The short version
Only one company currently supplies this market — there is no backup if it stumbles.
The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.
Pentrexcilina Adult TOTAL RELIEF Multi-Symptom
Acetaminophen, Dextromethorphan Hydrobromide, Guaifenesin USP, Phenylephrine Hydrochloride · PHENYLEPHRINE HYDROCHLORIDE 10 mg/20mL; ACETAMINOPHEN 500 mg/20mL; DEXTROMETHORPHAN HYDROBROMIDE 26.66 mg/20mL; GUAIFENESIN 400 mg/20mL · Syrup · Oral · Opmx Llc
NDC 69729-0790-06 · 1 BOTTLE in 1 CARTON / 177 mL in 1 BOTTLE · OTC MONOGRAPH DRUG · View full market →
Medicare Part D
Medicare Part D does not cover over-the-counter drugs — by law it pays only for products requiring a prescription.
How Part D pricing works →NADAC price per unit
No NADAC pricing on file for this NDC — NADAC covers drugs dispensed by retail community pharmacies.
Supply fragility
Not scored — fragility is computed for NADAC-priced NDCs.
90-day shortage risk (model v2)
0.1%chance of a new FDA shortage posting for acetaminophen, dextromethorphan hydrobromide, guaifenesin, phenylephrine hydrochloride (other) in the next 90 days
sole-source market
For scale: the typical drug’s chance is about 0.1% — this one is in ordinary territory.
Backtested statistical model over the whole market, not this package alone. Model details →
Is this a "specialty" drug?
There's no legal definition — it meets 1 of 6 public criteria. Why that matters →
- Part D specialty tier
- Costs ≥ $950/fill
- Biologic (BLA)
- Injectable / infused
- Orphan-drug exclusivity
- REMS program · Opioid Analgesic REMS Shared System REMS
Regulatory
- Application
- M012
- TE code
- —
- Approval date
- —
- Patents / exclusivity
- None on file
Shortage history
No FDA shortage reports for this drug or its presentations.
Recalls (this NDC)
No enforcement reports list this package NDC.
Manufacturers of Acetaminophen, Dextromethorphan Hydrobromide, Guaifenesin USP, Phenylephrine Hydrochloride (Syrup)
| Labeler | Strength | First seen | Last seen |
|---|---|---|---|
| Opmx Llc | PHENYLEPHRINE HYDROCHLORIDE 10 mg/20mL; ACETAMINOPHEN 500 mg/20mL; DEXTROMETHORPHAN HYDROBROMIDE 26.66 mg/20mL; GUAIFENESIN 400 mg/20mL | Aug 26, 2026 | Sep 2, 2026 |
| Opmx Llc | PHENYLEPHRINE HYDROCHLORIDE 5 mg/10mL; ACETAMINOPHEN 250 mg/10mL; DEXTROMETHORPHAN HYDROBROMIDE 13.33 mg/10mL; GUAIFENESIN 200 mg/10mL | Aug 26, 2026 | Sep 2, 2026 |
| Opmx Llc | PHENYLEPHRINE HYDROCHLORIDE 250 mg/10mL; ACETAMINOPHEN 13.33 mg/10mL; DEXTROMETHORPHAN HYDROBROMIDE 200 mg/10mL; GUAIFENESIN 5 mg/10mL | Jul 22, 2026 | Aug 19, 2026 |
| Opmx Llc | PHENYLEPHRINE HYDROCHLORIDE 500 mg/20mL; ACETAMINOPHEN 26.66 mg/20mL; DEXTROMETHORPHAN HYDROBROMIDE 400 mg/20mL; GUAIFENESIN 10 mg/20mL | Jul 22, 2026 | Aug 19, 2026 |
| Opmx Llc | ACETAMINOPHEN 250 mg/10mL; DEXTROMETHORPHAN HYDROBROMIDE 13.33 mg/10mL; GUAIFENESIN 200 mg/10mL; PHENYLEPHRINE HYDROCHLORIDE 5 mg/10mL | Jul 15, 2026 | Jul 15, 2026 |
| Opmx Llc | ACETAMINOPHEN 500 mg/20mL; DEXTROMETHORPHAN HYDROBROMIDE 26.66 mg/20mL; GUAIFENESIN 400 mg/20mL; PHENYLEPHRINE HYDROCHLORIDE 10 mg/20mL | Jul 15, 2026 | Jul 15, 2026 |
Roster from daily NDC Directory diffs — first/last seen dates start July 2026.
Cite this page
DrugDashboards, "Pentrexcilina Adult TOTAL RELIEF Multi-Symptom — NDC 69729-0790-06," retrieved September 3, 2026, https://drugdashboards.com/drug/69729079006.
Free to cite with attribution — see how the data is put together.