The short version
18 companies supply this market — deep enough that no single failure threatens the supply.
The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.
Theophylline · THEOPHYLLINE ANHYDROUS 200 mg/1 · Tablet, Extended Release · Oral · Brandywine Pharmaceuticals, LLC
NDC 71321-0501-10 · 100 TABLET, EXTENDED RELEASE in 1 BOTTLE · ANDA · View full market →
18 companies supply this market — deep enough that no single failure threatens the supply.
The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.
The same NDC has different prices depending on who is paying. Units differ between rungs — compare within a rung over time, not rung against rung, unless the units match.
Each rung is the newest figure for this NDC from one federal price system, shown with its own unit. Part D is matched by drug name because CMS publishes no NDCs there; it is gross spending, before confidential rebates.
Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.
Negotiated 30-day point-of-sale unit prices and formulary terms aggregated across every unsuppressed Part D and MA-PD plan for the quarter shown. Point of sale means gross of confidential rebates. CMS publishes one representative NDC per drug concept (RxCUI) rather than every package, so these figures come from CMS's representative package for the same drug — matched on generic name, strength, and dosage form. Estimated from MedPAC's program-wide rebate aggregates (June 2023: DIR = 29% of gross Part D spending; brand rebates ≈ 25–40% of gross, generics minimal). Actual rebates are confidential and vary widely by drug — this is a range, not a fact about this drug.
Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.
*No drug-level rebate is public — the estimate applies MedPAC's program-wide brand rebate range to this drug's gross price. Tracked here for 2 quarters since 2024.
No NADAC pricing on file for this NDC — NADAC covers drugs dispensed by retail community pharmacies.
Manufacturer list price as filed — not what pharmacies actually pay after discounts.
Not scored — fragility is computed for NADAC-priced NDCs.
sole-source market
For scale: the typical drug’s chance is about 0.1% — this one is in ordinary territory.
Backtested statistical model over the whole market, not this package alone. Model details →
Establishments this product's FDA label declares, located via FDA registration data. How we built this →
No FDA shortage reports for this drug or its presentations.
No enforcement reports list this package NDC.
| Labeler | Strength | First seen | Last seen |
|---|---|---|---|
| Ajanta Pharma USA Inc. | THEOPHYLLINE ANHYDROUS 450 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Ajanta Pharma USA Inc. | THEOPHYLLINE ANHYDROUS 300 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Alembic Pharmaceuticals Inc. | THEOPHYLLINE ANHYDROUS 300 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Alembic Pharmaceuticals Inc. | THEOPHYLLINE ANHYDROUS 450 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Alembic Pharmaceuticals Limited | THEOPHYLLINE ANHYDROUS 450 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Alembic Pharmaceuticals Limited | THEOPHYLLINE ANHYDROUS 300 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Amneal Pharmaceuticals NY LLC | THEOPHYLLINE ANHYDROUS 450 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Amneal Pharmaceuticals NY LLC | THEOPHYLLINE ANHYDROUS 300 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| AvKARE | THEOPHYLLINE ANHYDROUS 300 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Bionpharma Inc., | THEOPHYLLINE ANHYDROUS 300 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Camber Pharmaceuticals, Inc. | THEOPHYLLINE ANHYDROUS 450 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Camber Pharmaceuticals, Inc. | THEOPHYLLINE ANHYDROUS 300 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Chartwell RX, LLC | THEOPHYLLINE ANHYDROUS 300 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Glenmark Pharmaceuticals Inc., USA | THEOPHYLLINE ANHYDROUS 400 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Glenmark Pharmaceuticals Inc., USA | THEOPHYLLINE ANHYDROUS 600 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Glenmark Pharmaceuticals Inc., USA | THEOPHYLLINE ANHYDROUS 450 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Glenmark Pharmaceuticals Inc., USA | THEOPHYLLINE ANHYDROUS 300 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Golden State Medical Supply, Inc. | THEOPHYLLINE ANHYDROUS 600 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Golden State Medical Supply, Inc. | THEOPHYLLINE ANHYDROUS 400 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Harman Finochem Limited | THEOPHYLLINE ANHYDROUS 300 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Harman Finochem Limited | THEOPHYLLINE ANHYDROUS 450 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc. | THEOPHYLLINE ANHYDROUS 300 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc. | THEOPHYLLINE ANHYDROUS 450 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Leading Pharma, LLC | THEOPHYLLINE 300 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Leading Pharma, LLC | THEOPHYLLINE 450 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| PD-Rx Pharmaceuticals, Inc. | THEOPHYLLINE ANHYDROUS 450 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| PD-Rx Pharmaceuticals, Inc. | THEOPHYLLINE ANHYDROUS 300 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Strides Pharma Science Limited | THEOPHYLLINE ANHYDROUS 450 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Strides Pharma Science Limited | THEOPHYLLINE ANHYDROUS 300 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Teva Pharmaceuticals, Inc. | THEOPHYLLINE 300 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Teva Pharmaceuticals, Inc. | THEOPHYLLINE 450 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Viona Pharmaceuticals Inc | THEOPHYLLINE ANHYDROUS 450 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Viona Pharmaceuticals Inc | THEOPHYLLINE ANHYDROUS 300 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Zydus Lifesciences Limited | THEOPHYLLINE ANHYDROUS 300 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Zydus Lifesciences Limited | THEOPHYLLINE ANHYDROUS 450 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Brandywine Pharmaceuticals, LLC | THEOPHYLLINE ANHYDROUS 300 mg/1 | Jul 15, 2026 | Jul 29, 2026 |
| Brandywine Pharmaceuticals, LLC | THEOPHYLLINE ANHYDROUS 200 mg/1 | Jul 15, 2026 | Jul 29, 2026 |
| Brandywine Pharmaceuticals, LLC | THEOPHYLLINE ANHYDROUS 100 mg/1 | Jul 15, 2026 | Jul 29, 2026 |
Roster from daily NDC Directory diffs — first/last seen dates start July 2026.
DrugDashboards, "Theophylline — NDC 71321-0501-10," retrieved September 3, 2026, https://drugdashboards.com/drug/71321050110.
Free to cite with attribution — see how the data is put together.