The short version
16 companies supply this market — deep enough that no single failure threatens the supply.
The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.
Headache Relief Extra Strength
Acetaminophen, Aspirin and Caffeine · ACETAMINOPHEN 250 mg/1; ASPIRIN 250 mg/1; CAFFEINE 65 mg/1 · Tablet, Film Coated · Oral · Allegiant Health
NDC 69168-0285-26 · 1 BOTTLE in 1 CARTON / 20 TABLET, FILM COATED in 1 BOTTLE · OTC MONOGRAPH DRUG · View full market →
Medicare Part D
Medicare Part D does not cover over-the-counter drugs — by law it pays only for products requiring a prescription.
How Part D pricing works →NADAC price per unit
No NADAC pricing on file for this NDC — NADAC covers drugs dispensed by retail community pharmacies.
Supply fragility
Not scored — fragility is computed for NADAC-priced NDCs.
90-day shortage risk (model v2)
0.1%chance of a new FDA shortage posting for acetaminophen, aspirin, caffeine (oral solid) in the next 90 days
sole-source market
For scale: the typical drug’s chance is about 0.1% — this one is in ordinary territory.
Backtested statistical model over the whole market, not this package alone. Model details →
Is this a "specialty" drug?
There's no legal definition — it meets 1 of 6 public criteria. Why that matters →
- Part D specialty tier
- Costs ≥ $950/fill
- Biologic (BLA)
- Injectable / infused
- Orphan-drug exclusivity
- REMS program · Opioid Analgesic REMS Shared System REMS
Regulatory
- Application
- M013
- TE code
- —
- Approval date
- Jan 14, 1998
- Patents / exclusivity
- None on file
Shortage history
No FDA shortage reports for this drug or its presentations.
Recalls (this NDC)
No enforcement reports list this package NDC.
Manufacturers of Acetaminophen, Aspirin and Caffeine (Tablet, Film Coated)
| Labeler | Strength | First seen | Last seen |
|---|---|---|---|
| Aurohealth LLC | ACETAMINOPHEN 250 mg/1; ASPIRIN 250 mg/1; CAFFEINE 65 mg/1 | Jul 15, 2026 | Sep 3, 2026 |
| Salado Sales, Inc. | ACETAMINOPHEN 250 mg/1; ASPIRIN 250 mg/1; CAFFEINE 65 mg/1 | Jul 15, 2026 | Sep 3, 2026 |
| Wal-Mart Stores Inc | ACETAMINOPHEN 250 mg/1; ASPIRIN 250 mg/1; CAFFEINE 65 mg/1 | Jul 15, 2026 | Sep 3, 2026 |
| Allegiant Health | ACETAMINOPHEN 250 mg/1; ASPIRIN 250 mg/1; CAFFEINE 65 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Amazon.com Services LLC | ACETAMINOPHEN 250 mg/1; ASPIRIN 250 mg/1; CAFFEINE 65 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Aurobindo Pharma Limited | ACETAMINOPHEN 250 mg/1; ASPIRIN 250 mg/1; CAFFEINE 65 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Better Living Brands, LLC | ACETAMINOPHEN 250 mg/1; ASPIRIN 250 mg/1; CAFFEINE 65 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Chain Drug Marketing Association Inc | ACETAMINOPHEN 250 mg/1; ASPIRIN 250 mg/1; CAFFEINE 65 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| CVS Pharmacy | ACETAMINOPHEN 250 mg/1; ASPIRIN 250 mg/1; CAFFEINE 65 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Geri-Care Pharmaceutical Corp | ACETAMINOPHEN 250 mg/1; ASPIRIN 250 mg/1; CAFFEINE 65 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Grocery Outlet | ACETAMINOPHEN 250 mg/1; ASPIRIN 250 mg/1; CAFFEINE 65 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Proficient Rx LP | ACETAMINOPHEN 250 mg/1; ASPIRIN 250 mg/1; CAFFEINE 65 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Rite Aid Corporation | ACETAMINOPHEN 250 mg/1; ASPIRIN 250 mg/1; CAFFEINE 65 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Time Cap Labs | ACETAMINOPHEN 250 mg/1; ASPIRIN 250 mg/1; CAFFEINE 65 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Valu Merchandisers Company | ACETAMINOPHEN 250 mg/1; ASPIRIN 250 mg/1; CAFFEINE 65 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Walmart Inc. | ACETAMINOPHEN 250 mg/1; ASPIRIN 250 mg/1; CAFFEINE 65 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
Roster from daily NDC Directory diffs — first/last seen dates start July 2026.
Cite this page
DrugDashboards, "Headache Relief Extra Strength — NDC 69168-0285-26," retrieved September 3, 2026, https://drugdashboards.com/drug/69168028526.
Free to cite with attribution — see how the data is put together.