DrugDashboards

bupropion

bupropion · BUPROPION HYDROCHLORIDE 150 mg/1 · Tablet, Extended Release · Oral · Zydus Pharmaceuticals USA Inc.

NDC 68382-0353-05 · 500 TABLET, EXTENDED RELEASE in 1 BOTTLE · ANDA · View full market →

The short version

Just 3 companies supply this market — thin enough that a single exit would be felt immediately. The price is down 23% over the past year, to $0.0787 per unit. Put together: this looks like a healthy supply — the boring kind, which is exactly what you want.

The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.

One drug, every price

The same NDC has different prices depending on who is paying. Units differ between rungs — compare within a rung over time, not rung against rung, unless the units match.

ⓘ How this was built
Data sources
  • CMS NADAC (pharmacy acquisition, weekly)
  • CMS Part B ASP quarterly payment limits
  • CMS Maximum Fair Prices (IRA negotiated, NDC-level)
  • Medicare Part D Spending by Drug (data.cms.gov, name-matched)
  • VA FSS / Big4 federal contract prices (va.gov, twice monthly)
  • ACA Federal Upper Limits + weighted AMP (data.medicaid.gov, monthly)
  • California SB-17 WAC filings (list price, per package)
Method

Each rung is the newest figure for this NDC from one federal price system, shown with its own unit. Part D is matched by drug name because CMS publishes no NDCs there; it is gross spending, before confidential rebates.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

  • Pharmacies pay (NADAC)$0.0787per EAinvoice-surveyed acquisition cost · Aug 19, 2026
  • Medicaid generic ceiling (FUL)$59.29per TABweighted avg manufacturer price $33.8828 · May 1, 202575324% of what pharmacies pay — higher than 95% of drugs with this benchmark

Medicare Part D

No Medicare Part D plan in CMS's quarterly files lists this product. That usually means it is discontinued, a repackager's listing, or a product no plan has added to its formulary.

How Part D pricing works →

NADAC price per unit

$0$20.00$40.00$60.00Mar 2019Sep 2026$0.0787
91 price points · per EA · dashed = manufacturer avg (WAMP)Source: CMS NADAC

Estimated fill cost

#30 count
$2.36
#90 count
$7.08

Estimates: latest NADAC unit price × quantity. Pharmacy acquisition cost only — excludes dispensing fees, markup, and insurance terms.

Medicaid spend (2025)

$4,528
268 prescriptions paid by Medicaid nationally · all Medicaid spend →

Supply fragility

18Low risk

Some pressure is visible, but not much — here’s everything the score found to count.

  • 3 active manufacturers+10
  • price down 22% year over year+8

The score counts pressure that is already visible — fewer makers, shortages, recalls, falling prices. 0 means none of it; 100 means all of it at once. Recomputed daily · as of Sep 3, 2026

90-day shortage risk (model v2)

0.1%chance of a new FDA shortage posting for bupropion (oral solid) in the next 90 days

sole-source market

For scale: the typical drug’s chance is about 0.1% — this one is in ordinary territory.

Backtested statistical model over the whole market, not this package alone. Model details →

Where it's made

Establishments this product's FDA label declares, located via FDA registration data. How we built this →

Regulatory

Application
ANDA201567
TE code
AB3
Approval date
Jan 17, 2014
Patents / exclusivity
None on file

Shortage history

No FDA shortage reports for this drug or its presentations.

Recalls (this NDC)

  • Class III · TerminatedNov 2, 2016
    Zydus Pharmaceuticals USA IncFailed Dissolution Specifications; 6 month time point
  • Class III · TerminatedAug 3, 2016
    Zydus Pharmaceuticals USA IncFailed Dissolution Specifications: Product did not meet dissolution specification at an intermediate time point.

Manufacturers of bupropion (Tablet, Extended Release)

LabelerStrengthFirst seenLast seen
Proficient Rx LPBUPROPION HYDROCHLORIDE 300 mg/1Jul 15, 2026Sep 2, 2026
Zydus Lifesciences LimitedBUPROPION HYDROCHLORIDE 150 mg/1Jul 15, 2026Sep 2, 2026
Zydus Lifesciences LimitedBUPROPION HYDROCHLORIDE 300 mg/1Jul 15, 2026Sep 2, 2026
Zydus Pharmaceuticals USA Inc.BUPROPION HYDROCHLORIDE 150 mg/1Jul 15, 2026Sep 2, 2026
Zydus Pharmaceuticals USA Inc.BUPROPION HYDROCHLORIDE 300 mg/1Jul 15, 2026Sep 2, 2026

Roster from daily NDC Directory diffs — first/last seen dates start July 2026.

Cite this page

DrugDashboards, "bupropion — NDC 68382-0353-05," retrieved September 3, 2026, https://drugdashboards.com/drug/68382035305.

Free to cite with attribution — see how the data is put together.