DrugDashboards

Hydrocodone Bitartrate and Acetaminophen

Hydrocodone Bitartrate and Acetaminophen · HYDROCODONE BITARTRATE 7.5 mg/15mL; ACETAMINOPHEN 325 mg/15mL · Solution · Oral · Eywa Pharma Inc

NDC 71930-0027-43 · 473 mL in 1 BOTTLE · ANDA · View full market →

The short version

7 companies supply this market — a reasonable cushion if one runs into trouble. The price has held steady around $0.2450 per mL over the past year. Put together: this looks like a healthy supply — the boring kind, which is exactly what you want.

The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.

One drug, every price

The same NDC has different prices depending on who is paying. Units differ between rungs — compare within a rung over time, not rung against rung, unless the units match.

ⓘ How this was built
Data sources
  • CMS NADAC (pharmacy acquisition, weekly)
  • CMS Part B ASP quarterly payment limits
  • CMS Maximum Fair Prices (IRA negotiated, NDC-level)
  • Medicare Part D Spending by Drug (data.cms.gov, name-matched)
  • VA FSS / Big4 federal contract prices (va.gov, twice monthly)
  • ACA Federal Upper Limits + weighted AMP (data.medicaid.gov, monthly)
  • California SB-17 WAC filings (list price, per package)
Method

Each rung is the newest figure for this NDC from one federal price system, shown with its own unit. Part D is matched by drug name because CMS publishes no NDCs there; it is gross spending, before confidential rebates.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

  • Pharmacies pay (NADAC)$0.2450per MLinvoice-surveyed acquisition cost · Aug 19, 2026
  • Medicaid generic ceiling (FUL)$0.2450per MLweighted avg manufacturer price $0.1195 · Aug 1, 2026100% of what pharmacies pay — higher than 10% of drugs with this benchmark

Medicare Part D

All Part D pricing →

Matched to CMS's representative package for this drug (NDC 64950-0343-16) — same generic, strength, and dosage form. CMS prices one NDC per drug concept, not every package.

ⓘ How this was built
Data sources
  • CMS quarterly Prescription Drug Plan Formulary & Pricing files (SPUF)
Method

Negotiated 30-day point-of-sale unit prices and formulary terms aggregated across every unsuppressed Part D and MA-PD plan for the quarter shown. Point of sale means gross of confidential rebates. CMS publishes one representative NDC per drug concept (RxCUI) rather than every package, so these figures come from CMS's representative package for the same drug — matched on generic name, strength, and dosage form. Estimated from MedPAC's program-wide rebate aggregates (June 2023: DIR = 29% of gross Part D spending; brand rebates ≈ 25–40% of gross, generics minimal). Actual rebates are confidential and vary widely by drug — this is a range, not a fact about this drug.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

Plans pay at point of sale
$0.2771per unit
middle half $0.2082$0.3498 · 5,189 plans · Apr 1, 2026
Est. net of rebates
≈ $0.2771
generic — rebates are minimal, so net ≈ gross
Coverage & restrictions
94%of plans cover it
tier 4 · prior auth 0% · step therapy 0% · qty limit 95%

*No drug-level rebate is public — the estimate applies MedPAC's program-wide brand rebate range to this drug's gross price. Tracked here for 10 quarters since 2024.

NADAC price per unit

$0$0.2$0.4Jun 2019Sep 2026$0.245
81 price points · per ML · dashed = manufacturer avg (WAMP)Source: CMS NADAC

Estimated fill cost

WAC per package, as filed
$112.00
Reported to Texas DSHS · 2026 annual filing · Eywa Pharma Inc.

Manufacturer list price as filed — not what pharmacies actually pay after discounts.

Medicaid spend (2025)

$944,025
24,837 prescriptions paid by Medicaid nationally · all Medicaid spend →

Supply fragility

0Low risk

Nothing here is signaling trouble: several manufacturers, no current shortage, no recent serious recalls, stable pricing. In drug supply, boring is the good outcome.

The score counts pressure that is already visible — fewer makers, shortages, recalls, falling prices. 0 means none of it; 100 means all of it at once. Recomputed daily · as of Sep 3, 2026

90-day shortage risk (model v2)

0.1%chance of a new FDA shortage posting for hydrocodone bitartrate and acetaminophen (other) in the next 90 days

price up 13% YoY · sole-source market

For scale: the typical drug’s chance is about 0.1% — this one is in ordinary territory.

Backtested statistical model over the whole market, not this package alone. Model details →

Is this a "specialty" drug?

There's no legal definition — it meets 1 of 6 public criteria. Why that matters →

  • Part D specialty tier
  • Costs ≥ $950/fill
  • Biologic (BLA)
  • Injectable / infused
  • Orphan-drug exclusivity
  • REMS program · Opioid Analgesic REMS Shared System REMS

Regulatory

Application
ANDA211023
TE code
AA
Approval date
Mar 8, 2019
Patents / exclusivity
None on file

Shortage history

No FDA shortage reports for this drug or its presentations.

Recalls (this NDC)

No enforcement reports list this package NDC.

Manufacturers of Hydrocodone Bitartrate and Acetaminophen (Solution)

LabelerStrengthFirst seenLast seen
Genus Lifesciences Inc.HYDROCODONE BITARTRATE 7.5 mg/15mL; ACETAMINOPHEN 325 mg/15mLAug 26, 2026Sep 3, 2026
American Health PackagingHYDROCODONE BITARTRATE 7.5 mg/15mL; ACETAMINOPHEN 325 mg/15mLAug 26, 2026Sep 2, 2026
Cranbury Pharmaceuticals, LLCHYDROCODONE BITARTRATE 10 mg/15mL; ACETAMINOPHEN 300 mg/15mLAug 26, 2026Sep 2, 2026
Cranbury Pharmaceuticals, LLCHYDROCODONE BITARTRATE 7.5 mg/15mL; ACETAMINOPHEN 325 mg/15mLAug 26, 2026Sep 2, 2026
Eywa Pharma IncHYDROCODONE BITARTRATE 7.5 mg/15mL; ACETAMINOPHEN 325 mg/15mLAug 26, 2026Sep 2, 2026
PAI Holdings, LLC dba PAI PharmaHYDROCODONE BITARTRATE 2.5 mg/5mL; ACETAMINOPHEN 108 mg/5mLAug 26, 2026Sep 2, 2026
PAI Holdings, LLC dba PAI PharmaHYDROCODONE BITARTRATE 5 mg/10mL; ACETAMINOPHEN 217 mg/10mLAug 26, 2026Sep 2, 2026
PAI Holdings, LLC dba PAI PharmaHYDROCODONE BITARTRATE 7.5 mg/15mL; ACETAMINOPHEN 325 mg/15mLAug 26, 2026Sep 2, 2026
Redpharm drugHYDROCODONE BITARTRATE 7.5 mg/15mL; ACETAMINOPHEN 325 mg/15mLAug 26, 2026Sep 2, 2026
Redpharm DrugHYDROCODONE BITARTRATE 7.5 mg/15mL; ACETAMINOPHEN 325 mg/15mLAug 26, 2026Sep 2, 2026
Genus Lifesciences Inc.HYDROCODONE BITARTRATE 325 mg/15mL; ACETAMINOPHEN 7.5 mg/15mLJul 22, 2026Aug 21, 2026
American Health PackagingHYDROCODONE BITARTRATE 325 mg/15mL; ACETAMINOPHEN 7.5 mg/15mLJul 22, 2026Aug 19, 2026
Cranbury Pharmaceuticals, LLCHYDROCODONE BITARTRATE 300 mg/15mL; ACETAMINOPHEN 10 mg/15mLJul 22, 2026Aug 19, 2026
Cranbury Pharmaceuticals, LLCHYDROCODONE BITARTRATE 325 mg/15mL; ACETAMINOPHEN 7.5 mg/15mLJul 22, 2026Aug 19, 2026
Eywa Pharma IncHYDROCODONE BITARTRATE 325 mg/15mL; ACETAMINOPHEN 7.5 mg/15mLJul 22, 2026Aug 19, 2026
PAI Holdings, LLC dba PAI PharmaHYDROCODONE BITARTRATE 325 mg/15mL; ACETAMINOPHEN 7.5 mg/15mLJul 22, 2026Aug 19, 2026
PAI Holdings, LLC dba PAI PharmaHYDROCODONE BITARTRATE 108 mg/5mL; ACETAMINOPHEN 2.5 mg/5mLJul 22, 2026Aug 19, 2026
PAI Holdings, LLC dba PAI PharmaHYDROCODONE BITARTRATE 217 mg/10mL; ACETAMINOPHEN 5 mg/10mLJul 22, 2026Aug 19, 2026
Redpharm drugHYDROCODONE BITARTRATE 325 mg/15mL; ACETAMINOPHEN 7.5 mg/15mLJul 22, 2026Aug 19, 2026
Redpharm DrugHYDROCODONE BITARTRATE 325 mg/15mL; ACETAMINOPHEN 7.5 mg/15mLJul 22, 2026Aug 19, 2026
Genus Lifesciences Inc.ACETAMINOPHEN 325 mg/15mL; HYDROCODONE BITARTRATE 7.5 mg/15mLJul 15, 2026Jul 19, 2026
American Health PackagingACETAMINOPHEN 325 mg/15mL; HYDROCODONE BITARTRATE 7.5 mg/15mLJul 15, 2026Jul 15, 2026
Cranbury Pharmaceuticals, LLCACETAMINOPHEN 325 mg/15mL; HYDROCODONE BITARTRATE 7.5 mg/15mLJul 15, 2026Jul 15, 2026
Cranbury Pharmaceuticals, LLCACETAMINOPHEN 300 mg/15mL; HYDROCODONE BITARTRATE 10 mg/15mLJul 15, 2026Jul 15, 2026
Eywa Pharma IncACETAMINOPHEN 325 mg/15mL; HYDROCODONE BITARTRATE 7.5 mg/15mLJul 15, 2026Jul 15, 2026
PAI Holdings, LLC dba PAI PharmaACETAMINOPHEN 217 mg/10mL; HYDROCODONE BITARTRATE 5 mg/10mLJul 15, 2026Jul 15, 2026
PAI Holdings, LLC dba PAI PharmaACETAMINOPHEN 325 mg/15mL; HYDROCODONE BITARTRATE 7.5 mg/15mLJul 15, 2026Jul 15, 2026
PAI Holdings, LLC dba PAI PharmaACETAMINOPHEN 108 mg/5mL; HYDROCODONE BITARTRATE 2.5 mg/5mLJul 15, 2026Jul 15, 2026
Redpharm drugACETAMINOPHEN 325 mg/15mL; HYDROCODONE BITARTRATE 7.5 mg/15mLJul 15, 2026Jul 15, 2026
Redpharm DrugACETAMINOPHEN 325 mg/15mL; HYDROCODONE BITARTRATE 7.5 mg/15mLJul 15, 2026Jul 15, 2026

Roster from daily NDC Directory diffs — first/last seen dates start July 2026.

Cite this page

DrugDashboards, "Hydrocodone Bitartrate and Acetaminophen — NDC 71930-0027-43," retrieved September 3, 2026, https://drugdashboards.com/drug/71930002743.

Free to cite with attribution — see how the data is put together.