The short version
30 companies supply this market — deep enough that no single failure threatens the supply.
The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.
Sulfamethoxazole and Trimethoprim
Sulfamethoxazole and Trimethoprim · SULFAMETHOXAZOLE 400 mg/1; TRIMETHOPRIM 80 mg/1 · Tablet · Oral · Remedyrepack Inc.
NDC 70518-3454-03 · 20 TABLET in 1 BOTTLE, PLASTIC · ANDA · View full market →
Medicare Part D
All Part D pricing →Matched to CMS's representative package for this drug (NDC 49708-0145-01) — same generic, strength, and dosage form. CMS prices one NDC per drug concept, not every package.
ⓘ How this was built
Data sources
- CMS quarterly Prescription Drug Plan Formulary & Pricing files (SPUF)
Method
Negotiated 30-day point-of-sale unit prices and formulary terms aggregated across every unsuppressed Part D and MA-PD plan for the quarter shown. Point of sale means gross of confidential rebates. CMS publishes one representative NDC per drug concept (RxCUI) rather than every package, so these figures come from CMS's representative package for the same drug — matched on generic name, strength, and dosage form. Estimated from MedPAC's program-wide rebate aggregates (June 2023: DIR = 29% of gross Part D spending; brand rebates ≈ 25–40% of gross, generics minimal). Actual rebates are confidential and vary widely by drug — this is a range, not a fact about this drug.
Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.
Plans pay at point of saleⓘ
$1.42per unit
middle half $1.42–$1.42 · 2 plans · Apr 1, 2026
Est. net of rebatesⓘ
≈ $1.42
generic — rebates are minimal, so net ≈ gross
Coverage & restrictions
0%of plans cover it
tier 1 · prior auth 0% · step therapy 0% · qty limit 0%
*No drug-level rebate is public — the estimate applies MedPAC's program-wide brand rebate range to this drug's gross price. Tracked here for 10 quarters since 2024.
NADAC price per unit
No NADAC pricing on file for this NDC — NADAC covers drugs dispensed by retail community pharmacies.
Supply fragility
Not scored — fragility is computed for NADAC-priced NDCs.
90-day shortage risk (model v2)
0.1%chance of a new FDA shortage posting for sulfamethoxazole and trimethoprim (oral solid) in the next 90 days
OAI inspection at a producing facility (24 months) · sole-source market
For scale: the typical drug’s chance is about 0.1% — this one is in ordinary territory.
Backtested statistical model over the whole market, not this package alone. Model details →
Regulatory
- Application
- ANDA090624
- TE code
- AB
- Approval date
- Feb 16, 2010
- Patents / exclusivity
- None on file
Shortage history
No FDA shortage reports for this drug or its presentations.
Recalls (this NDC)
No enforcement reports list this package NDC.
Manufacturers of Sulfamethoxazole and Trimethoprim (Tablet)
| Labeler | Strength | First seen | Last seen |
|---|---|---|---|
| A-S Medication Solutions | SULFAMETHOXAZOLE 800 mg/1; TRIMETHOPRIM 160 mg/1 | Jul 15, 2026 | Sep 3, 2026 |
| Advanced Rx Pharmacy of Tennessee, LLC | TRIMETHOPRIM 160 mg/1; SULFAMETHOXAZOLE 800 mg/1 | Aug 26, 2026 | Sep 3, 2026 |
| Northwind Health Company, LLC | SULFAMETHOXAZOLE 800 mg/1; TRIMETHOPRIM 160 mg/1 | Jul 15, 2026 | Sep 3, 2026 |
| NuCare Pharmaceuticals,Inc. | SULFAMETHOXAZOLE 800 mg/1; TRIMETHOPRIM 160 mg/1 | Jul 15, 2026 | Sep 3, 2026 |
| PD-Rx Pharmaceuticals, Inc. | SULFAMETHOXAZOLE 800 mg/1; TRIMETHOPRIM 160 mg/1 | Jul 15, 2026 | Sep 3, 2026 |
| Proficient Rx LP | SULFAMETHOXAZOLE 800 mg/1; TRIMETHOPRIM 160 mg/1 | Jul 15, 2026 | Sep 3, 2026 |
| Remedyrepack Inc. | SULFAMETHOXAZOLE 800 mg/1; TRIMETHOPRIM 160 mg/1 | Jul 15, 2026 | Sep 3, 2026 |
| Advanced Rx Pharmacy of Tennessee, LLC | SULFAMETHOXAZOLE 800 mg/1; TRIMETHOPRIM 160 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| American Health Packaging | SULFAMETHOXAZOLE 800 mg/1; TRIMETHOPRIM 160 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Amneal Pharmaceuticals LLC | SULFAMETHOXAZOLE 400 mg/1; TRIMETHOPRIM 80 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Amneal Pharmaceuticals LLC | SULFAMETHOXAZOLE 800 mg/1; TRIMETHOPRIM 160 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Amneal Pharmaceuticals of New York LLC | SULFAMETHOXAZOLE 400 mg/1; TRIMETHOPRIM 80 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Amneal Pharmaceuticals of New York LLC | SULFAMETHOXAZOLE 800 mg/1; TRIMETHOPRIM 160 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Asclemed USA, Inc. | SULFAMETHOXAZOLE 800 mg/1; TRIMETHOPRIM 160 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Aurobindo Pharma Limited | SULFAMETHOXAZOLE 400 mg/1; TRIMETHOPRIM 80 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| AvKARE | SULFAMETHOXAZOLE 400 mg/1; TRIMETHOPRIM 80 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| AvKARE | SULFAMETHOXAZOLE 800 mg/1; TRIMETHOPRIM 160 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| AvPAK | SULFAMETHOXAZOLE 400 mg/1; TRIMETHOPRIM 80 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Chartwell RX, LLC | SULFAMETHOXAZOLE 800 mg/1; TRIMETHOPRIM 160 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Chartwell RX, LLC | SULFAMETHOXAZOLE 400 mg/1; TRIMETHOPRIM 80 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Coupler LLC | SULFAMETHOXAZOLE 800 mg/1; TRIMETHOPRIM 160 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Cronus Pharma LLC | SULFAMETHOXAZOLE 400 mg/1; TRIMETHOPRIM 80 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Cronus Pharma LLC | SULFAMETHOXAZOLE 800 mg/1; TRIMETHOPRIM 160 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Denton Pharma, Inc. DBA Northwind Pharmaceuticals | SULFAMETHOXAZOLE 800 mg/1; TRIMETHOPRIM 160 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Golden State Medical Supply, Inc. | SULFAMETHOXAZOLE 800 mg/1; TRIMETHOPRIM 160 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Major Pharmaceuticals | SULFAMETHOXAZOLE 800 mg/1; TRIMETHOPRIM 160 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| NCS HealthCare of KY, LLC dba Vangard Labs | SULFAMETHOXAZOLE 800 mg/1; TRIMETHOPRIM 160 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| NuCare Pharmaceuticals,Inc. | SULFAMETHOXAZOLE 400 mg/1; TRIMETHOPRIM 80 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Pharmasource Meds, LLC | SULFAMETHOXAZOLE 800 mg/1; TRIMETHOPRIM 160 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Preferred Pharmaceuticals Inc. | SULFAMETHOXAZOLE 800 mg/1; TRIMETHOPRIM 160 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| QPharma, Inc. | SULFAMETHOXAZOLE 800 mg/1; TRIMETHOPRIM 160 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Quality Care Products LLC | SULFAMETHOXAZOLE 800 mg/1; TRIMETHOPRIM 160 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Remedyrepack Inc. | SULFAMETHOXAZOLE 400 mg/1; TRIMETHOPRIM 80 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Rising Pharma Holdings, Inc. | SULFAMETHOXAZOLE 800 mg/1; TRIMETHOPRIM 160 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Rising Pharma Holdings, Inc. | SULFAMETHOXAZOLE 400 mg/1; TRIMETHOPRIM 80 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Sportpharm LLC | SULFAMETHOXAZOLE 800 mg/1; TRIMETHOPRIM 160 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| St. Mary's Medical Park Pharmacy | SULFAMETHOXAZOLE 800 mg/1; TRIMETHOPRIM 160 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Sun Pharmaceutical Industries, Inc | SULFAMETHOXAZOLE 400 mg/1; TRIMETHOPRIM 80 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Sun Pharmaceutical Industries, Inc | SULFAMETHOXAZOLE 800 mg/1; TRIMETHOPRIM 160 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Sun Pharmaceutical Industries, Inc. | SULFAMETHOXAZOLE 800 mg/1; TRIMETHOPRIM 160 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
Roster from daily NDC Directory diffs — first/last seen dates start July 2026.
Cite this page
DrugDashboards, "Sulfamethoxazole and Trimethoprim — NDC 70518-3454-03," retrieved September 3, 2026, https://drugdashboards.com/drug/70518345403.
Free to cite with attribution — see how the data is put together.