; 100 means all of it at once. Recomputed daily · as of Sep 3, 2026

90-day shortage risk (model v2)

0.1%chance of a new FDA shortage posting for adapalene (other) in the next 90 days

sole-source market

For scale: the typical drug’s chance is about 0.1% — this one is in ordinary territory.

Backtested statistical model over the whole market, not this package alone. Model details →

Where it's made

Establishments this product's FDA label declares, located via FDA registration data. How we built this →

Regulatory

Application
NDA021753
TE code
AB
Approval date
Jun 19, 2007
Patents / exclusivity
None on file

Shortage history

No FDA shortage reports for this drug or its presentations.

Recalls (this NDC)

No enforcement reports list this package NDC.

Manufacturers of Adapalene (Gel)

LabelerStrengthFirst seenLast seen
LOreal USA Products IncADAPALENE 1 mg/gJul 15, 2026Sep 3, 2026
P & L Development, LLCADAPALENE 1 mg/gJul 15, 2026Sep 3, 2026
Actavis Pharma, Inc.ADAPALENE 3 mg/gJul 15, 2026Sep 2, 2026
Alchemee, LLCADAPALENE .1 g/100gJul 15, 2026Sep 2, 2026
Alembic Pharmaceuticals Inc.ADAPALENE 3 mg/gJul 15, 2026Sep 2, 2026
Alembic Pharmaceuticals LimitedADAPALENE 3 mg/gJul 15, 2026Sep 2, 2026
Amerisource BergenADAPALENE 1 mg/gJul 15, 2026Sep 2, 2026
Cardinal HealthADAPALENE 1 mg/gJul 15, 2026Sep 2, 2026
CVS PharmacyADAPALENE 1 mg/gJul 15, 2026Sep 2, 2026
Cvs Pharmacy, IncADAPALENE 1 mg/gJul 15, 2026Sep 2, 2026
Dolgencorp, Inc. (DOLLAR GENERAL & REXALL)ADAPALENE 1 mg/gJul 15, 2026Sep 2, 2026
Galderma Laboratories, L.P.ADAPALENE 3 mg/gJul 15, 2026Sep 2, 2026
Galderma Laboratories, L.P.ADAPALENE 1 mg/gJul 15, 2026Sep 2, 2026
Little Pharma, Inc.ADAPALENE .1 g/100gJul 15, 2026Sep 2, 2026
Mayne Pharma Commercial LLC.ADAPALENE 3 mg/gJul 15, 2026Sep 2, 2026
Meijer Distribution Inc.ADAPALENE 1 mg/gJul 15, 2026Sep 2, 2026
Meijer, Inc.ADAPALENE 1 mg/gJul 15, 2026Sep 2, 2026
Rite AidADAPALENE 1 mg/gJul 15, 2026Sep 2, 2026
Rugby Laboratories, Inc.ADAPALENE 1 mg/gJul 15, 2026Sep 2, 2026
Safeway, Inc.ADAPALENE 1 mg/gJul 15, 2026Sep 2, 2026
Sun Pharmaceutical Industries, Inc.ADAPALENE 1 mg/gJul 15, 2026Sep 2, 2026
Sun Pharmaceutical Industries, Inc.ADAPALENE 3 mg/gJul 15, 2026Sep 2, 2026
Target CorporationADAPALENE 1 mg/gJul 15, 2026Sep 2, 2026
The Kroger Co.ADAPALENE 1 mg/gJul 15, 2026Sep 2, 2026
TOP CARE (Topco Associates LLC)ADAPALENE 1 mg/gJul 15, 2026Sep 2, 2026
Topco AssociatesADAPALENE 1 mg/gJul 15, 2026Sep 2, 2026
Wal-Mart Stores IncADAPALENE 1 mg/gJul 15, 2026Sep 2, 2026
Crown LaboratoriesADAPALENE 1 mg/gJul 15, 2026Aug 31, 2026
Glenmark Therapeutics Inc., UsaADAPALENE 1 mg/gJul 15, 2026Aug 31, 2026
Kenvue Brands LLCADAPALENE 1 mg/gJul 15, 2026Aug 31, 2026
WalgreensADAPALENE 1 mg/gJul 15, 2026Aug 31, 2026
Yyba CorpADAPALENE 1 mg/gJul 15, 2026Aug 31, 2026
YYBA CorpADAPALENE 1 mg/gJul 15, 2026Aug 28, 2026

Roster from daily NDC Directory diffs — first/last seen dates start July 2026.

Cite this page

DrugDashboards, "Adapalene — NDC 68308-0666-45," retrieved September 3, 2026, https://drugdashboards.com/drug/68308066645.

Free to cite with attribution — see how the data is put together.