DrugDashboards

Naloxone Hydrochloride

Naloxone Hydrochloride · NALOXONE HYDROCHLORIDE 4 mg/.1mL · Spray · Nasal · Amneal Pharmaceuticals LLC

NDC 69238-2104-07 · 2 VIAL, SINGLE-DOSE in 1 CARTON / .1 mL in 1 VIAL, SINGLE-DOSE · ANDA · View full market →

The short version

16 companies supply this market — deep enough that no single failure threatens the supply. The price has fallen 34% in a year, to $16.92 per unit — and generics that get this cheap tend to get abandoned rather than defended. Put together: this looks like a healthy supply — the boring kind, which is exactly what you want.

The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.

One drug, every price

The same NDC has different prices depending on who is paying. Units differ between rungs — compare within a rung over time, not rung against rung, unless the units match.

ⓘ How this was built
Data sources
  • CMS NADAC (pharmacy acquisition, weekly)
  • CMS Part B ASP quarterly payment limits
  • CMS Maximum Fair Prices (IRA negotiated, NDC-level)
  • Medicare Part D Spending by Drug (data.cms.gov, name-matched)
  • VA FSS / Big4 federal contract prices (va.gov, twice monthly)
  • ACA Federal Upper Limits + weighted AMP (data.medicaid.gov, monthly)
  • California SB-17 WAC filings (list price, per package)
Method

Each rung is the newest figure for this NDC from one federal price system, shown with its own unit. Part D is matched by drug name because CMS publishes no NDCs there; it is gross spending, before confidential rebates.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

  • Pharmacies pay (NADAC)$16.92per EAinvoice-surveyed acquisition cost · Aug 19, 2026
  • Federal contracts pay (FSS)$15.56per unitAmneal Pharmaceuticals of New York, LLC · Jun 9, 202592% of what pharmacies pay — a deeper discount than 52% of drugs with this benchmark

Medicare Part D

No Medicare Part D plan in CMS's quarterly files lists this product. That usually means it is discontinued, a repackager's listing, or a product no plan has added to its formulary.

How Part D pricing works →

NADAC price per unit

$0$20.00$40.00Jul 2024Sep 2026$16.92
23 price points · per EASource: CMS NADAC

Estimated fill cost

WAC per package, as filed
$52.00
Reported to Texas DSHS · 2026 annual filing · Amneal Pharmaceuticals LLC

Manufacturer list price as filed — not what pharmacies actually pay after discounts.

Medicaid spend (2025)

$221,584
3,745 prescriptions paid by Medicaid nationally · all Medicaid spend →

Supply fragility

8Low risk

Some pressure is visible, but not much — here’s everything the score found to count.

  • price down 27% year over year+8

The score counts pressure that is already visible — fewer makers, shortages, recalls, falling prices. 0 means none of it; 100 means all of it at once. Recomputed daily · as of Sep 3, 2026

90-day shortage risk (model v2)

0.1%chance of a new FDA shortage posting for naloxone hydrochloride (other) in the next 90 days

OAI inspection at a producing facility (24 months) · sole-source market

For scale: the typical drug’s chance is about 0.1% — this one is in ordinary territory.

Backtested statistical model over the whole market, not this package alone. Model details →

Regulatory

Application
ANDA217992
TE code
Approval date
Apr 23, 2024
Patents / exclusivity
None on file

Shortage history

No FDA shortage reports for this drug or its presentations.

Recalls (this NDC)

No enforcement reports list this package NDC.

Manufacturers of Naloxone Hydrochloride (Spray)

LabelerStrengthFirst seenLast seen
A-S Medication SolutionsNALOXONE HYDROCHLORIDE 4 mg/.1mLJul 15, 2026Sep 3, 2026
Amneal Pharmaceuticals LLCNALOXONE HYDROCHLORIDE 4 mg/.1mLAug 27, 2026Sep 3, 2026
Advanced Rx of Tennessee, LLCNALOXONE HYDROCHLORIDE 4 mg/.1mLJul 15, 2026Sep 2, 2026
Amerisource BergenNALOXONE HYDROCHLORIDE 4 mg/.1mLJul 15, 2026Sep 2, 2026
AvKARENALOXONE HYDROCHLORIDE 4 mg/.1mLJul 15, 2026Sep 2, 2026
BluePoint LaboratoriesNALOXONE HYDROCHLORIDE 4 mg/.1mLJul 15, 2026Sep 2, 2026
Bryant Ranch PrepackNALOXONE HYDROCHLORIDE 4 mg/.1mLJul 15, 2026Sep 2, 2026
CVS Pharmacy, IncNALOXONE HYDROCHLORIDE 4 mg/.1mLJul 15, 2026Sep 2, 2026
Harm Reduction Therapeutics, Inc.NALOXONE HYDROCHLORIDE 3 mg/.1mLJul 15, 2026Sep 2, 2026
HF Acquisition Co LLC, DBA HealthFirstNALOXONE HYDROCHLORIDE 4 mg/.1mLJul 15, 2026Sep 2, 2026
International Medication Systems, Ltd.NALOXONE HYDROCHLORIDE 4 mg/.25mLJul 15, 2026Sep 2, 2026
Padagis Israel Pharmaceuticals LtdNALOXONE HYDROCHLORIDE 4 mg/.1mLJul 15, 2026Sep 2, 2026
Strategic Sourcing Services LLCNALOXONE HYDROCHLORIDE 4 mg/.1mLJul 15, 2026Sep 2, 2026
Walgreen Co.NALOXONE HYDROCHLORIDE 4 mg/.1mLJul 15, 2026Sep 2, 2026
Proficient Rx LPNALOXONE HYDROCHLORIDE 4 mg/.1mLJul 15, 2026Aug 28, 2026
Amneal Pharmaceuticals NY LLCNALOXONE HYDROCHLORIDE 4 mg/.1mLJul 15, 2026Aug 26, 2026

Roster from daily NDC Directory diffs — first/last seen dates start July 2026.

Cite this page

DrugDashboards, "Naloxone Hydrochloride — NDC 69238-2104-07," retrieved September 3, 2026, https://drugdashboards.com/drug/69238210407.

Free to cite with attribution — see how the data is put together.