Acetaminophen, Diphenhydramine Hydrochloride · ACETAMINOPHEN 500 mg/1; DIPHENHYDRAMINE HYDROCHLORIDE 25 mg/1 · Tablet, Film Coated · Oral · LEADER/ Cardinal Health 110, Inc.
NDC 70000-0411-03 · 1 BOTTLE in 1 CARTON / 100 TABLET, FILM COATED in 1 BOTTLE · OTC MONOGRAPH DRUG · View full market →
7 companies supply this market — a reasonable cushion if one runs into trouble. The price has held steady around $0.0444 per unit over the past year. Put together: this looks like a healthy supply — the boring kind, which is exactly what you want.
The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.
Medicare Part D does not cover over-the-counter drugs — by law it pays only for products requiring a prescription.
How Part D pricing works →Estimates: latest NADAC unit price × quantity. Pharmacy acquisition cost only — excludes dispensing fees, markup, and insurance terms.
Nothing here is signaling trouble: several manufacturers, no current shortage, no recent serious recalls, stable pricing. In drug supply, boring is the good outcome.
The score counts pressure that is already visible — fewer makers, shortages, recalls, falling prices. 0 means none of it; 100 means all of it at once. Recomputed daily · as of Sep 3, 2026
sole-source market
For scale: the typical drug’s chance is about 0.1% — this one is in ordinary territory.
Backtested statistical model over the whole market, not this package alone. Model details →
There's no legal definition — it meets 1 of 6 public criteria. Why that matters →
No FDA shortage reports for this drug or its presentations.
No enforcement reports list this package NDC.
| Labeler | Strength | First seen | Last seen |
|---|---|---|---|
| Contract Pharmacal Corp. | DIPHENHYDRAMINE HYDROCHLORIDE 50 mg/1; ACETAMINOPHEN 325 mg/1 | Aug 20, 2026 | Sep 3, 2026 |
| JC World Bell Wholesale Co., Inc. | ACETAMINOPHEN 500 mg/1; DIPHENHYDRAMINE HYDROCHLORIDE 25 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Jones Healthcare Group - Packaging Services, Inc | ACETAMINOPHEN 500 mg/1; DIPHENHYDRAMINE HYDROCHLORIDE 25 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| LEADER/ Cardinal Health 110, Inc. | ACETAMINOPHEN 500 mg/1; DIPHENHYDRAMINE HYDROCHLORIDE 25 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Major Pharmaceuticals | DIPHENHYDRAMINE HYDROCHLORIDE 25 mg/1; ACETAMINOPHEN 500 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| Savings Distributors LLC | ACETAMINOPHEN 500 mg/1; DIPHENHYDRAMINE HYDROCHLORIDE 25 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Strive Pharmaceuticals Inc. | ACETAMINOPHEN 500 mg/1; DIPHENHYDRAMINE HYDROCHLORIDE 25 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Contract Pharmacal Corp. | DIPHENHYDRAMINE HYDROCHLORIDE 325 mg/1; ACETAMINOPHEN 50 mg/1 | Jul 22, 2026 | Aug 19, 2026 |
| Major Pharmaceuticals | DIPHENHYDRAMINE HYDROCHLORIDE 500 mg/1; ACETAMINOPHEN 25 mg/1 | Jul 22, 2026 | Aug 19, 2026 |
| Contract Pharmacal Corp. | ACETAMINOPHEN 325 mg/1; DIPHENHYDRAMINE HYDROCHLORIDE 50 mg/1 | Jul 15, 2026 | Jul 15, 2026 |
| Major Pharmaceuticals | ACETAMINOPHEN 500 mg/1; DIPHENHYDRAMINE HYDROCHLORIDE 25 mg/1 | Jul 15, 2026 | Jul 15, 2026 |
Roster from daily NDC Directory diffs — first/last seen dates start July 2026.
DrugDashboards, "Acetaminophen, Diphenhydramine Hydrochloride — NDC 70000-0411-03," retrieved September 3, 2026, https://drugdashboards.com/drug/70000041103.
Free to cite with attribution — see how the data is put together.