DrugDashboards

Derma-Smoothe/FS

fluocinolone acetonide · FLUOCINOLONE ACETONIDE .11 mg/mL · Oil · Topical · Royal Pharmaceuticals, LLC

NDC 68791-0101-04 · 1 BOTTLE in 1 CARTON / 118.28 mL in 1 BOTTLE · NDA · View full market →

The short version

12 companies supply this market — deep enough that no single failure threatens the supply. The brand price is down 18% over the past year, to $0.2424 per mL. Put together: this looks like a healthy supply — the boring kind, which is exactly what you want.

The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.

One drug, every price

The same NDC has different prices depending on who is paying. Units differ between rungs — compare within a rung over time, not rung against rung, unless the units match.

ⓘ How this was built
Data sources
  • CMS NADAC (pharmacy acquisition, weekly)
  • CMS Part B ASP quarterly payment limits
  • CMS Maximum Fair Prices (IRA negotiated, NDC-level)
  • Medicare Part D Spending by Drug (data.cms.gov, name-matched)
  • VA FSS / Big4 federal contract prices (va.gov, twice monthly)
  • ACA Federal Upper Limits + weighted AMP (data.medicaid.gov, monthly)
  • California SB-17 WAC filings (list price, per package)
Method

Each rung is the newest figure for this NDC from one federal price system, shown with its own unit. Part D is matched by drug name because CMS publishes no NDCs there; it is gross spending, before confidential rebates.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

  • Pharmacies pay (NADAC)$0.2424per MLinvoice-surveyed acquisition cost · Aug 19, 2026
  • Part D plans paid (avg)$0.3149per dosage unitgross, before rebates — matched by drug name · 2024
  • Federal contracts pay (FSS)$26.55per package of 118.28MLRoyal Pharmaceuticals, LLC · Jan 1, 2026
  • Medicaid generic ceiling (FUL)$0.2144per MLweighted avg manufacturer price $0.1225 · Aug 1, 202688% of what pharmacies pay — a deeper discount than 95% of drugs with this benchmark

Medicare Part D

All Part D pricing →

Matched to CMS's representative package for this drug (NDC 64980-0329-20) — same generic, strength, and dosage form. CMS prices one NDC per drug concept, not every package.

ⓘ How this was built
Data sources
  • CMS quarterly Prescription Drug Plan Formulary & Pricing files (SPUF)
Method

Negotiated 30-day point-of-sale unit prices and formulary terms aggregated across every unsuppressed Part D and MA-PD plan for the quarter shown. Point of sale means gross of confidential rebates. CMS publishes one representative NDC per drug concept (RxCUI) rather than every package, so these figures come from CMS's representative package for the same drug — matched on generic name, strength, and dosage form. Estimated from MedPAC's program-wide rebate aggregates (June 2023: DIR = 29% of gross Part D spending; brand rebates ≈ 25–40% of gross, generics minimal). Actual rebates are confidential and vary widely by drug — this is a range, not a fact about this drug.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

Plans pay at point of sale
$1.73per unit
middle half $1.47$2.33 · 5,292 plans · Apr 1, 2026
Est. net of rebates
$1.04–$1.30
brand drug — est. 25-40% rebate off the price at left
Coverage & restrictions
96%of plans cover it
tier 3 · prior auth 0% · step therapy 0% · qty limit 0%

*No drug-level rebate is public — the estimate applies MedPAC's program-wide brand rebate range to this drug's gross price. Tracked here for 1 quarter since 2024.

NADAC price per unit

$0$1.00$2.00$3.00Jan 2014Sep 2026$0.2424
41 price points · per ML · dashed = manufacturer avg (WAMP)Source: CMS NADAC

Estimated fill cost

Estimated WAC per mLestimate
$0.25
No Texas or California filing exists for this NDC — this figure is derived, not filed.

This is an ESTIMATE derived from NADAC, not a filed or published price: pharmacies typically acquire brand drugs at roughly 2–4% below list, so list ≈ NADAC ÷ 0.97. Shown only because no state transparency filing exists for this NDC.

Medicaid spend (2025)

$2.6M
68,698 prescriptions paid by Medicaid nationally · all Medicaid spend →

Supply fragility

0Low risk

Nothing here is signaling trouble: several manufacturers, no current shortage, no recent serious recalls, stable pricing. In drug supply, boring is the good outcome.

The score counts pressure that is already visible — fewer makers, shortages, recalls, falling prices. 0 means none of it; 100 means all of it at once. Recomputed daily · as of Sep 3, 2026

90-day shortage risk (model v2)

0.1%chance of a new FDA shortage posting for fluocinolone acetonide (other) in the next 90 days

sole-source market

For scale: the typical drug’s chance is about 0.1% — this one is in ordinary territory.

Backtested statistical model over the whole market, not this package alone. Model details →

Regulatory

Application
NDA019452
TE code
AT
Approval date
Feb 3, 1988
Patents / exclusivity
None on file

Shortage history

No FDA shortage reports for this drug or its presentations.

Recalls (this NDC)

  • Class III · TerminatedJan 31, 2014
    Hill Dermaceuticals, Inc.Subpotent Drug: The active ingredient, fluocinolone acetonide, was found to be subpotent during the firm's routine testing.

Manufacturers of fluocinolone acetonide (Oil)

LabelerStrengthFirst seenLast seen
Bryant Ranch PrepackFLUOCINOLONE ACETONIDE .11 mg/mLJul 15, 2026Sep 3, 2026
Bryant Ranch PrepackFLUOCINOLONE ACETONIDE .01 mg/100mLJul 15, 2026Sep 3, 2026
Padagis Israel Pharmaceuticals LtdFLUOCINOLONE ACETONIDE .01 mg/100mLJul 15, 2026Sep 3, 2026
Quagen Pharmaceuticals LLCFLUOCINOLONE ACETONIDE .11 mg/mLJul 15, 2026Sep 3, 2026
Rising Pharma Holdings, Inc.FLUOCINOLONE ACETONIDE .11 mg/mLJul 15, 2026Sep 3, 2026
Royal PharmaceuticalsFLUOCINOLONE ACETONIDE .11 mg/mLJul 15, 2026Sep 3, 2026
A-S Medication SolutionsFLUOCINOLONE ACETONIDE .11 mg/mLJul 15, 2026Sep 2, 2026
A-S Medication SolutionsFLUOCINOLONE ACETONIDE .01 mg/100mLJul 15, 2026Sep 2, 2026
Amneal Pharmaceuticals LLCFLUOCINOLONE ACETONIDE .11 mg/118.28mLJul 15, 2026Sep 2, 2026
Padagis Israel Pharmaceuticals LtdFLUOCINOLONE ACETONIDE .11 mg/mLJul 15, 2026Sep 2, 2026
Patrin Pharma, Inc.FLUOCINOLONE ACETONIDE .11 mg/mLJul 15, 2026Sep 2, 2026
Rising Pharma Holdings, Inc.FLUOCINOLONE ACETONIDE .11 mg/mLJul 15, 2026Sep 2, 2026
Royal Pharmaceuticals, LLCFLUOCINOLONE ACETONIDE .11 mg/mLJul 15, 2026Sep 2, 2026
Glenmark Pharmaceuticals Inc., USAFLUOCINOLONE ACETONIDE .11 mg/mLJul 15, 2026Aug 31, 2026
Sun Pharmaceutical Industries, Inc.FLUOCINOLONE ACETONIDE .11 mg/118.28mLJul 15, 2026Aug 31, 2026

Roster from daily NDC Directory diffs — first/last seen dates start July 2026.

Cite this page

DrugDashboards, "Derma-Smoothe/FS — NDC 68791-0101-04," retrieved September 3, 2026, https://drugdashboards.com/drug/68791010104.

Free to cite with attribution — see how the data is put together.