DrugDashboards

Leader Daytime Severe Cold and Flu Relief

acetaminophen, dextromethorphan hydrobromide, guaifenesin, phenylephrine hydrochloride · ACETAMINOPHEN 325 mg/1; DEXTROMETHORPHAN HYDROBROMIDE 10 mg/1; GUAIFENESIN 200 mg/1; PHENYLEPHRINE HYDROCHLORIDE 5 mg/1 · Tablet, Film Coated · Oral · Cardinal Health 110, LLC. dba Leader

NDC 70000-0636-01 · 12 BLISTER PACK in 1 CARTON / 2 TABLET, FILM COATED in 1 BLISTER PACK · OTC MONOGRAPH DRUG · View full market →

The short version

15 companies supply this market — deep enough that no single failure threatens the supply. The price has held steady around $0.1412 per unit over the past year. Put together: this looks like a healthy supply — the boring kind, which is exactly what you want.

The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.

Medicare Part D

Medicare Part D does not cover over-the-counter drugs — by law it pays only for products requiring a prescription.

How Part D pricing works →

NADAC price per unit

$0$0.05$0.1$0.15Jul 2024Sep 2026$0.1412
27 price points · per EASource: CMS NADAC

Estimated fill cost

#30 count
$4.24
#90 count
$12.71

Estimates: latest NADAC unit price × quantity. Pharmacy acquisition cost only — excludes dispensing fees, markup, and insurance terms.

Supply fragility

0● Low risk

Nothing here is signaling trouble: several manufacturers, no current shortage, no recent serious recalls, stable pricing. In drug supply, boring is the good outcome.

The score counts pressure that is already visible — fewer makers, shortages, recalls, falling prices. 0 means none of it; 100 means all of it at once. Recomputed daily · as of Sep 3, 2026

90-day shortage risk (model v2)

0.1%chance of a new FDA shortage posting for acetaminophen, dextromethorphan hydrobromide, guaifenesin, and phenylephrine hydrochloride (oral solid) in the next 90 days

price up 11% YoY · sole-source market

For scale: the typical drug’s chance is about 0.1% — this one is in ordinary territory.

Backtested statistical model over the whole market, not this package alone. Model details →

Is this a "specialty" drug?

There's no legal definition — it meets 1 of 6 public criteria. Why that matters →

  • Part D specialty tier
  • Costs ≥ $950/fill
  • Biologic (BLA)
  • Injectable / infused
  • Orphan-drug exclusivity
  • REMS program · Opioid Analgesic REMS Shared System REMS

Regulatory

Application
M012
TE code
—
Approval date
—
Patents / exclusivity
None on file

Shortage history

No FDA shortage reports for this drug or its presentations.

Recalls (this NDC)

No enforcement reports list this package NDC.

Manufacturers of acetaminophen, dextromethorphan hydrobromide, guaifenesin, phenylephrine hydrochloride (Tablet, Film Coated)

LabelerStrengthFirst seenLast seen
Acme UnitedACETAMINOPHEN 325 mg/1; DEXTROMETHORPHAN HYDROBROMIDE 10 mg/1; PHENYLEPHRINE HYDROCHLORIDE 5 mg/1; GUAIFENESIN 100 mg/1Aug 26, 2026Sep 2, 2026
Amazon.com Services LLCACETAMINOPHEN 325 mg/1; DEXTROMETHORPHAN HYDROBROMIDE 10 mg/1; GUAIFENESIN 200 mg/1; PHENYLEPHRINE HYDROCHLORIDE 5 mg/1Jul 15, 2026Sep 2, 2026
Cardinal Health 110, LLC. dba LeaderACETAMINOPHEN 325 mg/1; DEXTROMETHORPHAN HYDROBROMIDE 10 mg/1; GUAIFENESIN 200 mg/1; PHENYLEPHRINE HYDROCHLORIDE 5 mg/1Jul 15, 2026Sep 2, 2026
CVS PharmacyACETAMINOPHEN 325 mg/1; DEXTROMETHORPHAN HYDROBROMIDE 10 mg/1; GUAIFENESIN 200 mg/1; PHENYLEPHRINE HYDROCHLORIDE 5 mg/1Jul 15, 2026Sep 2, 2026
Cvs Woonsocket Prescription Center, IncorporatedACETAMINOPHEN 325 mg/1; DEXTROMETHORPHAN HYDROBROMIDE 10 mg/1; GUAIFENESIN 200 mg/1; PHENYLEPHRINE HYDROCHLORIDE 5 mg/1Jul 15, 2026Sep 2, 2026
Dolgencorp, LLCACETAMINOPHEN 325 mg/1; DEXTROMETHORPHAN HYDROBROMIDE 10 mg/1; GUAIFENESIN 200 mg/1; PHENYLEPHRINE HYDROCHLORIDE 5 mg/1Jul 15, 2026Sep 2, 2026
Jones Healthcare Group - Packaging Services, IncACETAMINOPHEN 325 mg/1; DEXTROMETHORPHAN HYDROBROMIDE 10 mg/1; GUAIFENESIN 200 mg/1; PHENYLEPHRINE HYDROCHLORIDE 5 mg/1Jul 15, 2026Sep 2, 2026
L. Perrigo CompanyACETAMINOPHEN 325 mg/1; DEXTROMETHORPHAN HYDROBROMIDE 10 mg/1; GUAIFENESIN 200 mg/1; PHENYLEPHRINE HYDROCHLORIDE 5 mg/1Jul 15, 2026Sep 2, 2026
Savings Distributors LLCACETAMINOPHEN 325 mg/1; DEXTROMETHORPHAN HYDROBROMIDE 10 mg/1; GUAIFENESIN 200 mg/1; PHENYLEPHRINE HYDROCHLORIDE 5 mg/1Jul 15, 2026Sep 2, 2026
Sportpharm LLCGUAIFENESIN 100 mg/1; DEXTROMETHORPHAN HYDROBROMIDE 10 mg/1; PHENYLEPHRINE HYDROCHLORIDE 5 mg/1; ACETAMINOPHEN 325 mg/1Aug 26, 2026Sep 2, 2026
Sportpharm LLCACETAMINOPHEN 325 mg/1; DEXTROMETHORPHAN HYDROBROMIDE 10 mg/1; GUAIFENESIN 200 mg/1; PHENYLEPHRINE HYDROCHLORIDE 5 mg/1Jul 15, 2026Sep 2, 2026
Strategic Sourcing Services LLCACETAMINOPHEN 325 mg/1; DEXTROMETHORPHAN HYDROBROMIDE 10 mg/1; GUAIFENESIN 200 mg/1; PHENYLEPHRINE HYDROCHLORIDE 5 mg/1Jul 15, 2026Sep 2, 2026
Topco Associates LLCACETAMINOPHEN 325 mg/1; DEXTROMETHORPHAN HYDROBROMIDE 10 mg/1; GUAIFENESIN 200 mg/1; PHENYLEPHRINE HYDROCHLORIDE 5 mg/1Jul 15, 2026Sep 2, 2026
Unifirst First Aid CorporationGUAIFENESIN 100 mg/1; PHENYLEPHRINE HYDROCHLORIDE 5 mg/1; ACETAMINOPHEN 325 mg/1; DEXTROMETHORPHAN HYDROBROMIDE 10 mg/1Aug 26, 2026Sep 2, 2026
Unifirst First Aid CorporationGUAIFENESIN 100 mg/1; DEXTROMETHORPHAN HYDROBROMIDE 10 mg/1; PHENYLEPHRINE HYDROCHLORIDE 5 mg/1; ACETAMINOPHEN 325 mg/1Aug 26, 2026Sep 2, 2026
Wal-Mart Stores IncACETAMINOPHEN 325 mg/1; DEXTROMETHORPHAN HYDROBROMIDE 10 mg/1; GUAIFENESIN 200 mg/1; PHENYLEPHRINE HYDROCHLORIDE 5 mg/1Jul 15, 2026Sep 2, 2026
Unifirst First Aid CorporationPHENYLEPHRINE HYDROCHLORIDE 5 mg/1; ACETAMINOPHEN 325 mg/1; DEXTROMETHORPHAN HYDROBROMIDE 10 mg/1; GUAIFENESIN 100 mg/1Aug 26, 2026Aug 31, 2026
JC World Bell Wholesale Co., Inc.ACETAMINOPHEN 325 mg/1; DEXTROMETHORPHAN HYDROBROMIDE 10 mg/1; GUAIFENESIN 200 mg/1; PHENYLEPHRINE HYDROCHLORIDE 5 mg/1Jul 15, 2026Aug 28, 2026
Unifirst First Aid CorporationPHENYLEPHRINE HYDROCHLORIDE 325 mg/1; ACETAMINOPHEN 10 mg/1; DEXTROMETHORPHAN HYDROBROMIDE 100 mg/1; GUAIFENESIN 5 mg/1Jul 22, 2026Aug 21, 2026
Acme UnitedACETAMINOPHEN 325 mg/1; DEXTROMETHORPHAN HYDROBROMIDE 10 mg/1; PHENYLEPHRINE HYDROCHLORIDE 100 mg/1; GUAIFENESIN 5 mg/1Jul 22, 2026Aug 19, 2026
Sportpharm LLCGUAIFENESIN 325 mg/1; DEXTROMETHORPHAN HYDROBROMIDE 10 mg/1; PHENYLEPHRINE HYDROCHLORIDE 100 mg/1; ACETAMINOPHEN 5 mg/1Jul 22, 2026Aug 19, 2026
Unifirst First Aid CorporationGUAIFENESIN 325 mg/1; DEXTROMETHORPHAN HYDROBROMIDE 10 mg/1; PHENYLEPHRINE HYDROCHLORIDE 100 mg/1; ACETAMINOPHEN 5 mg/1Jul 22, 2026Aug 19, 2026
Unifirst First Aid CorporationGUAIFENESIN 325 mg/1; PHENYLEPHRINE HYDROCHLORIDE 10 mg/1; ACETAMINOPHEN 100 mg/1; DEXTROMETHORPHAN HYDROBROMIDE 5 mg/1Jul 22, 2026Aug 19, 2026
Unifirst First Aid CorporationACETAMINOPHEN 325 mg/1; DEXTROMETHORPHAN HYDROBROMIDE 10 mg/1; GUAIFENESIN 100 mg/1; PHENYLEPHRINE HYDROCHLORIDE 5 mg/1Jul 15, 2026Jul 19, 2026
Acme UnitedACETAMINOPHEN 325 mg/1; DEXTROMETHORPHAN HYDROBROMIDE 10 mg/1; GUAIFENESIN 100 mg/1; PHENYLEPHRINE HYDROCHLORIDE 5 mg/1Jul 15, 2026Jul 15, 2026
Sportpharm LLCACETAMINOPHEN 325 mg/1; DEXTROMETHORPHAN HYDROBROMIDE 10 mg/1; GUAIFENESIN 100 mg/1; PHENYLEPHRINE HYDROCHLORIDE 5 mg/1Jul 15, 2026Jul 15, 2026

Roster from daily NDC Directory diffs — first/last seen dates start July 2026.

Cite this page

DrugDashboards, "Leader Daytime Severe Cold and Flu Relief — NDC 70000-0636-01," retrieved September 3, 2026, https://drugdashboards.com/drug/70000063601.

Free to cite with attribution — see how the data is put together.