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Promethazine Hydrochloride and Codeine Phosphate

Promethazine Hydrochloride and Codeine Phosphate · PROMETHAZINE HYDROCHLORIDE 6.25 mg/5mL; CODEINE PHOSPHATE 10 mg/5mL · Solution · Oral · Bryant Ranch Prepack

NDC 72162-2042-02 · 473 mL in 1 BOTTLE, PLASTIC · ANDA · View full market →

The short version

5 companies supply this market — a reasonable cushion if one runs into trouble. Historically, drugs in this position went on to a new shortage within 90 days about 0.2% of the time — roughly 2× the typical drug (0.1%).

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Medicare Part D

No Medicare Part D plan in CMS's quarterly files lists this product. That usually means it is discontinued, a repackager's listing, or a product no plan has added to its formulary.

How Part D pricing works →

NADAC price per unit

No NADAC pricing on file for this NDC — NADAC covers drugs dispensed by retail community pharmacies.

Supply fragility

Not scored — fragility is computed for NADAC-priced NDCs.

90-day shortage risk (model v2)

0.2%chance of a new FDA shortage posting for promethazine hydrochloride and codeine phosphate (other) in the next 90 days

price up 68% YoY · sole-source market

For scale: the typical drug’s chance is about 0.1% — this one is 2× that.

Backtested statistical model over the whole market, not this package alone. Model details →

Where it's made

Establishments this product's FDA label declares, located via FDA registration data. How we built this →

Regulatory

Application
ANDA200386
TE code
AA
Approval date
Jun 29, 2012
Patents / exclusivity
None on file

Shortage history

No FDA shortage reports for this drug or its presentations.

Recalls (this NDC)

No enforcement reports list this package NDC.

Manufacturers of Promethazine Hydrochloride and Codeine Phosphate (Solution)

LabelerStrengthFirst seenLast seen
Atlantic Biologicals Corp.PROMETHAZINE HYDROCHLORIDE 6.25 mg/5mL; CODEINE PHOSPHATE 10 mg/5mLAug 26, 2026Sep 2, 2026
Bryant Ranch PrepackPROMETHAZINE HYDROCHLORIDE 6.25 mg/5mL; CODEINE PHOSPHATE 10 mg/5mLAug 26, 2026Sep 2, 2026
Cosette Pharmaceuticals, Inc.PROMETHAZINE HYDROCHLORIDE 6.25 mg/5mL; CODEINE PHOSPHATE 10 mg/5mLAug 26, 2026Sep 2, 2026
Cranbury Pharmaceuticals, LLCPROMETHAZINE HYDROCHLORIDE 6.25 mg/5mL; CODEINE PHOSPHATE 10 mg/5mLAug 26, 2026Sep 2, 2026
Quagen Pharmaceuticals LlcPROMETHAZINE HYDROCHLORIDE 6.25 mg/5mL; CODEINE PHOSPHATE 10 mg/5mLAug 26, 2026Sep 2, 2026
Atlantic Biologicals Corp.PROMETHAZINE HYDROCHLORIDE 10 mg/5mL; CODEINE PHOSPHATE 6.25 mg/5mLJul 22, 2026Aug 19, 2026
Bryant Ranch PrepackPROMETHAZINE HYDROCHLORIDE 10 mg/5mL; CODEINE PHOSPHATE 6.25 mg/5mLJul 22, 2026Aug 19, 2026
Cosette Pharmaceuticals, Inc.PROMETHAZINE HYDROCHLORIDE 10 mg/5mL; CODEINE PHOSPHATE 6.25 mg/5mLJul 22, 2026Aug 19, 2026
Cranbury Pharmaceuticals, LLCPROMETHAZINE HYDROCHLORIDE 10 mg/5mL; CODEINE PHOSPHATE 6.25 mg/5mLJul 22, 2026Aug 19, 2026
Quagen Pharmaceuticals LlcPROMETHAZINE HYDROCHLORIDE 10 mg/5mL; CODEINE PHOSPHATE 6.25 mg/5mLJul 22, 2026Aug 19, 2026
Atlantic Biologicals Corp.CODEINE PHOSPHATE 10 mg/5mL; PROMETHAZINE HYDROCHLORIDE 6.25 mg/5mLJul 15, 2026Jul 15, 2026
Bryant Ranch PrepackCODEINE PHOSPHATE 10 mg/5mL; PROMETHAZINE HYDROCHLORIDE 6.25 mg/5mLJul 15, 2026Jul 15, 2026
Cosette Pharmaceuticals, Inc.CODEINE PHOSPHATE 10 mg/5mL; PROMETHAZINE HYDROCHLORIDE 6.25 mg/5mLJul 15, 2026Jul 15, 2026
Cranbury Pharmaceuticals, LLCCODEINE PHOSPHATE 10 mg/5mL; PROMETHAZINE HYDROCHLORIDE 6.25 mg/5mLJul 15, 2026Jul 15, 2026
Quagen Pharmaceuticals LlcCODEINE PHOSPHATE 10 mg/5mL; PROMETHAZINE HYDROCHLORIDE 6.25 mg/5mLJul 15, 2026Jul 15, 2026

Roster from daily NDC Directory diffs — first/last seen dates start July 2026.

Cite this page

DrugDashboards, "Promethazine Hydrochloride and Codeine Phosphate — NDC 72162-2042-02," retrieved September 3, 2026, https://drugdashboards.com/drug/72162204202.

Free to cite with attribution — see how the data is put together.