The short version
Just 3 companies supply this market — thin enough that a single exit would be felt immediately.
The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.
Carbidopa and Levodopa
Carbidopa and Levodopa · CARBIDOPA 36.25 mg/1; LEVODOPA 145 mg/1 · Capsule, Extended Release · Oral · Remedyrepack Inc.
NDC 70518-4630-00 · 50 POUCH in 1 BOX / 1 CAPSULE, EXTENDED RELEASE in 1 POUCH · NDA AUTHORIZED GENERIC · View full market →
Medicare Part D
All Part D pricing →Matched to CMS's representative package for this drug (NDC 70710-2140-01) — same generic, strength, and dosage form. CMS prices one NDC per drug concept, not every package.
ⓘ How this was built
Data sources
- CMS quarterly Prescription Drug Plan Formulary & Pricing files (SPUF)
Method
Negotiated 30-day point-of-sale unit prices and formulary terms aggregated across every unsuppressed Part D and MA-PD plan for the quarter shown. Point of sale means gross of confidential rebates. CMS publishes one representative NDC per drug concept (RxCUI) rather than every package, so these figures come from CMS's representative package for the same drug — matched on generic name, strength, and dosage form. Estimated from MedPAC's program-wide rebate aggregates (June 2023: DIR = 29% of gross Part D spending; brand rebates ≈ 25–40% of gross, generics minimal). Actual rebates are confidential and vary widely by drug — this is a range, not a fact about this drug.
Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.
Plans pay at point of saleⓘ
$3.65per unit
middle half $2.91–$3.74 · 104 plans · Apr 1, 2026
Est. net of rebatesⓘ
≈ $3.65
generic — rebates are minimal, so net ≈ gross
Coverage & restrictions
2%of plans cover it
tier 4 · prior auth 0% · step therapy 52% · qty limit 53%
*No drug-level rebate is public — the estimate applies MedPAC's program-wide brand rebate range to this drug's gross price. Tracked here for 2 quarters since 2024.
NADAC price per unit
No NADAC pricing on file for this NDC — NADAC covers drugs dispensed by retail community pharmacies.
Supply fragility
Not scored — fragility is computed for NADAC-priced NDCs.
90-day shortage risk (model v2)
0.1%chance of a new FDA shortage posting for carbidopa and levodopa (oral solid) in the next 90 days
OAI inspection at a producing facility (24 months) · sole-source market
For scale: the typical drug’s chance is about 0.1% — this one is in ordinary territory.
Backtested statistical model over the whole market, not this package alone. Model details →
Regulatory
- Application
- NDA203312
- TE code
- —
- Approval date
- Jan 7, 2015
- Patents / exclusivity
- 32 patents, 0 exclusivities
| Type | Number / code | Expires |
|---|---|---|
| patent | 9089607 | Dec 26, 2028 |
| patent | 9089607 | Dec 26, 2028 |
| patent | 8377474 | Dec 26, 2028 |
| patent | 8377474 | Dec 26, 2028 |
| patent | 8377474 | Dec 26, 2028 |
| patent | 8377474 | Dec 26, 2028 |
| patent | 8454998 | Dec 26, 2028 |
| patent | 8454998 | Dec 26, 2028 |
| patent | 8454998 | Dec 26, 2028 |
| patent | 8454998 | Dec 26, 2028 |
| patent | 8557283 | Dec 26, 2028 |
| patent | 9901640 | Dec 26, 2028 |
Shortage history
No FDA shortage reports for this drug or its presentations.
Recalls (this NDC)
No enforcement reports list this package NDC.
Manufacturers of Carbidopa and Levodopa (Capsule, Extended Release)
| Labeler | Strength | First seen | Last seen |
|---|---|---|---|
| Amneal Pharmaceuticals LLC | LEVODOPA 95 mg/1; CARBIDOPA HYDRATE 23.75 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| Amneal Pharmaceuticals LLC | CARBIDOPA HYDRATE 35 mg/1; LEVODOPA 140 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Amneal Pharmaceuticals LLC | CARBIDOPA HYDRATE 52.5 mg/1; LEVODOPA 210 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Amneal Pharmaceuticals LLC | CARBIDOPA HYDRATE 70 mg/1; LEVODOPA 280 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Amneal Pharmaceuticals LLC | CARBIDOPA HYDRATE 87.5 mg/1; LEVODOPA 350 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Amneal Pharmaceuticals LLC | LEVODOPA 145 mg/1; CARBIDOPA HYDRATE 36.25 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| Amneal Pharmaceuticals LLC | LEVODOPA 195 mg/1; CARBIDOPA HYDRATE 48.75 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| Amneal Pharmaceuticals LLC | LEVODOPA 245 mg/1; CARBIDOPA HYDRATE 61.25 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| Remedyrepack Inc. | CARBIDOPA 48.75 mg/1; LEVODOPA 195 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Remedyrepack Inc. | CARBIDOPA 23.75 mg/1; LEVODOPA 95 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Remedyrepack Inc. | CARBIDOPA 36.25 mg/1; LEVODOPA 145 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Remedyrepack Inc. | CARBIDOPA 61.25 mg/1; LEVODOPA 245 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Zydus Pharmaceuticals USA Inc. | CARBIDOPA 61.25 mg/1; LEVODOPA 245 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Zydus Pharmaceuticals USA Inc. | CARBIDOPA 48.75 mg/1; LEVODOPA 195 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Zydus Pharmaceuticals USA Inc. | CARBIDOPA 23.75 mg/1; LEVODOPA 95 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Zydus Pharmaceuticals USA Inc. | CARBIDOPA 36.25 mg/1; LEVODOPA 145 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Amneal Pharmaceuticals LLC | LEVODOPA 48.75 mg/1; CARBIDOPA HYDRATE 195 mg/1 | Jul 22, 2026 | Aug 19, 2026 |
| Amneal Pharmaceuticals LLC | LEVODOPA 61.25 mg/1; CARBIDOPA HYDRATE 245 mg/1 | Jul 22, 2026 | Aug 19, 2026 |
| Amneal Pharmaceuticals LLC | LEVODOPA 23.75 mg/1; CARBIDOPA HYDRATE 95 mg/1 | Jul 22, 2026 | Aug 19, 2026 |
| Amneal Pharmaceuticals LLC | LEVODOPA 36.25 mg/1; CARBIDOPA HYDRATE 145 mg/1 | Jul 22, 2026 | Aug 19, 2026 |
| Amneal Pharmaceuticals LLC | CARBIDOPA HYDRATE 23.75 mg/1; LEVODOPA 95 mg/1 | Jul 15, 2026 | Jul 15, 2026 |
| Amneal Pharmaceuticals LLC | CARBIDOPA HYDRATE 61.25 mg/1; LEVODOPA 245 mg/1 | Jul 15, 2026 | Jul 15, 2026 |
| Amneal Pharmaceuticals LLC | CARBIDOPA HYDRATE 48.75 mg/1; LEVODOPA 195 mg/1 | Jul 15, 2026 | Jul 15, 2026 |
| Amneal Pharmaceuticals LLC | CARBIDOPA HYDRATE 36.25 mg/1; LEVODOPA 145 mg/1 | Jul 15, 2026 | Jul 15, 2026 |
Roster from daily NDC Directory diffs — first/last seen dates start July 2026.
Cite this page
DrugDashboards, "Carbidopa and Levodopa — NDC 70518-4630-00," retrieved September 3, 2026, https://drugdashboards.com/drug/70518463000.
Free to cite with attribution — see how the data is put together.