DrugDashboards

Pain Reliever PM

Acetaminophen, Diphenhydramine HCl · ACETAMINOPHEN 500 mg/1; DIPHENHYDRAMINE HYDROCHLORIDE 25 mg/1 · Tablet, Coated · Oral · Strategic Sourcing Services LLC

NDC 70677-1149-01 · 1 BOTTLE, PLASTIC in 1 BOX / 50 TABLET, COATED in 1 BOTTLE, PLASTIC · OTC MONOGRAPH DRUG · View full market →

The short version

23 companies supply this market — deep enough that no single failure threatens the supply. The price has held steady around $0.0444 per unit over the past year. Put together: this looks like a healthy supply — the boring kind, which is exactly what you want.

The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.

Medicare Part D

Medicare Part D does not cover over-the-counter drugs — by law it pays only for products requiring a prescription.

How Part D pricing works →

NADAC price per unit

$0$0.02$0.04$0.06Dec 2023Sep 2026$0.0444
34 price points · per EASource: CMS NADAC

Estimated fill cost

#30 count
$1.33
#90 count
$4.00

Estimates: latest NADAC unit price × quantity. Pharmacy acquisition cost only — excludes dispensing fees, markup, and insurance terms.

Medicaid spend (2025)

$131
11 prescriptions paid by Medicaid nationally · all Medicaid spend →

Supply fragility

0● Low risk

Nothing here is signaling trouble: several manufacturers, no current shortage, no recent serious recalls, stable pricing. In drug supply, boring is the good outcome.

The score counts pressure that is already visible — fewer makers, shortages, recalls, falling prices. 0 means none of it; 100 means all of it at once. Recomputed daily · as of Sep 3, 2026

90-day shortage risk (model v2)

0.1%chance of a new FDA shortage posting for acetaminophen, diphenhydramine hcl (oral solid) in the next 90 days

sole-source market

For scale: the typical drug’s chance is about 0.1% — this one is in ordinary territory.

Backtested statistical model over the whole market, not this package alone. Model details →

Is this a "specialty" drug?

There's no legal definition — it meets 1 of 6 public criteria. Why that matters →

  • Part D specialty tier
  • Costs ≥ $950/fill
  • Biologic (BLA)
  • Injectable / infused
  • Orphan-drug exclusivity
  • REMS program · Opioid Analgesic REMS Shared System REMS

Regulatory

Application
M013
TE code
—
Approval date
—
Patents / exclusivity
None on file

Shortage history

No FDA shortage reports for this drug or its presentations.

Recalls (this NDC)

No enforcement reports list this package NDC.

Manufacturers of Acetaminophen, Diphenhydramine HCl (Tablet, Coated)

LabelerStrengthFirst seenLast seen
BJWC (Berkley & Jensen / BJ's)ACETAMINOPHEN 500 mg/1; DIPHENHYDRAMINE HYDROCHLORIDE 25 mg/1Jul 15, 2026Sep 2, 2026
Chain Drug Marketing Association IncACETAMINOPHEN 500 mg/1; DIPHENHYDRAMINE HYDROCHLORIDE 25 mg/1Jul 15, 2026Sep 2, 2026
Chain Drug Marketing Association, Inc.ACETAMINOPHEN 500 mg/1; DIPHENHYDRAMINE HYDROCHLORIDE 25 mg/1Jul 15, 2026Sep 2, 2026
Costco Wholesale CorporationACETAMINOPHEN 500 mg/1; DIPHENHYDRAMINE HYDROCHLORIDE 25 mg/1Jul 15, 2026Sep 2, 2026
Cvs PharmacyACETAMINOPHEN 500 mg/1; DIPHENHYDRAMINE HYDROCHLORIDE 25 mg/1Jul 15, 2026Sep 2, 2026
Cvs Pharmacy, IncACETAMINOPHEN 500 mg/1; DIPHENHYDRAMINE HYDROCHLORIDE 25 mg/1Jul 15, 2026Sep 2, 2026
EQUATE (Wal-Mart Stores, Inc.) (see also WAL-MART INC)ACETAMINOPHEN 500 mg/1; DIPHENHYDRAMINE HYDROCHLORIDE 25 mg/1Jul 15, 2026Sep 2, 2026
Family Dollar (FAMILY WELLNESS)ACETAMINOPHEN 500 mg/1; DIPHENHYDRAMINE HYDROCHLORIDE 25 mg/1Jul 15, 2026Sep 2, 2026
Foodhold U.s.a., LlcACETAMINOPHEN 500 mg/1; DIPHENHYDRAMINE HYDROCHLORIDE 25 mg/1Jul 15, 2026Sep 2, 2026
H E BACETAMINOPHEN 500 mg/1; DIPHENHYDRAMINE HYDROCHLORIDE 25 mg/1Jul 15, 2026Sep 2, 2026
L.N.K. International, Inc.ACETAMINOPHEN 500 mg/1; DIPHENHYDRAMINE HYDROCHLORIDE 25 mg/1Jul 15, 2026Sep 2, 2026
QUALITY CHOICE (Chain Drug Marketing Association)ACETAMINOPHEN 500 mg/1; DIPHENHYDRAMINE HYDROCHLORIDE 25 mg/1Jul 15, 2026Sep 2, 2026
Sam's West IncACETAMINOPHEN 500 mg/1; DIPHENHYDRAMINE HYDROCHLORIDE 25 mg/1Jul 15, 2026Sep 2, 2026
TARGET CorporationACETAMINOPHEN 500 mg/1; DIPHENHYDRAMINE HYDROCHLORIDE 25 mg/1Jul 15, 2026Sep 2, 2026
TOP CARE (Topco Associates LLC)ACETAMINOPHEN 500 mg/1; DIPHENHYDRAMINE HYDROCHLORIDE 25 mg/1Jul 15, 2026Sep 2, 2026
Topco Associates, LLCACETAMINOPHEN 500 mg/1; DIPHENHYDRAMINE HYDROCHLORIDE 25 mg/1Jul 15, 2026Sep 2, 2026
United Natural Foods, Inc. dba UNFIACETAMINOPHEN 500 mg/1; DIPHENHYDRAMINE HYDROCHLORIDE 25 mg/1Jul 15, 2026Sep 2, 2026
Walgreen CompanyACETAMINOPHEN 500 mg/1; DIPHENHYDRAMINE HYDROCHLORIDE 25 mg/1Jul 15, 2026Sep 2, 2026
Walmart Inc.ACETAMINOPHEN 500 mg/1; DIPHENHYDRAMINE HYDROCHLORIDE 25 mg/1Jul 15, 2026Sep 2, 2026
WR Group, Inc.ACETAMINOPHEN 500 mg/1; DIPHENHYDRAMINE HYDROCHLORIDE 25 mg/1Jul 15, 2026Sep 2, 2026
Strategic Sourcing Services LLCACETAMINOPHEN 500 mg/1; DIPHENHYDRAMINE HYDROCHLORIDE 25 mg/1Jul 15, 2026Aug 28, 2026
WalgreensACETAMINOPHEN 500 mg/1; DIPHENHYDRAMINE HYDROCHLORIDE 25 mg/1Jul 15, 2026Aug 28, 2026
Big LotsACETAMINOPHEN 500 mg/1; DIPHENHYDRAMINE HYDROCHLORIDE 25 mg/1Jul 15, 2026Aug 19, 2026

Roster from daily NDC Directory diffs — first/last seen dates start July 2026.

Cite this page

DrugDashboards, "Pain Reliever PM — NDC 70677-1149-01," retrieved September 3, 2026, https://drugdashboards.com/drug/70677114901.

Free to cite with attribution — see how the data is put together.