DrugDashboards

NightTime Cold and Flu Multi Symptom

Acetaminophen Dextromethorphan Hydrobromide Doxylamine Succinate · ACETAMINOPHEN 325 mg/1; DEXTROMETHORPHAN HYDROBROMIDE 15 mg/1; DOXYLAMINE SUCCINATE 6.25 mg/1 · Capsule, Liquid Filled · Oral · Cardinal Health 110, Llc. Dba Leader 70000

NDC 70000-0516-01 · 16 BLISTER PACK in 1 CARTON / 1 CAPSULE, LIQUID FILLED in 1 BLISTER PACK · OTC MONOGRAPH DRUG · View full market →

The short version

Just 2 companies supply this market — thin enough that a single exit would be felt immediately. The price has held steady around $0.1199 per unit over the past year. Put together: this looks like a healthy supply — the boring kind, which is exactly what you want.

The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.

Medicare Part D

Medicare Part D does not cover over-the-counter drugs — by law it pays only for products requiring a prescription.

How Part D pricing works →

NADAC price per unit

$0$0.1$0.2May 2020Sep 2026$0.1199
77 price points · per EASource: CMS NADAC

Estimated fill cost

#30 count
$3.60
#90 count
$10.79

Estimates: latest NADAC unit price × quantity. Pharmacy acquisition cost only — excludes dispensing fees, markup, and insurance terms.

Supply fragility

20Low risk

Some pressure is visible, but not much — here’s everything the score found to count.

  • 2 active manufacturers+20

The score counts pressure that is already visible — fewer makers, shortages, recalls, falling prices. 0 means none of it; 100 means all of it at once. Recomputed daily · as of Sep 3, 2026

90-day shortage risk (model v2)

0.1%chance of a new FDA shortage posting for acetaminophen, dextromethorphan hydrobromide, doxylamine succinate (oral solid) in the next 90 days

sole-source market · price up 1% YoY

For scale: the typical drug’s chance is about 0.1% — this one is in ordinary territory.

Backtested statistical model over the whole market, not this package alone. Model details →

Is this a "specialty" drug?

There's no legal definition — it meets 1 of 6 public criteria. Why that matters →

  • Part D specialty tier
  • Costs ≥ $950/fill
  • Biologic (BLA)
  • Injectable / infused
  • Orphan-drug exclusivity
  • REMS program · Opioid Analgesic REMS Shared System REMS

Regulatory

Application
M012
TE code
Approval date
Patents / exclusivity
None on file

Shortage history

No FDA shortage reports for this drug or its presentations.

Recalls (this NDC)

No enforcement reports list this package NDC.

Manufacturers of Acetaminophen Dextromethorphan Hydrobromide Doxylamine Succinate (Capsule, Liquid Filled)

LabelerStrengthFirst seenLast seen
Cardinal Health 110, Llc. Dba Leader 70000ACETAMINOPHEN 325 mg/1; DEXTROMETHORPHAN HYDROBROMIDE 15 mg/1; DOXYLAMINE SUCCINATE 6.25 mg/1Jul 15, 2026Sep 2, 2026
WinCo Foods, LLCACETAMINOPHEN 325 mg/1; DEXTROMETHORPHAN HYDROBROMIDE 15 mg/1; DOXYLAMINE SUCCINATE 6.25 mg/1Jul 15, 2026Sep 2, 2026

Roster from daily NDC Directory diffs — first/last seen dates start July 2026.

Cite this page

DrugDashboards, "NightTime Cold and Flu Multi Symptom — NDC 70000-0516-01," retrieved September 3, 2026, https://drugdashboards.com/drug/70000051601.

Free to cite with attribution — see how the data is put together.