The short version
16 companies supply this market — deep enough that no single failure threatens the supply.
The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.
isosorbide dinitrate · ISOSORBIDE DINITRATE 10 mg/1 · Tablet · Oral · Remedyrepack Inc.
NDC 70518-4405-00 · 30 TABLET in 1 BLISTER PACK · ANDA · View full market →
16 companies supply this market — deep enough that no single failure threatens the supply.
The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.
Matched to CMS's representative package for this drug (NDC 00143-1771-01) — same generic, strength, and dosage form. CMS prices one NDC per drug concept, not every package.
Negotiated 30-day point-of-sale unit prices and formulary terms aggregated across every unsuppressed Part D and MA-PD plan for the quarter shown. Point of sale means gross of confidential rebates. CMS publishes one representative NDC per drug concept (RxCUI) rather than every package, so these figures come from CMS's representative package for the same drug — matched on generic name, strength, and dosage form. Estimated from MedPAC's program-wide rebate aggregates (June 2023: DIR = 29% of gross Part D spending; brand rebates ≈ 25–40% of gross, generics minimal). Actual rebates are confidential and vary widely by drug — this is a range, not a fact about this drug.
Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.
*No drug-level rebate is public — the estimate applies MedPAC's program-wide brand rebate range to this drug's gross price. Tracked here for 10 quarters since 2024.
No NADAC pricing on file for this NDC — NADAC covers drugs dispensed by retail community pharmacies.
Not scored — fragility is computed for NADAC-priced NDCs.
sole-source market
For scale: the typical drug’s chance is about 0.1% — this one is in ordinary territory.
Backtested statistical model over the whole market, not this package alone. Model details →
No FDA shortage reports for this drug or its presentations.
No enforcement reports list this package NDC.
| Labeler | Strength | First seen | Last seen |
|---|---|---|---|
| Par Health USA, LLC | ISOSORBIDE DINITRATE 40 mg/1 | Aug 6, 2026 | Sep 3, 2026 |
| Advagen Pharma Ltd | ISOSORBIDE DINITRATE 40 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Advagen Pharma Ltd | ISOSORBIDE DINITRATE 20 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Advagen Pharma Ltd | ISOSORBIDE DINITRATE 30 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Advagen Pharma Ltd | ISOSORBIDE DINITRATE 5 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Advagen Pharma Ltd | ISOSORBIDE DINITRATE 10 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| American Health Packaging | ISOSORBIDE DINITRATE 20 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| American Health Packaging | ISOSORBIDE DINITRATE 10 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| AvPAK | ISOSORBIDE DINITRATE 5 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| AvPAK | ISOSORBIDE DINITRATE 20 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| AvPAK | ISOSORBIDE DINITRATE 10 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| BluePoint Laboratories | ISOSORBIDE DINITRATE 5 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| BluePoint Laboratories | ISOSORBIDE DINITRATE 20 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| BluePoint Laboratories | ISOSORBIDE DINITRATE 30 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| BluePoint Laboratories | ISOSORBIDE DINITRATE 10 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Bryant Ranch Prepack | ISOSORBIDE DINITRATE 40 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Cardinal Health 107, LLC | ISOSORBIDE DINITRATE 10 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Cardinal Health 107, LLC | ISOSORBIDE DINITRATE 20 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Golden State Medical Supply, Inc. | ISOSORBIDE DINITRATE 20 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Golden State Medical Supply, Inc. | ISOSORBIDE DINITRATE 10 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Golden State Medical Supply, Inc. | ISOSORBIDE DINITRATE 5 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Hikma Pharmaceuticals USA Inc. | ISOSORBIDE DINITRATE 5 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Hikma Pharmaceuticals USA Inc. | ISOSORBIDE DINITRATE 10 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Hikma Pharmaceuticals USA Inc. | ISOSORBIDE DINITRATE 20 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Major Pharmaceuticals | ISOSORBIDE DINITRATE 10 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Major Pharmaceuticals | ISOSORBIDE DINITRATE 20 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| NCS HealthCare of KY, LLC dba Vangard Labs | ISOSORBIDE DINITRATE 10 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| NCS HealthCare of KY, LLC dba Vangard Labs | ISOSORBIDE DINITRATE 20 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| NCS HealthCare of KY, LLC dba Vangard Labs | ISOSORBIDE DINITRATE 30 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Northstar Rx LLC | ISOSORBIDE DINITRATE 5 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Northstar Rx LLC | ISOSORBIDE DINITRATE 20 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Northstar Rx LLC | ISOSORBIDE DINITRATE 10 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Northstar Rx LLC | ISOSORBIDE DINITRATE 30 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Oceanside Pharmaceuticals | ISOSORBIDE DINITRATE 40 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Oceanside Pharmaceuticals | ISOSORBIDE DINITRATE 5 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Proficient Rx LP | ISOSORBIDE DINITRATE 20 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Proficient Rx LP | ISOSORBIDE DINITRATE 10 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Remedyrepack Inc. | ISOSORBIDE DINITRATE 10 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Sandoz Inc. | ISOSORBIDE DINITRATE 5 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Sandoz Inc. | ISOSORBIDE DINITRATE 10 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
Roster from daily NDC Directory diffs — first/last seen dates start July 2026.
DrugDashboards, "Isosorbide Dinitrate — NDC 70518-4405-00," retrieved September 3, 2026, https://drugdashboards.com/drug/70518440500.
Free to cite with attribution — see how the data is put together.